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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2009 | 3 |
2010 | 5 |
2024 | 0 |
Search Results
7 results
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Page 1
Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor.
J Med Chem. 2010 Dec 23;53(24):8663-78. doi: 10.1021/jm101177s. Epub 2010 Nov 16.
J Med Chem. 2010.
PMID: 21080647
Probing the probes: fitness factors for small molecule tools.
Workman P, Collins I.
Workman P, et al.
Chem Biol. 2010 Jun 25;17(6):561-77. doi: 10.1016/j.chembiol.2010.05.013.
Chem Biol. 2010.
PMID: 20609406
Free PMC article.
Review.
Item in Clipboard
Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases.
Matthews TP, McHardy T, Klair S, Boxall K, Fisher M, Cherry M, Allen CE, Addison GJ, Ellard J, Aherne GW, Westwood IM, van Montfort R, Garrett MD, Reader JC, Collins I.
Matthews TP, et al.
Bioorg Med Chem Lett. 2010 Jul 15;20(14):4045-9. doi: 10.1016/j.bmcl.2010.05.096. Epub 2010 May 27.
Bioorg Med Chem Lett. 2010.
PMID: 20561787
Item in Clipboard
Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt).
McHardy T, Caldwell JJ, Cheung KM, Hunter LJ, Taylor K, Rowlands M, Ruddle R, Henley A, de Haven Brandon A, Valenti M, Davies TG, Fazal L, Seavers L, Raynaud FI, Eccles SA, Aherne GW, Garrett MD, Collins I.
McHardy T, et al.
J Med Chem. 2010 Mar 11;53(5):2239-49. doi: 10.1021/jm901788j.
J Med Chem. 2010.
PMID: 20151677
Free PMC article.
Item in Clipboard
Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2.
Hilton S, Naud S, Caldwell JJ, Boxall K, Burns S, Anderson VE, Antoni L, Allen CE, Pearl LH, Oliver AW, Wynne Aherne G, Garrett MD, Collins I.
Hilton S, et al.
Bioorg Med Chem. 2010 Jan 15;18(2):707-18. doi: 10.1016/j.bmc.2009.11.058. Epub 2009 Dec 6.
Bioorg Med Chem. 2010.
PMID: 20022510
Item in Clipboard
Fragment-based discovery of inhibitors of protein kinase B.
Davies TG, Woodhead SJ, Collins I.
Davies TG, et al.
Curr Top Med Chem. 2009;9(18):1705-17. doi: 10.2174/156802609790102419.
Curr Top Med Chem. 2009.
PMID: 19929839
Review.
Item in Clipboard
Identification of inhibitors of checkpoint kinase 1 through template screening.
Matthews TP, Klair S, Burns S, Boxall K, Cherry M, Fisher M, Westwood IM, Walton MI, McHardy T, Cheung KM, Van Montfort R, Williams D, Aherne GW, Garrett MD, Reader J, Collins I.
Matthews TP, et al.
J Med Chem. 2009 Aug 13;52(15):4810-9. doi: 10.1021/jm900314j.
J Med Chem. 2009.
PMID: 19572549
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