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Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Bojarski AJ, et al. Among authors: bugno r. Bioorg Med Chem. 2006 Mar 1;14(5):1391-402. doi: 10.1016/j.bmc.2005.09.060. Epub 2005 Nov 2. Bioorg Med Chem. 2006. PMID: 16266808
The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E. Paluchowska MH, et al. Among authors: bugno r. Bioorg Med Chem. 2007 Nov 15;15(22):7116-25. doi: 10.1016/j.bmc.2007.07.029. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17825569
38 results