CA49837/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2001	2
2002	1
2006	2
2007	2
2008	1
2011	4
2024	0

1

Vitamin A in reproduction and development.

Clagett-Dame M, Knutson D. Clagett-Dame M, et al. Nutrients. 2011 Apr;3(4):385-428. doi: 10.3390/nu3040385. Epub 2011 Mar 29. Nutrients. 2011. PMID: 22254103 Free PMC article. Review.

2

4-Hydroxybenzyl modification of the highly teratogenic retinoid, 4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)-1-propen-1-yl]benzoic acid (TTNPB), yields a compound that induces apoptosis in breast cancer cells and shows reduced teratogenicity.

Anding AL, Nieves NJ, Abzianidze VV, Collins MD, Curley RW Jr, Clagett-Dame M. Anding AL, et al. Chem Res Toxicol. 2011 Nov 21;24(11):1853-61. doi: 10.1021/tx200174n. Epub 2011 Oct 19. Chem Res Toxicol. 2011. PMID: 21939267

3

An improved synthesis of the C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.

Walker JR, Alshafie G, Abou-Issa H, Curley RW Jr. Walker JR, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2447-50. doi: 10.1016/s0960-894x(02)00427-4. Bioorg Med Chem Lett. 2002. PMID: 12161154

4

Identification of dihydroceramide desaturase as a direct in vitro target for fenretinide.

Rahmaniyan M, Curley RW Jr, Obeid LM, Hannun YA, Kraveka JM. Rahmaniyan M, et al. J Biol Chem. 2011 Jul 15;286(28):24754-64. doi: 10.1074/jbc.M111.250779. Epub 2011 May 4. J Biol Chem. 2011. PMID: 21543327 Free PMC article.

5

Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure.

Cooper JP, Hwang K, Singh H, Wang D, Reynolds CP, Curley RW Jr, Williams SC, Maurer BJ, Kang MH. Cooper JP, et al. Br J Pharmacol. 2011 Jul;163(6):1263-75. doi: 10.1111/j.1476-5381.2011.01310.x. Br J Pharmacol. 2011. PMID: 21391977 Free PMC article.

6

The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor.

Anding AL, Chapman JS, Barnett DW, Curley RW Jr, Clagett-Dame M. Anding AL, et al. Cancer Res. 2007 Jul 1;67(13):6270-7. doi: 10.1158/0008-5472.CAN-07-0727. Cancer Res. 2007. PMID: 17616685

7

An unhydrolyzable analogue of N-(4-hydroxyphenyl)retinamide. synthesis and preliminary biological studies.

Weiss KL, Alshafie G, Chapman JS, Mershon SM, Abou-Issa H, Clagett-Dame M, Curley RW Jr. Weiss KL, et al. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1583-6. doi: 10.1016/s0960-894x(01)00230-x. Bioorg Med Chem Lett. 2001. PMID: 11412986

8

Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide.

Walker JR, Alshafie G, Nieves N, Ahrens J, Clagett-Dame M, Abou-Issa H, Curley RW Jr. Walker JR, et al. Bioorg Med Chem. 2006 May 1;14(9):3038-48. doi: 10.1016/j.bmc.2005.12.044. Epub 2006 Jan 10. Bioorg Med Chem. 2006. PMID: 16412653 Free PMC article.

9

Virtual coupling of pyran protons in the 1H NMR spectra of C- and N-glucuronides [correction]: dependence on substitution and solvent.

Panigot MJ, Robarge MJ, Curley RW Jr. Panigot MJ, et al. AAPS PharmSci. 2001;3(1):E4. doi: 10.1208/ps030104. AAPS PharmSci. 2001. PMID: 11741255 Free PMC article.

10

4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines.

Villani MG, Appierto V, Cavadini E, Bettiga A, Prinetti A, Clagett-Dame M, Curley RW, Formelli F. Villani MG, et al. Cancer Res. 2006 Mar 15;66(6):3238-47. doi: 10.1158/0008-5472.CAN-05-3362. Cancer Res. 2006. PMID: 16540676

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