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Lnc-CLSTN2-1:1 Promotes Osteosarcoma Progression by Disrupting Redox Balance through PI3K/AKT Signaling Pathway.
Lin H, Wei X, Ye J, Chen J, Huang J, Wu T, Chen Z, Zeng Y, Peng L. Lin H, et al. J Cancer. 2024 Jan 12;15(5):1287-1298. doi: 10.7150/jca.91579. eCollection 2024. J Cancer. 2024. PMID: 38356713 Free PMC article.
The primary purpose of this investigation was to explore the biological effect of Lnc-CLSTN2-1:1 on OS and the potential processes involved. Materials and procedures: We selected differentially overexpressed Lnc-CLSTN2-1:1 from our laboratory's existing RNA sequence …
The primary purpose of this investigation was to explore the biological effect of Lnc-CLSTN2-1:1 on OS and the potential processes in …
Unravelling the role of long non-coding RNA - LINC01087 in breast cancer.
Tripathi R, Aier I, Chakraborty P, Varadwaj PK. Tripathi R, et al. Noncoding RNA Res. 2019 Dec 24;5(1):1-10. doi: 10.1016/j.ncrna.2019.12.002. eCollection 2020 Mar. Noncoding RNA Res. 2019. PMID: 31989062 Free PMC article.
Longest non-coding type of ncRNAs (lncRNAs) have been considered as critical factors for the development and progression of breast cancer. The aim of our study was to identify set of novel lncRNAs interacting with microRNAs (miRNAs) or proteins that were significantly dysr …
Longest non-coding type of ncRNAs (lncRNAs) have been considered as critical factors for the development and progression of breast cancer
CHANGES IN GENE EXPRESSION ASSOCIATED WITH NON-CANCER EFFECTS OF THE CHORNOBYL CLEAN-UP WORKERS IN THE REMOTE PERIOD AFTER EXPOSURE.
Ilienko IM, Bazyka DA, Golyarnyk NA, Zvarych LM, Shvayko LI, Bazyka KD. Ilienko IM, et al. Probl Radiac Med Radiobiol. 2020 Dec;25:456-477. doi: 10.33145/2304-8336-2020-25-456-477. Probl Radiac Med Radiobiol. 2020. PMID: 33361854 English, Ukrainian.
It was shown an increase in the expression of genes associated with apoptosis and kinase activity (BCL2, CLSTN2, CDKN2), immune inflammation (CSF2, IL1B, TNF) in Chornobyl clean-upworkers with BPP. ...CONCLUSIONS: Changes in the expression of genes, associated with the dev …
It was shown an increase in the expression of genes associated with apoptosis and kinase activity (BCL2, CLSTN2, CDKN2), immune infla …
Integrated Analysis of Distant Metastasis-Associated Genes and Potential Drugs in Colon Adenocarcinoma.
Wu M, Lou W, Lou M, Fu P, Yu XF. Wu M, et al. Front Oncol. 2020 Oct 23;10:576615. doi: 10.3389/fonc.2020.576615. eCollection 2020. Front Oncol. 2020. PMID: 33194689 Free PMC article.
This study aims to identify prognosis-related genes associated with distant metastasis and develop therapeutic strategies for COAD patients. Methods: Transcriptomic data from The Cancer Genome Atlas (TCGA; n = 514) cohort were analyzed as a discovery dataset. ...Results: A …
This study aims to identify prognosis-related genes associated with distant metastasis and develop therapeutic strategies for COAD patients. …
A Novel 16-Genes Signature Scoring System as Prognostic Model to Evaluate Survival Risk in Patients with Glioblastoma.
Yu Z, Du M, Lu L. Yu Z, et al. Biomedicines. 2022 Jan 29;10(2):317. doi: 10.3390/biomedicines10020317. Biomedicines. 2022. PMID: 35203526 Free PMC article.
We collected gene expression data and clinical information from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases. Cox regression analysis and LASSO-cox regression analysis were performed to get survival-related genes and establish the overall …
We collected gene expression data and clinical information from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) …
Deep RNA sequencing reveals the dynamic regulation of miRNA, lncRNAs, and mRNAs in osteosarcoma tumorigenesis and pulmonary metastasis.
Xie L, Yao Z, Zhang Y, Li D, Hu F, Liao Y, Zhou L, Zhou Y, Huang Z, He Z, Han L, Yang Y, Yang Z. Xie L, et al. Cell Death Dis. 2018 Jul 10;9(7):772. doi: 10.1038/s41419-018-0813-5. Cell Death Dis. 2018. PMID: 29991755 Free PMC article.
Based on these ceRNA networks and Venn diagram analysis, we obtained 3 DEmiRNAs, 15 DElncRNAs, and 100 DEmRNAs, and eight target pairs including miR-223-5p/(CLSTN2, AC009951.1, LINC01705, AC090673.1), miR-378b/(ALX4, IGSF3, SULF1), and miR-323b-3p/TGFBR3 were involved in b …
Based on these ceRNA networks and Venn diagram analysis, we obtained 3 DEmiRNAs, 15 DElncRNAs, and 100 DEmRNAs, and eight target pairs inclu …