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Did you mean calcrl cancer (55 results)?
CALCR knockdown inhibits the development and progression of non-small-cell lung cancer.
He T, Ling F. He T, et al. Carcinogenesis. 2021 Nov 12;42(11):1390-1398. doi: 10.1093/carcin/bgab076. Carcinogenesis. 2021. PMID: 34417812
G-protein-coupled receptors (GPCRs) have been reported to participate in the occurrence and development of a variety of human cancers. CALCR is one of the hundreds of GPCRs, but its expression level and functional importance have never been investigated in non-small …
G-protein-coupled receptors (GPCRs) have been reported to participate in the occurrence and development of a variety of human cancers …
Loss-of-Function Mutations in Calcitonin Receptor (CALCR) Identify Highly Aggressive Glioblastoma with Poor Outcome.
Pal J, Patil V, Kumar A, Kaur K, Sarkar C, Somasundaram K. Pal J, et al. Clin Cancer Res. 2018 Mar 15;24(6):1448-1458. doi: 10.1158/1078-0432.CCR-17-1901. Epub 2017 Dec 20. Clin Cancer Res. 2018. PMID: 29263181
WT CALCR, but not the mutant versions, inhibited Ras-mediated transformation of immortalized astrocytes in vitro Furthermore, calcitonin inhibited patient-derived neurosphere growth and in vivo glioma tumor growth in a mouse model.Conclusions: We demonstrate CT-CALCR …
WT CALCR, but not the mutant versions, inhibited Ras-mediated transformation of immortalized astrocytes in vitro Furthermore, calcito …
Immune Infiltration in Gastric Cancer Microenvironment and Its Clinical Significance.
Zhang AZ, Yuan X, Liang WH, Zhang HJ, Li Y, Xie YF, Li JF, Jiang CH, Li FP, Shen XH, Pang LJ, Zou H, Zhou WH, Li F, Hu JM. Zhang AZ, et al. Front Cell Dev Biol. 2022 Feb 17;9:762029. doi: 10.3389/fcell.2021.762029. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35252217 Free PMC article.
Immunotherapy has developed rapidly and has gradually become one of the important methods for treatment of gastric cancer (GC). The research on tumor infiltrating immune cells (TIICs) and immune-related genes in the tumor microenvironment (TME) greatly encourages the devel …
Immunotherapy has developed rapidly and has gradually become one of the important methods for treatment of gastric cancer (GC). The r …
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing.
Dowsett GKC, Lam BYH, Tadross JA, Cimino I, Rimmington D, Coll AP, Polex-Wolf J, Knudsen LB, Pyke C, Yeo GSH. Dowsett GKC, et al. Mol Metab. 2021 Nov;53:101240. doi: 10.1016/j.molmet.2021.101240. Epub 2021 May 4. Mol Metab. 2021. PMID: 33962048 Free PMC article.
Interestingly, we identified that the oligodendrocyte population was particularly transcriptionally sensitive to an overnight fast. The receptors GLP1R, GIPR, GFRAL, and CALCR, which bind GLP1, GIP, GDF15, and amylin, respectively, are all expressed in the hindbrain and ar …
Interestingly, we identified that the oligodendrocyte population was particularly transcriptionally sensitive to an overnight fast. The rece …
Genome-Wide Investigation of Genes Regulated by ERalpha in Breast Cancer Cells.
Wang S, Li X, Zhang W, Gao Y, Zhang K, Hao Q, Li W, Wang Z, Li M, Zhang W, Zhang Y, Zhang C. Wang S, et al. Molecules. 2018 Oct 5;23(10):2543. doi: 10.3390/molecules23102543. Molecules. 2018. PMID: 30301189 Free PMC article.
Estrogen receptor alpha (ERalpha), which has been detected in over 70% of breast cancer cases, is a driving factor for breast cancer growth. For investigating the underlying genes and networks regulated by ERalpha in breast cancer, RNA-seq was performed betwe …
Estrogen receptor alpha (ERalpha), which has been detected in over 70% of breast cancer cases, is a driving factor for breast canc …
Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma.
Gupta P, Furness SGB, Bittencourt L, Hare DL, Wookey PJ. Gupta P, et al. Ther Adv Med Oncol. 2020 Dec 18;12:1758835920978110. doi: 10.1177/1758835920978110. eCollection 2020. Ther Adv Med Oncol. 2020. PMID: 33425026 Free PMC article. Review.
Both CT responders and non-responders were sensitive to an immunotoxin based on an anti-CT Receptor antibody. The CALCR mRNA exhibits alternative splicing commonly associated with cancer cells, which could result in the atypical pharmacology exhibited by CT non-resp …
Both CT responders and non-responders were sensitive to an immunotoxin based on an anti-CT Receptor antibody. The CALCR mRNA exhibits …
Imprinted survival genes preclude loss of heterozygosity of chromosome 7 in cancer cells.
Boot A, Oosting J, de Miranda NF, Zhang Y, Corver WE, van de Water B, Morreau H, van Wezel T. Boot A, et al. J Pathol. 2016 Sep;240(1):72-83. doi: 10.1002/path.4756. J Pathol. 2016. PMID: 27265324
The genomes of a wide range of cancers, including colon, breast, and thyroid cancers, frequently show copy number gains of chromosome 7 and rarely show loss of heterozygosity. ...Subsequent knockdown of gene expression showed that CALCR, COPG2, GRB10, KLF14, …
The genomes of a wide range of cancers, including colon, breast, and thyroid cancers, frequently show copy number gains of chr …
Highlights on the Effects of Non-Coding RNAs in the Osteonecrosis of the Jaw.
Caserta S, Stagno F, Gangemi S, Allegra A. Caserta S, et al. Int J Mol Sci. 2024 Jan 27;25(3):1598. doi: 10.3390/ijms25031598. Int J Mol Sci. 2024. PMID: 38338876 Free PMC article. Review.
Interestingly, it has been proved that miR-29 and miR-31-5p, acting on specific targets such as CALCR and RhoA, promote programmed-cell death and consequently the necrosis of bone tissue. ...
Interestingly, it has been proved that miR-29 and miR-31-5p, acting on specific targets such as CALCR and RhoA, promote programmed-ce …
Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer.
Sinha KM, Bagheri-Yarmand R, Lahiri S, Lu Y, Zhang M, Amra S, Rizvi Y, Wan X, Navone N, Ozpolat B, Logothetis C, Gagel RF, Huard J. Sinha KM, et al. Oncogene. 2019 Jun;38(25):5038-5049. doi: 10.1038/s41388-019-0774-x. Epub 2019 Mar 11. Oncogene. 2019. PMID: 30858546
Epigenetic changes that cause dysregulated gene expression during progression of androgen-independent prostate cancer (PCa) and metastatic skeletal lesions remain elusive. Here, we explored the role of histone demethylase NO66 in the pathogenesis of PCa and bone metastasis …
Epigenetic changes that cause dysregulated gene expression during progression of androgen-independent prostate cancer (PCa) and metas …
Identification of hub genes correlated with the pathogenesis and prognosis of gastric cancer via bioinformatics methods.
Nie K, Shi L, Wen Y, Pan J, Li P, Zheng Z, Liu F. Nie K, et al. Minerva Med. 2020 Jun;111(3):213-225. doi: 10.23736/S0026-4806.19.06166-4. Epub 2019 Oct 14. Minerva Med. 2020. PMID: 31638362
BACKGROUND: Gastric cancer (GC) is the fourth most common cause of cancer-related deaths in the world and 5-year overall survival (OS) rate is less than 10%. ...Lastly, we build a seven-gene prognosis signature (CYP19A1, SERPINE1, CGB5, CALCR, ASGR2, CYTL1 an …
BACKGROUND: Gastric cancer (GC) is the fourth most common cause of cancer-related deaths in the world and 5-year overall survi …
24 results