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SAR of Novel 3-Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules.
Elhemely MA, Belgath AA, El-Sayed S, Burusco KK, Kadirvel M, Tirella A, Finegan K, Bryce RA, Stratford IJ, Freeman S. Elhemely MA, et al. Among authors: burusco kk. J Med Chem. 2022 Mar 24;65(6):4783-4797. doi: 10.1021/acs.jmedchem.1c01936. Epub 2022 Mar 15. J Med Chem. 2022. PMID: 35290041 Free PMC article.
Lead Optimization of Dehydroemetine for Repositioned Use in Malaria.
Panwar P, Burusco KK, Abubaker M, Matthews H, Gutnov A, Fernández-Álvaro E, Bryce RA, Wilkinson J, Nirmalan N. Panwar P, et al. Among authors: burusco kk. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e01444-19. doi: 10.1128/AAC.01444-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31964796 Free PMC article.
14 results