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The Study of the Expression of CGB1 and CGB2 in Human Cancer Tissues.
Białas P, Śliwa A, Szczerba A, Jankowska A. Białas P, et al. Genes (Basel). 2020 Sep 17;11(9):1082. doi: 10.3390/genes11091082. Genes (Basel). 2020. PMID: 32957442 Free PMC article.
The hormone-specific beta subunit is encoded by six allelic genes: CGB3, CGB5, CGB6, CGB7, CGB8, and CGB9, mapped to the 19q13.32 locus. This gene cluster also encompasses the CGB1 and CGB2 genes, which were originally considered to be pseudogenes, but as documented by sev …
The hormone-specific beta subunit is encoded by six allelic genes: CGB3, CGB5, CGB6, CGB7, CGB8, and CGB9, mapped to the 19q13.32 locus. Thi …
Human chorionic gonadotropin beta subunit genes CGB1 and CGB2 are transcriptionally active in ovarian cancer.
Kubiczak M, Walkowiak GP, Nowak-Markwitz E, Jankowska A. Kubiczak M, et al. Int J Mol Sci. 2013 Jun 17;14(6):12650-60. doi: 10.3390/ijms140612650. Int J Mol Sci. 2013. PMID: 23774837 Free PMC article.
CGB is encoded by a cluster of six genes, of which type II genes (CGB3/9, 5 and 8) have been shown to be upregulated in relation to type I genes (CGB6/7) in both placentas and tumors. Recent studies revealed that CGB1 and CGB2, originally considered as pseudogenes, might a …
CGB is encoded by a cluster of six genes, of which type II genes (CGB3/9, 5 and 8) have been shown to be upregulated in relation to type I g …
Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer.
Śliwa A, Kubiczak M, Szczerba A, Walkowiak G, Nowak-Markwitz E, Burczyńska B, Butler S, Iles R, Białas P, Jankowska A. Śliwa A, et al. BMC Cancer. 2019 Jul 30;19(1):746. doi: 10.1186/s12885-019-5960-2. BMC Cancer. 2019. PMID: 31362717 Free PMC article.
However, expression of CGB3-9 genes was shown to be significantly higher in malignant than healthy ovarian tissues. CGB1 and CGB2 transcripts were shown to be present in 20% of ovarian cancers, but were not detected in any of the control samples. ...CGB3-9 expressio …
However, expression of CGB3-9 genes was shown to be significantly higher in malignant than healthy ovarian tissues. CGB1 and CGB2 tra …
Cancer-Testis Antigens as New Candidate Diagnostic Biomarkers for Transitional Cell Carcinoma of Bladder.
Afsharpad M, Nowroozi MR, Mobasheri MB, Ayati M, Nekoohesh L, Saffari M, Zendehdel K, Modarressi MH. Afsharpad M, et al. Pathol Oncol Res. 2019 Jan;25(1):191-199. doi: 10.1007/s12253-017-0313-4. Epub 2017 Oct 20. Pathol Oncol Res. 2019. PMID: 29058301 Free article.
To evaluate the diagnostic potential of 23 candidate genes, belonging to a category of tumor-specific antigens known as cancer-testis antigens (CTAs), in transitional cell carcinoma (TCC) patients. ...Among the known CTAs only MAGEA3, MAGEB4, TSGA10, PIWIL2, OIP5, and ODF4 …
To evaluate the diagnostic potential of 23 candidate genes, belonging to a category of tumor-specific antigens known as cancer-testis …
Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGbeta.
Burczynska BB, Kobrouly L, Butler SA, Naase M, Iles RK. Burczynska BB, et al. Anticancer Res. 2014 May;34(5):2239-48. Anticancer Res. 2014. PMID: 24778026
BACKGROUND: Ectopic secretion of human chorionic gonadotrophin free beta (hCGbeta) by epithelial cancer is associated with aggressive tumors which more readily metastasize, possibly by acting as an autocrine anti-apoptotic agent. hCGbeta is encoded by six homologous CGB ge …
BACKGROUND: Ectopic secretion of human chorionic gonadotrophin free beta (hCGbeta) by epithelial cancer is associated with aggressive …