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G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness.
Dbouk HA, Vadas O, Shymanets A, Burke JE, Salamon RS, Khalil BD, Barrett MO, Waldo GL, Surve C, Hsueh C, Perisic O, Harteneck C, Shepherd PR, Harden TK, Smrcka AV, Taussig R, Bresnick AR, Nürnberg B, Williams RL, Backer JM. Dbouk HA, et al. Among authors: burke je. Sci Signal. 2012 Dec 4;5(253):ra89. doi: 10.1126/scisignal.2003264. Sci Signal. 2012. PMID: 23211529 Free PMC article.
Recognition of protein-linked glycans as a determinant of peptidase activity.
Noach I, Ficko-Blean E, Pluvinage B, Stuart C, Jenkins ML, Brochu D, Buenbrazo N, Wakarchuk W, Burke JE, Gilbert M, Boraston AB. Noach I, et al. Among authors: burke je. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E679-E688. doi: 10.1073/pnas.1615141114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096352 Free PMC article.
Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans.
Takeda AJ, Zhang Y, Dornan GL, Siempelkamp BD, Jenkins ML, Matthews HF, McElwee JJ, Bi W, Seeborg FO, Su HC, Burke JE, Lucas CL. Takeda AJ, et al. Among authors: burke je. J Allergy Clin Immunol. 2017 Oct;140(4):1152-1156.e10. doi: 10.1016/j.jaci.2017.03.026. Epub 2017 Apr 13. J Allergy Clin Immunol. 2017. PMID: 28414062 Free PMC article. No abstract available.
158 results