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Four-week inhibition of the renin-angiotensin system in spontaneously hypertensive rats results in persistently lower blood pressure with reduced kidney renin and changes in expression of relevant gene networks.
Byars SG, Prestes P, Suphapimol V, Takeuchi F, De Vries N, Maier MC, Melo M, Balding D, Samani N, Allen AM, Kato N, Wilkinson-Berka JL, Charchar F, Harrap SB. Byars SG, et al. Cardiovasc Res. 2024 Mar 19:cvae053. doi: 10.1093/cvr/cvae053. Online ahead of print. Cardiovasc Res. 2024. PMID: 38501595
Antagonistic Pleiotropy in Human Disease.
Byars SG, Voskarides K. Byars SG, et al. J Mol Evol. 2020 Jan;88(1):12-25. doi: 10.1007/s00239-019-09923-2. Epub 2019 Dec 21. J Mol Evol. 2020. PMID: 31863128 Review.
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