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Page 1
Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.
J Med Chem. 2012 Jun 14;55(11):5467-82. doi: 10.1021/jm300403a. Epub 2012 May 17.
J Med Chem. 2012.
PMID: 22548342
Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.
Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, DeFina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, Joshi A, Kennedy AR, Kim AI, Lara K, Lee J, Li J, Lougheed JC, Ma S, Malek S, Manalo JC, Martini JF, McGrath G, Nicoll M, Nuss JM, Pack M, Peto CJ, Tsang TH, Wang L, Womble SW, Yakes M, Zhang W, Rice KD.
Bussenius J, et al. Among authors: buhr ca.
Bioorg Med Chem Lett. 2012 Sep 1;22(17):5396-404. doi: 10.1016/j.bmcl.2012.07.052. Epub 2012 Jul 21.
Bioorg Med Chem Lett. 2012.
PMID: 22877636
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Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).
Takeuchi CS, Kim BG, Blazey CM, Ma S, Johnson HW, Anand NK, Arcalas A, Baik TG, Buhr CA, Cannoy J, Epshteyn S, Joshi A, Lara K, Lee MS, Wang L, Leahy JW, Nuss JM, Aay N, Aoyama R, Foster P, Lee J, Lehoux I, Munagala N, Plonowski A, Rajan S, Woolfrey J, Yamaguchi K, Lamb P, Miller N.
Takeuchi CS, et al. Among authors: buhr ca.
J Med Chem. 2013 Mar 28;56(6):2218-34. doi: 10.1021/jm3007933. Epub 2013 Mar 7.
J Med Chem. 2013.
PMID: 23394126
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Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway.
Yu P, Laird AD, Du X, Wu J, Won KA, Yamaguchi K, Hsu PP, Qian F, Jaeger CT, Zhang W, Buhr CA, Shen P, Abulafia W, Chen J, Young J, Plonowski A, Yakes FM, Chu F, Lee M, Bentzien F, Lam ST, Dale S, Matthews DJ, Lamb P, Foster P.
Yu P, et al. Among authors: buhr ca.
Mol Cancer Ther. 2014 May;13(5):1078-91. doi: 10.1158/1535-7163.MCT-13-0709. Epub 2014 Mar 14.
Mol Cancer Ther. 2014.
PMID: 24634413
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Differential downregulation of e-cadherin and desmoglein by epidermal growth factor.
Chavez MG, Buhr CA, Petrie WK, Wandinger-Ness A, Kusewitt DF, Hudson LG.
Chavez MG, et al. Among authors: buhr ca.
Dermatol Res Pract. 2012;2012:309587. doi: 10.1155/2012/309587. Epub 2012 Jan 16.
Dermatol Res Pract. 2012.
PMID: 22312325
Free PMC article.
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Mesenchymal transformation in epithelial ovarian tumor cells expressing epidermal growth factor receptor variant III.
Zeineldin R, Rosenberg M, Ortega D, Buhr C, Chavez MG, Stack MS, Kusewitt DF, Hudson LG.
Zeineldin R, et al.
Mol Carcinog. 2006 Nov;45(11):851-60. doi: 10.1002/mc.20237.
Mol Carcinog. 2006.
PMID: 16788982
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Oligodeoxynucleotides containing C-7 propyne analogs of 7-deaza-2'-deoxyguanosine and 7-deaza-2'-deoxyadenosine.
Buhr CA, Wagner RW, Grant D, Froehler BC.
Buhr CA, et al.
Nucleic Acids Res. 1996 Aug 1;24(15):2974-80. doi: 10.1093/nar/24.15.2974.
Nucleic Acids Res. 1996.
PMID: 8760882
Free PMC article.
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Stability study of nitroglycerin sublingual tablets.
Page DP, Carson NA, Buhr CA, Flinn PE, Wells CE, Randall MT.
Page DP, et al. Among authors: buhr ca.
J Pharm Sci. 1975 Jan;64(1):140-7. doi: 10.1002/jps.2600640133.
J Pharm Sci. 1975.
PMID: 805832
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