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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 2
1995 5
1996 27
1997 25
1998 48
1999 31
2000 45
2001 51
2002 54
2003 55
2004 79
2005 84
2006 57
2007 78
2008 90
2009 101
2010 112
2011 87
2012 83
2013 99
2014 91
2015 111
2016 89
2017 84
2018 85
2019 88
2020 78
2021 76
2022 54
2023 44
2024 18

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1,830 results

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Page 1
Genetic Association Between CDKN1B rs2066827 Polymorphism and Susceptibility to Cancer.
Lu Y, Gao K, Zhang M, Zhou A, Zhou X, Guan Z, Shi X, Ge S. Lu Y, et al. Medicine (Baltimore). 2015 Nov;94(46):e1217. doi: 10.1097/MD.0000000000001217. Medicine (Baltimore). 2015. PMID: 26579796 Free PMC article. Review.
Much attention has been directed to the association between cancer risk and rs2066827 polymorphism of the CDKN1B gene. However, the results are indefinitive and inconclusive. ...TT).These data suggest that carriage of a TG genotype at rs2066827 polymorphism may be a …
Much attention has been directed to the association between cancer risk and rs2066827 polymorphism of the CDKN1B gene. However …
Roles of CDKN1B in cancer?
Belletti B, Baldassarre G. Belletti B, et al. Aging (Albany NY). 2015 Aug;7(8):529-30. doi: 10.18632/aging.100786. Aging (Albany NY). 2015. PMID: 26298275 Free PMC article. No abstract available.
The role of Skp2 and its substrate CDKN1B (p27) in colorectal cancer.
Bochis OV, Irimie A, Pichler M, Berindan-Neagoe I. Bochis OV, et al. J Gastrointestin Liver Dis. 2015 Jun;24(2):225-34. doi: 10.15403/jgld.2014.1121.242.skp2. J Gastrointestin Liver Dis. 2015. PMID: 26114183 Free article. Review.
Colorectal cancer is one of the most frequent cancers worldwide, having the fourth mortality rate among cancers in both sexes. ...The best known protein substrate of the Skp2 is the cyclin-dependent kinase inhibitor 1B (CDKN1B), also known as p27Kip1. …
Colorectal cancer is one of the most frequent cancers worldwide, having the fourth mortality rate among cancers in both …
YTHDF2 promotes intrahepatic cholangiocarcinoma progression and desensitises cisplatin treatment by increasing CDKN1B mRNA degradation.
Huang CS, Zhu YQ, Xu QC, Chen S, Huang Y, Zhao G, Ni X, Liu B, Zhao W, Yin XY. Huang CS, et al. Clin Transl Med. 2022 Jun;12(6):e848. doi: 10.1002/ctm2.848. Clin Transl Med. 2022. PMID: 35696608 Free PMC article.
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer with exceedingly poor prognosis, and chemoresistance is a huge challenge for treatment. ...Integration analysis using RNA-seq, MeRIP-seq and anti-YTHDF2 RIP-seq elucidated the role of YTHDF2 in tumou …
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer with exceedingly poor prognosis, and chemoresistance is a h …
CDKN1B mutation and copy number variation are associated with tumor aggressiveness in luminal breast cancer.
Viotto D, Russo F, Anania I, Segatto I, Rampioni Vinciguerra GL, Dall'Acqua A, Bomben R, Perin T, Cusan M, Schiappacassi M, Gerratana L, D'Andrea S, Citron F, Vit F, Musco L, Mattevi MC, Mungo G, Nicoloso MS, Sonego M, Massarut S, Sorio R, Barzan L, Franchin G, Giorda G, Lucia E, Sulfaro S, Giacomarra V, Polesel J, Toffolutti F, Canzonieri V, Puglisi F, Gattei V, Vecchione A, Belletti B, Baldassarre G. Viotto D, et al. J Pathol. 2021 Feb;253(2):234-245. doi: 10.1002/path.5584. Epub 2020 Dec 4. J Pathol. 2021. PMID: 33140857 Free PMC article.
Notwithstanding this effort, the mutation rate of CDKN1B remained substantially aligned with values from the literature, showing that essentially only hormone receptor-positive breast cancer displayed CDKN1B mutations in a relevant number of cases (3%). ...In …
Notwithstanding this effort, the mutation rate of CDKN1B remained substantially aligned with values from the literature, showing that …
miR-24 regulates CDKN1B/p27 expression in prostate cancer.
Lynch SM, McKenna MM, Walsh CP, McKenna DJ. Lynch SM, et al. Prostate. 2016 May;76(7):637-48. doi: 10.1002/pros.23156. Epub 2016 Feb 5. Prostate. 2016. PMID: 26847530
BACKGROUND: MicroRNAs (miRNAs) are small, non-coding RNA molecules with an important role in cancer. In prostate cancer, several miRNAs are expressed abnormally suggesting they may be useful markers for diagnosis, prognosis, and potential therapeutic intervention in …
BACKGROUND: MicroRNAs (miRNAs) are small, non-coding RNA molecules with an important role in cancer. In prostate cancer, sever …
A cancer-associated CDKN1B mutation induces p27 phosphorylation on a novel residue: a new mechanism for tumor suppressor loss-of-function.
Bencivenga D, Stampone E, Aulitto A, Tramontano A, Barone C, Negri A, Roberti D, Perrotta S, Della Ragione F, Borriello A. Bencivenga D, et al. Mol Oncol. 2021 Apr;15(4):915-941. doi: 10.1002/1878-0261.12881. Epub 2021 Feb 6. Mol Oncol. 2021. PMID: 33316141 Free PMC article.
CDKN1B haploinsufficiency promotes the development of several human cancers. ...However, very few data exist on the mechanisms by which CDKN1B missense mutations facilitate carcinogenesis. Here, we report a functional study on a cancer-associated germi …
CDKN1B haploinsufficiency promotes the development of several human cancers. ...However, very few data exist on the mechanisms …
CDKN1B Val 109 Gly variant is not related to risk of prostate cancer.
Zhu L, Wang J, Yue C, Yuan W, Zhang W, Shi L, Mi Y, Wu X, Zhang LF, Zuo L. Zhu L, et al. J Cell Biochem. 2019 Oct;120(10):18346-18356. doi: 10.1002/jcb.29144. Epub 2019 Jun 30. J Cell Biochem. 2019. PMID: 31257659
Association between CDKN1B gene Val 109 Gly polymorphism and prostate cancer (PCa) susceptibility has been investigated in several studies but with inconsistent conclusions. ...No significant difference of OS or DFS time was indicated between the low and high expres …
Association between CDKN1B gene Val 109 Gly polymorphism and prostate cancer (PCa) susceptibility has been investigated in sev …
MEN4 and CDKN1B mutations: the latest of the MEN syndromes.
Alrezk R, Hannah-Shmouni F, Stratakis CA. Alrezk R, et al. Endocr Relat Cancer. 2017 Oct;24(10):T195-T208. doi: 10.1530/ERC-17-0243. Epub 2017 Aug 19. Endocr Relat Cancer. 2017. PMID: 28824003 Free PMC article. Review.
A novel MEN syndrome was discovered, initially in rats (MENX), and later in humans (MEN4), which is caused by germline mutations in the putative tumor suppressor CDKN1B The most common phenotype of the 19 established cases of MEN4 that have been described to date is PHPT f …
A novel MEN syndrome was discovered, initially in rats (MENX), and later in humans (MEN4), which is caused by germline mutations in the puta …
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle.
Lei Y, Xu X, Liu H, Chen L, Zhou H, Jiang J, Yang Y, Wu B. Lei Y, et al. Autophagy. 2021 Dec;17(12):4423-4441. doi: 10.1080/15548627.2021.1917948. Epub 2021 Apr 27. Autophagy. 2021. PMID: 33866937 Free PMC article.
Our results demonstrate that ARRB1 plays a critical role in HBV-related HCC via modulating autophagy and the CDKN1B-CDK2-CCNE1-E2F1 axis and indicate that ARRB1 may be a potential therapeutic target for HCC.Abbreviations: ARRB1: arrestin beta 1; ACTB: actin beta; AMPK: ade …
Our results demonstrate that ARRB1 plays a critical role in HBV-related HCC via modulating autophagy and the CDKN1B-CDK2-CCNE1-E2F1 a …
1,830 results