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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1995 1
1997 2
1998 2
1999 10
2000 9
2001 26
2002 26
2003 37
2004 53
2005 51
2006 70
2007 86
2008 108
2009 93
2010 149
2011 156
2012 187
2013 263
2014 268
2015 271
2016 453
2017 428
2018 446
2019 435
2020 427
2021 380
2022 276
2023 261
2024 124

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4,539 results

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Page 1
Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.
Hansford S, Kaurah P, Li-Chang H, Woo M, Senz J, Pinheiro H, Schrader KA, Schaeffer DF, Shumansky K, Zogopoulos G, Santos TA, Claro I, Carvalho J, Nielsen C, Padilla S, Lum A, Talhouk A, Baker-Lange K, Richardson S, Lewis I, Lindor NM, Pennell E, MacMillan A, Fernandez B, Keller G, Lynch H, Shah SP, Guilford P, Gallinger S, Corso G, Roviello F, Caldas C, Oliveira C, Pharoah PD, Huntsman DG. Hansford S, et al. JAMA Oncol. 2015 Apr;1(1):23-32. doi: 10.1001/jamaoncol.2014.168. JAMA Oncol. 2015. PMID: 26182300 Free article.
IMPORTANCE: E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffuse gastric cancer (HDGC). ...MAIN OUTCOMES AND MEASURES: Accurate estimates of gastric and breast cancer risks in CDH1 m …
IMPORTANCE: E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffus …
Hereditary Diffuse Gastric Cancer Syndrome and the Role of CDH1: A Review.
Gamble LA, Heller T, Davis JL. Gamble LA, et al. JAMA Surg. 2021 Apr 1;156(4):387-392. doi: 10.1001/jamasurg.2020.6155. JAMA Surg. 2021. PMID: 33404644 Review.
IMPORTANCE: Inherited variants in the tumor suppressor gene CDH1 are associated with an increased risk of gastric and breast cancers. This review aims to address the most current topics in management of the hereditary diffuse gastric cancer syndrome attribute …
IMPORTANCE: Inherited variants in the tumor suppressor gene CDH1 are associated with an increased risk of gastric and breast cance …
CDH1 and hereditary diffuse gastric cancer: a narrative review.
Gregory SN, Davis JL. Gregory SN, et al. Chin Clin Oncol. 2023 Jun;12(3):25. doi: 10.21037/cco-23-36. Epub 2023 Jun 5. Chin Clin Oncol. 2023. PMID: 37303221 Free article. Review.
Due to the high prevalence of cancer in patients with CDH1 variants, early screening and prophylactic total gastrectomy (PTG) are recommended. ...By leveraging advanced models, continuing clinical trials, and improving clinical management of affected individuals, re …
Due to the high prevalence of cancer in patients with CDH1 variants, early screening and prophylactic total gastrectomy (PTG) …
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes.
Garcia-Pelaez J, Barbosa-Matos R, Lobo S, Dias A, Garrido L, Castedo S, Sousa S, Pinheiro H, Sousa L, Monteiro R, Maqueda JJ, Fernandes S, Carneiro F, Pinto N, Lemos C, Pinto C, Teixeira MR, Aretz S, Bajalica-Lagercrantz S, Balmaña J, Blatnik A, Benusiglio PR, Blanluet M, Bours V, Brems H, Brunet J, Calistri D, Capellá G, Carrera S, Colas C, Dahan K, de Putter R, Desseignés C, Domínguez-Garrido E, Egas C, Evans DG, Feret D, Fewings E, Fitzgerald RC, Coulet F, Garcia-Barcina M, Genuardi M, Golmard L, Hackmann K, Hanson H, Holinski-Feder E, Hüneburg R, Krajc M, Lagerstedt-Robinson K, Lázaro C, Ligtenberg MJL, Martínez-Bouzas C, Merino S, Michils G, Novaković S, Patiño-García A, Ranzani GN, Schröck E, Silva I, Silveira C, Soto JL, Spier I, Steinke-Lange V, Tedaldi G, Tejada MI, Woodward ER, Tischkowitz M, Hoogerbrugge N, Oliveira C. Garcia-Pelaez J, et al. Lancet Oncol. 2023 Jan;24(1):91-106. doi: 10.1016/S1470-2045(22)00643-X. Epub 2022 Nov 24. Lancet Oncol. 2023. PMID: 36436516 Free PMC article.
INTERPRETATION: CDH1 PV/LPVs were positively associated with HDGC-related phenotypes (lobular breast cancer, diffuse gastric cancer, and gastric cancer), and no evidence for a positive association with these phenotypes was found for CDH1 missens …
INTERPRETATION: CDH1 PV/LPVs were positively associated with HDGC-related phenotypes (lobular breast cancer, diffuse gastric …
CDH1 germline mutations in families with hereditary lobular breast cancer.
Girardi A, Magnoni F, Vicini E, Kouloura A, La Vecchia C, Veronesi P, Corso G. Girardi A, et al. Eur J Cancer Prev. 2022 May 1;31(3):274-278. doi: 10.1097/CEJ.0000000000000688. Eur J Cancer Prev. 2022. PMID: 33990097 Review.
Pathogenic CDH1 germline mutations are associated with lobular breast cancer in the so-called hereditary lobular breast cancer (HLBC) syndrome, without apparent correlation with the classic hereditary diffuse gastric cancer (HDGC). Recent international …
Pathogenic CDH1 germline mutations are associated with lobular breast cancer in the so-called hereditary lobular breast can …
Hereditary Diffuse Gastric Cancer.
Decourtye-Espiard L, Guilford P. Decourtye-Espiard L, et al. Gastroenterology. 2023 Apr;164(5):719-735. doi: 10.1053/j.gastro.2023.01.038. Epub 2023 Feb 4. Gastroenterology. 2023. PMID: 36740198 Review.
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome characterized by a high incidence of diffuse gastric cancer (DGC) and lobular breast cancer (LBC). HDGC is caused by germline mutations in 2 genes involved in the epithe …
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome characterized by a high incidence of diffus …
Pleiotropic cancer manifestations of germline CDH1 mutations: Risks and management.
Corso G. Corso G. J Surg Oncol. 2022 Jun;125(8):1326-1331. doi: 10.1002/jso.26847. Epub 2022 Mar 12. J Surg Oncol. 2022. PMID: 35277969 Free PMC article. Review.
Germline CDH1 defects are related with the development of multiple cancers due its pleiotropic nature. ...In this clinical review, we described the penetrance risks of gastric, breast, prostate, and colorectal cancers, in CDH1 carriers, within as well …
Germline CDH1 defects are related with the development of multiple cancers due its pleiotropic nature. ...In this clinical rev …
Histological types of breast cancer: how special are they?
Weigelt B, Geyer FC, Reis-Filho JS. Weigelt B, et al. Mol Oncol. 2010 Jun;4(3):192-208. doi: 10.1016/j.molonc.2010.04.004. Epub 2010 Apr 18. Mol Oncol. 2010. PMID: 20452298 Free PMC article. Review.
Owing to the relative rarity of special types of breast cancer, information about the biology and clinical behaviour of breast cancers conveyed by histological type has not been taken into account. Histological special types of breast cancer account for up to …
Owing to the relative rarity of special types of breast cancer, information about the biology and clinical behaviour of breast can …
Familial and hereditary gastric cancer, an overview.
Carneiro F. Carneiro F. Best Pract Res Clin Gastroenterol. 2022 Jun-Aug;58-59:101800. doi: 10.1016/j.bpg.2022.101800. Epub 2022 May 4. Best Pract Res Clin Gastroenterol. 2022. PMID: 35988963 Review.
There are three major hereditable syndromes that affect primarily the stomach: hereditary diffuse gastric cancer (HDGC), gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) and familial intestinal gastric cancer (FIGC). ...GAPPS is caused by germlin …
There are three major hereditable syndromes that affect primarily the stomach: hereditary diffuse gastric cancer (HDGC), gastric aden …
CDH1 pathogenic variants and cancer risk in an unselected patient population.
Bar-Mashiah A, Soper ER, Cullina S, Belbin GM, Kenny EE, Lucas AL, Abul-Husn NS. Bar-Mashiah A, et al. Fam Cancer. 2022 Apr;21(2):235-239. doi: 10.1007/s10689-021-00257-x. Epub 2021 Apr 22. Fam Cancer. 2022. PMID: 33886068 Free PMC article.
CDH1 pathogenic variants confer a markedly elevated lifetime risk of developing diffuse gastric cancer (DGC) and lobular breast cancer (LBC). ...Our findings suggest a low risk of DGC and LBC in unselected patients harboring a pathogenic variant in CDH1 …
CDH1 pathogenic variants confer a markedly elevated lifetime risk of developing diffuse gastric cancer (DGC) and lobular breas …
4,539 results