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2011 1
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Page 1
Association study between C10orf90 gene polymorphisms and colorectal cancer.
Song J, Wang K, Chen Z, Zhong D, Li L, Guo L, Yu S. Song J, et al. Front Oncol. 2023 Jul 31;13:1192378. doi: 10.3389/fonc.2023.1192378. eCollection 2023. Front Oncol. 2023. PMID: 37588090 Free PMC article.
The morbidity and mortality rates in Western countries have decreased, but they are still on the rise in China. C10orf90 is associated with a variety of cancers, but the correlation between C10orf90 and CRC is not yet known. ...Moreover, rs12412320 had the mo …
The morbidity and mortality rates in Western countries have decreased, but they are still on the rise in China. C10orf90 is associate …
The plasma peptides of Alzheimer's disease.
Florentinus-Mefailoski A, Bowden P, Scheltens P, Killestein J, Teunissen C, Marshall JG. Florentinus-Mefailoski A, et al. Clin Proteomics. 2021 Jun 28;18(1):17. doi: 10.1186/s12014-021-09320-2. Clin Proteomics. 2021. PMID: 34182925 Free PMC article.
The endogenous tryptic peptides of Alzheimer's were compared to normals, multiple sclerosis, ovarian cancer, breast cancer, female normal, sepsis, ICU Control, heart attack, along with their institution-matched controls, and normal samples collected directly onto ic …
The endogenous tryptic peptides of Alzheimer's were compared to normals, multiple sclerosis, ovarian cancer, breast cancer, fe …
A functional genetic variant in fragile-site gene FATS modulates the risk of breast cancer in triparous women.
Song F, Zhang J, Qiu L, Zhao Y, Xing P, Lu J, Chen K, Li Z. Song F, et al. BMC Cancer. 2015 Jul 30;15:559. doi: 10.1186/s12885-015-1570-9. BMC Cancer. 2015. PMID: 26223354 Free PMC article.
BACKGROUND: The fragile-site associated tumor suppressor (FATS, formerly known as C10orf90), a regulator of p53-p21 pathway has been involved in the onset of breast cancer. ...Case-control studies found that CT or TT genotype was significantly associated with a prot …
BACKGROUND: The fragile-site associated tumor suppressor (FATS, formerly known as C10orf90), a regulator of p53-p21 pathway has been …
Transcriptome Analysis of Pterygium and Pinguecula Reveals Evidence of Genomic Instability Associated with Chronic Inflammation.
Suarez MF, Echenique J, López JM, Medina E, Irós M, Serra HM, Fini ME. Suarez MF, et al. Int J Mol Sci. 2021 Nov 8;22(21):12090. doi: 10.3390/ijms222112090. Int J Mol Sci. 2021. PMID: 34769520 Free PMC article.
Among the top DEGs were four genes encoding tumor suppressors that were downregulated in pterygium: C10orf90, RARRES1, DMBT1 and SCGB3A1; C10orf90 and RARRES1 were also downregulated in pinguecula. Ingenuity Pathway Analysis overwhelmingly linked DEGs to cancer …
Among the top DEGs were four genes encoding tumor suppressors that were downregulated in pterygium: C10orf90, RARRES1, DMBT1 and SCGB …
Conjunctival melanoma copy number alterations and correlation with mutation status, tumor features, and clinical outcome.
Kenawy N, Kalirai H, Sacco JJ, Lake SL, Heegaard S, Larsen AC, Finger PT, Milman T, Chin K, Mosci C, Lanza F, Moulin A, Schmitt CA, Caujolle JP, Maschi C, Marinkovic M, Taktak AF, Heimann H, Damato BE, Coupland SE. Kenawy N, et al. Pigment Cell Melanoma Res. 2019 Jul;32(4):564-575. doi: 10.1111/pcmr.12767. Epub 2019 Feb 19. Pigment Cell Melanoma Res. 2019. PMID: 30672666 Free PMC article.
Deletions on chr 10q11.21-26.2, a region harboring the tumor suppressor genes, PDCD4, SUFU, NEURL1, PTEN, RASSF4, DMBT1, and C10orf90 and C10orf99, significantly correlated with metastasis (Fisher's exact, p 0.04), lymphatic invasion (Fisher's exact, p 0.02), increasing tu …
Deletions on chr 10q11.21-26.2, a region harboring the tumor suppressor genes, PDCD4, SUFU, NEURL1, PTEN, RASSF4, DMBT1, and C10orf90 …
Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide.
Hunter FW, Devaux JBL, Meng F, Hong CR, Khan A, Tsai P, Ketela TW, Sharma I, Kakadia PM, Marastoni S, Shalev Z, Hickey AJR, Print CG, Bohlander SK, Hart CP, Wouters BG, Wilson WR. Hunter FW, et al. Mol Pharmacol. 2019 Jun;95(6):638-651. doi: 10.1124/mol.118.115196. Epub 2019 Apr 12. Mol Pharmacol. 2019. PMID: 30979813
Evofosfamide (TH-302) is a hypoxia-activated DNA-crosslinking prodrug currently in clinical development for cancer therapy. Oxygen-sensitive activation of evofosfamide depends on one-electron reduction, yet the reductases that catalyze this process in tumors are unknown. . …
Evofosfamide (TH-302) is a hypoxia-activated DNA-crosslinking prodrug currently in clinical development for cancer therapy. Oxygen-se …
The value of FATS expression in predicting sensitivity to radiotherapy in breast cancer.
Zhang J, Wu N, Zhang T, Sun T, Su Y, Zhao J, Mu K, Jin Z, Gao M, Liu J, Gu L. Zhang J, et al. Oncotarget. 2017 Jun 13;8(24):38491-38500. doi: 10.18632/oncotarget.16630. Oncotarget. 2017. PMID: 28402275 Free PMC article.
FATS function was examined in breast cancer cell lines using siRNA knock-downs and colony forming assays after irradiation. CONCLUSIONS: FATS status is a biomarker in breast cancer to identify individuals likely to benefit from radiotherapy....
FATS function was examined in breast cancer cell lines using siRNA knock-downs and colony forming assays after irradiation. CONCLUSIO …
FATS expression is associated with cisplatin sensitivity in non small cell lung cancer.
Tian Y, Zhang J, Yan S, Qiu L, Li Z. Tian Y, et al. Lung Cancer. 2012 Jun;76(3):416-22. doi: 10.1016/j.lungcan.2011.11.009. Epub 2011 Dec 2. Lung Cancer. 2012. PMID: 22137560
BACKGROUND: Although the survival benefit of cisplatin-based adjuvant chemotherapy has been proven for patients with non small cell lung cancer (NSCLC), the resistance to cisplatin and its dose-dependent side effects remain a challenge. ...
BACKGROUND: Although the survival benefit of cisplatin-based adjuvant chemotherapy has been proven for patients with non small cell lung …
[Expression of FATS in non-small cell lung cancer and its relationship with prognosis].
Zhang TM, Zhang J, Zhou DJ, Wang CL. Zhang TM, et al. Zhonghua Zhong Liu Za Zhi. 2019 Nov 23;41(11):826-830. doi: 10.3760/cma.j.issn.0253-3766.2019.11.005. Zhonghua Zhong Liu Za Zhi. 2019. PMID: 31770849 Chinese.
Objective: To investigate the expression of fragile-site associated tumor suppressor (FATS) in non-small cell lung cancer and its relationship with clinicopathological features and prognosis. Methods: A total of 140 non-small cell lung cancer (NSCLC) cases and 30 ad …
Objective: To investigate the expression of fragile-site associated tumor suppressor (FATS) in non-small cell lung cancer and its rel …
11 results