Brown SD - Search Results

1

Mutant analysis reveals whirlin as a dynamic organizer in the growing hair cell stereocilium.

Kikkawa Y, Mburu P, Morse S, Kominami R, Townsend S, Brown SD. Kikkawa Y, et al. Among authors: brown sd. Hum Mol Genet. 2005 Feb 1;14(3):391-400. doi: 10.1093/hmg/ddi035. Epub 2004 Dec 8. Hum Mol Genet. 2005. PMID: 15590699

2

Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.

Mburu P, Mustapha M, Varela A, Weil D, El-Amraoui A, Holme RH, Rump A, Hardisty RE, Blanchard S, Coimbra RS, Perfettini I, Parkinson N, Mallon AM, Glenister P, Rogers MJ, Paige AJ, Moir L, Clay J, Rosenthal A, Liu XZ, Blanco G, Steel KP, Petit C, Brown SD. Mburu P, et al. Among authors: brown sd. Nat Genet. 2003 Aug;34(4):421-8. doi: 10.1038/ng1208. Nat Genet. 2003. PMID: 12833159

3

Whirlin complexes with p55 at the stereocilia tip during hair cell development.

Mburu P, Kikkawa Y, Townsend S, Romero R, Yonekawa H, Brown SD. Mburu P, et al. Among authors: brown sd. Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):10973-8. doi: 10.1073/pnas.0600923103. Epub 2006 Jul 7. Proc Natl Acad Sci U S A. 2006. PMID: 16829577 Free PMC article.

4

Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia.

Mburu P, Romero MR, Hilton H, Parker A, Townsend S, Kikkawa Y, Brown SD. Mburu P, et al. Among authors: brown sd. PLoS One. 2010 Jul 16;5(7):e11627. doi: 10.1371/journal.pone.0011627. PLoS One. 2010. PMID: 20661277 Free PMC article.

5

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.

Tateossian H, Morse S, Parker A, Mburu P, Warr N, Acevedo-Arozena A, Cheeseman M, Wells S, Brown SD. Tateossian H, et al. Among authors: brown sd. Hum Mol Genet. 2013 Jul 1;22(13):2553-65. doi: 10.1093/hmg/ddt103. Epub 2013 Mar 3. Hum Mol Genet. 2013. PMID: 23459932 Free PMC article.

6

Quiet as a mouse: dissecting the molecular and genetic basis of hearing.

Brown SD, Hardisty-Hughes RE, Mburu P. Brown SD, et al. Nat Rev Genet. 2008 Apr;9(4):277-90. doi: 10.1038/nrg2309. Epub 2008 Feb 19. Nat Rev Genet. 2008. PMID: 18283275 Review.

7

Protein 4.1 expression in the developing hair cells of the mouse inner ear.

Okumura K, Mochizuki E, Yokohama M, Yamakawa H, Shitara H, Mburu P, Yonekawa H, Brown SD, Kikkawa Y. Okumura K, et al. Among authors: brown sd. Brain Res. 2010 Jan 11;1307:53-62. doi: 10.1016/j.brainres.2009.10.039. Epub 2009 Oct 22. Brain Res. 2010. PMID: 19853587

8

The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.

Olt J, Mburu P, Johnson SL, Parker A, Kuhn S, Bowl M, Marcotti W, Brown SD. Olt J, et al. Among authors: brown sd. PLoS One. 2014 Jan 27;9(1):e87331. doi: 10.1371/journal.pone.0087331. eCollection 2014. PLoS One. 2014. PMID: 24475274 Free PMC article.

9

The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti.

Tsai H, Hardisty RE, Rhodes C, Kiernan AE, Roby P, Tymowska-Lalanne Z, Mburu P, Rastan S, Hunter AJ, Brown SD, Steel KP. Tsai H, et al. Among authors: brown sd. Hum Mol Genet. 2001 Mar 1;10(5):507-12. doi: 10.1093/hmg/10.5.507. Hum Mol Genet. 2001. PMID: 11181574

10

Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media.

Parkinson N, Hardisty-Hughes RE, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD. Parkinson N, et al. Among authors: brown sd. PLoS Genet. 2006 Oct 6;2(10):e149. doi: 10.1371/journal.pgen.0020149. PLoS Genet. 2006. PMID: 17029558 Free PMC article.

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