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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
1993 8
1994 11
1995 12
1996 17
1997 14
1998 24
1999 14
2000 16
2001 27
2002 44
2003 52
2004 54
2005 60
2006 86
2007 88
2008 154
2009 212
2010 212
2011 284
2012 340
2013 373
2014 390
2015 403
2016 403
2017 405
2018 406
2019 425
2020 450
2021 385
2022 277
2023 271
2024 123

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5,269 results

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Page 1
WNT signaling and cancer stemness.
Katoh M, Katoh M. Katoh M, et al. Essays Biochem. 2022 Sep 16;66(4):319-331. doi: 10.1042/EBC20220016. Essays Biochem. 2022. PMID: 35837811 Free PMC article.
Cancer stemness, defined as the self-renewal and tumor-initiation potential of cancer stem cells (CSCs), is a cancer biology property featuring activation of CSC signaling networks. ...Noncanonical WNT signaling supports maintenance of slowly cycling, quiesce …
Cancer stemness, defined as the self-renewal and tumor-initiation potential of cancer stem cells (CSCs), is a cancer bi …
Multi-layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/beta-catenin signaling activation (Review).
Katoh M. Katoh M. Int J Mol Med. 2018 Aug;42(2):713-725. doi: 10.3892/ijmm.2018.3689. Epub 2018 May 17. Int J Mol Med. 2018. PMID: 29786110 Free PMC article. Review.
beta-catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion molecules (E-cadherin/CDH1, N-cadherin/CDH2, VE-cadherin/CDH5 and alpha-catenins), transmembrane-type mucins (MUC1/CD227 and MUC16/CA125), signaling regulators (APC, AXIN1, AXIN2 and NHERF1/EBP5 …
beta-catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion molecules (E-cadherin/CDH1, N-cadherin/CDH2, VE-cadher …
CCND1 Amplification in Breast Cancer -associations With Proliferation, Histopathological Grade, Molecular Subtype and Prognosis.
Valla M, Klæstad E, Ytterhus B, Bofin AM. Valla M, et al. J Mammary Gland Biol Neoplasia. 2022 Mar;27(1):67-77. doi: 10.1007/s10911-022-09516-8. Epub 2022 Apr 22. J Mammary Gland Biol Neoplasia. 2022. PMID: 35459982 Free PMC article.
CCND1 is located on 11q13. Increased CCND1 copy number (CN) in breast cancer (BC) is associated with high histopathological grade, high proliferation, and Luminal B subtype. ...Despite associations between high CCND1 CN and aggressive tumour characteri …
CCND1 is located on 11q13. Increased CCND1 copy number (CN) in breast cancer (BC) is associated with high histopatholog …
Identification of expression of CCND1-related lncRNAs in breast cancer.
Hussen BM, Hidayat HJ, Ghafouri-Fard S. Hussen BM, et al. Pathol Res Pract. 2022 Aug;236:154009. doi: 10.1016/j.prp.2022.154009. Epub 2022 Jul 1. Pathol Res Pract. 2022. PMID: 35803208
In the present two-step study, we first identified CCND1-related lncRNAs through an in silico approach. Then, we measured expression of CCND1 mRNA and five lncRNAs in paired breast cancer samples and their matched non-cancerous samples obtained from ad …
In the present two-step study, we first identified CCND1-related lncRNAs through an in silico approach. Then, we measured expression …
MIR497HG-Derived miR-195 and miR-497 Mediate Tamoxifen Resistance via PI3K/AKT Signaling in Breast Cancer.
Tian Y, Chen ZH, Wu P, Zhang D, Ma Y, Liu XF, Wang X, Ding D, Cao XC, Yu Y. Tian Y, et al. Adv Sci (Weinh). 2023 Apr;10(12):e2204819. doi: 10.1002/advs.202204819. Epub 2023 Feb 23. Adv Sci (Weinh). 2023. PMID: 36815359 Free PMC article.
Tamoxifen is commonly used for the treatment of patients with estrogen receptor-positive (ER+) breast cancer, but the acquired resistance to tamoxifen presents a critical challenge of breast cancer therapeutics. Recently, long noncoding RNA MIR497HG and its embedded …
Tamoxifen is commonly used for the treatment of patients with estrogen receptor-positive (ER+) breast cancer, but the acquired resist …
AURKB promotes gastric cancer progression via activation of CCND1 expression.
Nie M, Wang Y, Yu Z, Li X, Deng Y, Wang Y, Yang D, Li Q, Zeng X, Ju J, Liu M, Zhao Q. Nie M, et al. Aging (Albany NY). 2020 Jan 25;12(2):1304-1321. doi: 10.18632/aging.102684. Epub 2020 Jan 25. Aging (Albany NY). 2020. PMID: 31982864 Free PMC article.
We demonstrate that cyclin D1 (CCND1) is a direct downstream target of AURKB that plays a key role in gastric cancer cell proliferation. ...Importantly, we found that high AURKB and CCND1 expression levels are correlated with shorter overall survival of gastr …
We demonstrate that cyclin D1 (CCND1) is a direct downstream target of AURKB that plays a key role in gastric cancer cell prol …
CCND1-Induced Autophagy Contributes to Lymph Node Metastasis in Endometrial Cancer.
Su Y, Zhou H, Ma Z, Liu J, Li C. Su Y, et al. Horm Metab Res. 2023 Jun;55(6):413-419. doi: 10.1055/a-2044-9227. Epub 2023 Apr 5. Horm Metab Res. 2023. PMID: 37019147
CCND1 was overexpressed in endometrial cancer and correlated with lymph node metastasis. ...CCND1 promoted autophagy may contribute to lymph node metastasis in endometrial cancer....
CCND1 was overexpressed in endometrial cancer and correlated with lymph node metastasis. ...CCND1 promoted autophagy ma …
MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes.
Liu Y, Zhang A, Bao PP, Lin L, Wang Y, Wu H, Shu XO, Liu A, Cai Q. Liu Y, et al. Carcinogenesis. 2021 Apr 30;42(4):528-536. doi: 10.1093/carcin/bgab005. Carcinogenesis. 2021. PMID: 33480984 Free PMC article.
We further confirmed that CCND1 and TGFA contribute to the malignant behavior of breast cancer cells in vitro and in vivo. ...Taken together, our studies suggest that miR-374b modulates malignant behavior of breast cancer cells by negatively regulating CCN …
We further confirmed that CCND1 and TGFA contribute to the malignant behavior of breast cancer cells in vitro and in vivo. ... …
A study of CCND1 with epithelial ovarian cancer cell proliferation and apoptosis.
Dai J, Wei RJ, Li R, Feng JB, Yu YL, Liu PS. Dai J, et al. Eur Rev Med Pharmacol Sci. 2016 Oct;20(20):4230-4235. Eur Rev Med Pharmacol Sci. 2016. PMID: 27831653 Free article.
Markers for diagnosis, prognosis and therapy are urgently required to improve the mortality rates. As a key proto-oncogene, CCND1 is known to be amplified in many different carcinomas, including breast cancer, esophageal cancer, bladder cancer, endomet …
Markers for diagnosis, prognosis and therapy are urgently required to improve the mortality rates. As a key proto-oncogene, CCND1 is …
LncRNA NEAT1 accelerates breast cancer progression through regulating miR-410-3p/ CCND1 axis.
Liu X, Yao W, Xiong H, Li Q, Li Y. Liu X, et al. Cancer Biomark. 2020;29(2):277-290. doi: 10.3233/CBM-190721. Cancer Biomark. 2020. PMID: 32675392
In addition, NEAT1 regulated CCND1 expression by sponging miR-410-3p in breast cancer cells. NEAT1 knockdown blocked the tumor growth in vivo. CONCLUSION: NEAT1 induced breast cancer progression by regulating the miR-410-3p/CCND1 axis, indicating that …
In addition, NEAT1 regulated CCND1 expression by sponging miR-410-3p in breast cancer cells. NEAT1 knockdown blocked the tumor …
5,269 results