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IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells.
Novak J, Moldoveanu Z, Renfrow MB, Yanagihara T, Suzuki H, Raska M, Hall S, Brown R, Huang WQ, Goepfert A, Kilian M, Poulsen K, Tomana M, Wyatt RJ, Julian BA, Mestecky J. Novak J, et al. Among authors: brown r. Contrib Nephrol. 2007;157:134-8. doi: 10.1159/000102455. Contrib Nephrol. 2007. PMID: 17495451 Review.
Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins.
Moore JS, Kulhavy R, Tomana M, Moldoveanu Z, Suzuki H, Brown R, Hall S, Kilian M, Poulsen K, Mestecky J, Julian BA, Novak J. Moore JS, et al. Among authors: brown r. Mol Immunol. 2007 Apr;44(10):2598-604. doi: 10.1016/j.molimm.2006.12.011. Epub 2007 Feb 2. Mol Immunol. 2007. PMID: 17275907 Free PMC article.
IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.
Novak J, Raskova Kafkova L, Suzuki H, Tomana M, Matousovic K, Brown R, Hall S, Sanders JT, Eison TM, Moldoveanu Z, Novak L, Novak Z, Mayne R, Julian BA, Mestecky J, Wyatt RJ. Novak J, et al. Among authors: brown r. Nephrol Dial Transplant. 2011 Nov;26(11):3451-7. doi: 10.1093/ndt/gfr448. Epub 2011 Aug 9. Nephrol Dial Transplant. 2011. PMID: 21828345 Free PMC article.
Experimental evidence of pathogenic role of IgG autoantibodies in IgA nephropathy.
Moldoveanu Z, Suzuki H, Reily C, Satake K, Novak L, Xu N, Huang ZQ, Knoppova B, Khan A, Hall S, Yanagawa H, Brown R, Winstead CJ, O'Quinn DB, Weinmann A, Gharavi AG, Kiryluk K, Julian BA, Weaver CT, Suzuki Y, Novak J. Moldoveanu Z, et al. Among authors: brown r. J Autoimmun. 2021 Mar;118:102593. doi: 10.1016/j.jaut.2021.102593. Epub 2021 Jan 25. J Autoimmun. 2021. PMID: 33508637 Free PMC article.
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