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Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons.
Steg LC, Shireby GL, Imm J, Davies JP, Franklin A, Flynn R, Namboori SC, Bhinge A, Jeffries AR, Burrage J, Neilson GWA, Walker EM, Perfect LW, Price J, McAlonan G, Srivastava DP, Bray NJ, Cope EL, Jones KM, Allen ND, Pishva E, Dempster EL, Lunnon K, Mill J, Hannon E. Steg LC, et al. Among authors: burrage j. Mol Brain. 2021 Jun 26;14(1):98. doi: 10.1186/s13041-021-00810-w. Mol Brain. 2021. PMID: 34174924 Free PMC article.
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types.
Shireby G, Dempster EL, Policicchio S, Smith RG, Pishva E, Chioza B, Davies JP, Burrage J, Lunnon K, Seiler Vellame D, Love S, Thomas A, Brookes K, Morgan K, Francis P, Hannon E, Mill J. Shireby G, et al. Among authors: burrage j. Nat Commun. 2022 Sep 24;13(1):5620. doi: 10.1038/s41467-022-33394-7. Nat Commun. 2022. PMID: 36153390 Free PMC article.
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J. Lunnon K, et al. Among authors: burrage j. Nat Neurosci. 2014 Sep;17(9):1164-70. doi: 10.1038/nn.3782. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129077 Free PMC article.
Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.
Lunnon K, Hannon E, Smith RG, Dempster E, Wong C, Burrage J, Troakes C, Al-Sarraj S, Kepa A, Schalkwyk L, Mill J. Lunnon K, et al. Among authors: burrage j. Genome Biol. 2016 Feb 16;17:27. doi: 10.1186/s13059-016-0871-x. Genome Biol. 2016. PMID: 26883014 Free PMC article.
THE AUTHORS REPLY.
Hughes A, Bao Y, Smart M, Gorrie-Stone T, Hannon E, Mill J, Burrage J, Schalkwyk L, Kumari M. Hughes A, et al. Among authors: burrage j. Am J Epidemiol. 2019 Feb 1;188(2):488-489. doi: 10.1093/aje/kwy247. Am J Epidemiol. 2019. PMID: 30380002 No abstract available.
78 results