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CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells.
Kozlova V, Ledererova A, Ladungova A, Peschelova H, Janovska P, Slusarczyk A, Domagala J, Kopcil P, Vakulova V, Oppelt J, Bryja V, Doubek M, Mayer J, Pospisilova S, Smida M. Kozlova V, et al. Among authors: bryja v. PLoS One. 2020 Mar 25;15(3):e0229170. doi: 10.1371/journal.pone.0229170. eCollection 2020. PLoS One. 2020. PMID: 32210425 Free PMC article.
Post-translational modifications regulate signalling by Ror1.
Kaucká M, Krejčí P, Plevová K, Pavlová S, Procházková J, Janovská P, Valnohová J, Kozubík A, Pospíšilová S, Bryja V. Kaucká M, et al. Among authors: bryja v. Acta Physiol (Oxf). 2011 Nov;203(3):351-62. doi: 10.1111/j.1748-1716.2011.02306.x. Epub 2011 May 27. Acta Physiol (Oxf). 2011. PMID: 21481194
The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration.
Kaucká M, Plevová K, Pavlová S, Janovská P, Mishra A, Verner J, Procházková J, Krejcí P, Kotasková J, Ovesná P, Tichy B, Brychtová Y, Doubek M, Kozubík A, Mayer J, Pospísilová S, Bryja V. Kaucká M, et al. Among authors: bryja v. Cancer Res. 2013 Mar 1;73(5):1491-501. doi: 10.1158/0008-5472.CAN-12-1752. Epub 2013 Jan 21. Cancer Res. 2013. PMID: 23338609
Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.
Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V. Janovska P, et al. Among authors: bryja v. Clin Cancer Res. 2016 Jan 15;22(2):459-69. doi: 10.1158/1078-0432.CCR-15-0154. Epub 2015 Aug 3. Clin Cancer Res. 2016. PMID: 26240275 Free PMC article.
ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells.
Kotašková J, Pavlová Š, Greif I, Stehlíková O, Plevová K, Janovská P, Brychtová Y, Doubek M, Pospíšilová Š, Bryja V. Kotašková J, et al. Among authors: bryja v. Br J Haematol. 2016 Oct;175(2):339-342. doi: 10.1111/bjh.13848. Epub 2015 Nov 16. Br J Haematol. 2016. PMID: 26567475 Free article. No abstract available.
COBLL1, LPL and ZAP70 expression defines prognostic subgroups of chronic lymphocytic leukemia patients with high accuracy and correlates with IGHV mutational status.
Plesingerova H, Librova Z, Plevova K, Libra A, Tichy B, Skuhrova Francova H, Vrbacky F, Smolej L, Mayer J, Bryja V, Doubek M, Pospisilova S. Plesingerova H, et al. Among authors: bryja v. Leuk Lymphoma. 2017 Jan;58(1):70-79. doi: 10.1080/10428194.2016.1180690. Epub 2016 May 17. Leuk Lymphoma. 2017. PMID: 27185377
WNT5A: a motility-promoting factor in Hodgkin lymphoma.
Linke F, Zaunig S, Nietert MM, von Bonin F, Lutz S, Dullin C, Janovská P, Beissbarth T, Alves F, Klapper W, Bryja V, Pukrop T, Trümper L, Wilting J, Kube D. Linke F, et al. Among authors: bryja v. Oncogene. 2017 Jan 5;36(1):13-23. doi: 10.1038/onc.2016.183. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270428
Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma.
Linke F, Harenberg M, Nietert MM, Zaunig S, von Bonin F, Arlt A, Szczepanowski M, Weich HA, Lutz S, Dullin C, Janovská P, Krafčíková M, Trantírek L, Ovesná P, Klapper W, Beissbarth T, Alves F, Bryja V, Trümper L, Wilting J, Kube D. Linke F, et al. Among authors: bryja v. Leukemia. 2017 Feb;31(2):361-372. doi: 10.1038/leu.2016.232. Epub 2016 Aug 18. Leukemia. 2017. PMID: 27535218
Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.
Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, Paruch K, Trbusek M. Zemanova J, et al. Among authors: bryja v. Oncotarget. 2016 Sep 20;7(38):62091-62106. doi: 10.18632/oncotarget.11388. Oncotarget. 2016. PMID: 27556692 Free PMC article.
140 results