CA80175/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	3
2001	2
2002	4
2003	1
2004	2
2005	1
2006	1
2009	1
2024	0

1

Panhandle PCR approaches to cloning MLL genomic breakpoint junctions and fusion transcript sequences.

Robinson BW, Felix CA. Robinson BW, et al. Methods Mol Biol. 2009;538:85-114. doi: 10.1007/978-1-59745-418-6_6. Methods Mol Biol. 2009. PMID: 19277575

2

BglII-based panhandle and reverse panhandle PCR approaches increase capability for cloning der(II) and der(other) genomic breakpoint junctions of MLL translocations.

Robinson BW, Slater DJ, Felix CA. Robinson BW, et al. Genes Chromosomes Cancer. 2006 Aug;45(8):740-53. doi: 10.1002/gcc.20336. Genes Chromosomes Cancer. 2006. PMID: 16703585

3

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

Mistry AR, Felix CA, Whitmarsh RJ, Mason A, Reiter A, Cassinat B, Parry A, Walz C, Wiemels JL, Segal MR, Adès L, Blair IA, Osheroff N, Peniket AJ, Lafage-Pochitaloff M, Cross NC, Chomienne C, Solomon E, Fenaux P, Grimwade D. Mistry AR, et al. N Engl J Med. 2005 Apr 14;352(15):1529-38. doi: 10.1056/NEJMoa042715. N Engl J Med. 2005. PMID: 15829534 Free article.

4

The molecular basis of leukemia.

Gilliland DG, Jordan CT, Felix CA. Gilliland DG, et al. Hematology Am Soc Hematol Educ Program. 2004:80-97. doi: 10.1182/asheducation-2004.1.80. Hematology Am Soc Hematol Educ Program. 2004. PMID: 15561678 Review.

5

1,4-Benzoquinone is a topoisomerase II poison.

Lindsey RH Jr, Bromberg KD, Felix CA, Osheroff N. Lindsey RH Jr, et al. Biochemistry. 2004 Jun 15;43(23):7563-74. doi: 10.1021/bi049756r. Biochemistry. 2004. PMID: 15182198

6

Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.

Whitmarsh RJ, Saginario C, Zhuo Y, Hilgenfeld E, Rappaport EF, Megonigal MD, Carroll M, Liu M, Osheroff N, Cheung NK, Slater DJ, Ried T, Knutsen T, Blair IA, Felix CA. Whitmarsh RJ, et al. Oncogene. 2003 Nov 20;22(52):8448-59. doi: 10.1038/sj.onc.1207052. Oncogene. 2003. PMID: 14627986

7

Low NAD(P)H:quinone oxidoreductase activity is associated with increased risk of leukemia with MLL translocations in infants and children.

Smith MT, Wang Y, Skibola CF, Slater DJ, Lo Nigro L, Nowell PC, Lange BJ, Felix CA. Smith MT, et al. Blood. 2002 Dec 15;100(13):4590-3. doi: 10.1182/blood-2001-12-0264. Epub 2002 Aug 1. Blood. 2002. PMID: 12393620 Free article.

8

MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site.

Slater DJ, Hilgenfeld E, Rappaport EF, Shah N, Meek RG, Williams WR, Lovett BD, Osheroff N, Autar RS, Ried T, Felix CA. Slater DJ, et al. Oncogene. 2002 Jul 11;21(30):4706-14. doi: 10.1038/sj.onc.1205572. Oncogene. 2002. PMID: 12096348

9

p53 mutations in leukemia and myelodysplastic syndrome after ovarian cancer.

Leonard DG, Travis LB, Addya K, Dores GM, Holowaty EJ, Bergfeldt K, Malkin D, Kohler BA, Lynch CF, Wiklund T, Stovall M, Hall P, Pukkala E, Slater DJ, Felix CA. Leonard DG, et al. Clin Cancer Res. 2002 May;8(5):973-85. Clin Cancer Res. 2002. PMID: 12006509

10

Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.

Raffini LJ, Slater DJ, Rappaport EF, Lo Nigro L, Cheung NK, Biegel JA, Nowell PC, Lange BJ, Felix CA. Raffini LJ, et al. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4568-73. doi: 10.1073/pnas.062066799. Proc Natl Acad Sci U S A. 2002. PMID: 11930009 Free PMC article.

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