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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 1
1995 3
1998 1
2000 3
2002 4
2003 1
2004 4
2005 4
2006 2
2007 3
2008 8
2009 8
2010 6
2011 10
2012 4
2013 6
2014 9
2015 16
2016 23
2017 18
2018 27
2019 37
2020 58
2021 48
2022 45
2023 57
2024 27

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386 results

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Page 1
Oncogenic collagen I homotrimers from cancer cells bind to alpha3beta1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer.
Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R. Chen Y, et al. Cancer Cell. 2022 Aug 8;40(8):818-834.e9. doi: 10.1016/j.ccell.2022.06.011. Epub 2022 Jul 21. Cancer Cell. 2022. PMID: 35868307 Free PMC article.
In contrast to normal type I collagen (Col1) heterotrimer (alpha1/alpha2/alpha1) produced by fibroblasts, pancreatic cancer cells specifically produce unique Col1 homotrimer (alpha1/alpha1/alpha1). Col1 homotrimer results from epigenetic suppression of the Col1a2 ge …
In contrast to normal type I collagen (Col1) heterotrimer (alpha1/alpha2/alpha1) produced by fibroblasts, pancreatic cancer cells spe …
Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer.
Ucaryilmaz Metin C, Ozcan G. Ucaryilmaz Metin C, et al. BMC Cancer. 2022 Jun 23;22(1):692. doi: 10.1186/s12885-022-09736-5. BMC Cancer. 2022. PMID: 35739492 Free PMC article.
BACKGROUND: Gastric cancer is one of the deadliest cancers, currently available therapies have limited success. ...Lastly, we conducted a database search for drugs targeting the signature genes. RESULTS: Our study revealed the COL1A1, COL1A2, COL3A1, COL5A1, …
BACKGROUND: Gastric cancer is one of the deadliest cancers, currently available therapies have limited success. ...Lastly, we …
Identification of key genes in colorectal cancer diagnosis by co-expression analysis weighted gene co-expression network analysis.
Mortezapour M, Tapak L, Bahreini F, Najafi R, Afshar S. Mortezapour M, et al. Comput Biol Med. 2023 May;157:106779. doi: 10.1016/j.compbiomed.2023.106779. Epub 2023 Mar 11. Comput Biol Med. 2023. PMID: 36931200
Among these eight hub genes, upregulation of MMP9, SERPINH1, COL1A2, COL5A2, COL1A1, SPARC, and COL5A1 in CRC was validated in other microarray and TCGA data. ...Furthermore, Ocriplasmin and Collagenase clostridium histolyticum could target COL1A1, COL1A2, COL5A1, a …
Among these eight hub genes, upregulation of MMP9, SERPINH1, COL1A2, COL5A2, COL1A1, SPARC, and COL5A1 in CRC was validated in other …
Retraction.
[No authors listed] [No authors listed] J Cell Biochem. 2021 Nov;122 Suppl 1:S102. doi: 10.1002/jcb.30082. Epub 2021 Jul 19. J Cell Biochem. 2021. PMID: 34288045
Retraction: "Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while promoting apoptosis through the PI3k-Akt signaling pathway," by Ran Ao, Lin Guan, Ying Wang, Jia-Ni Wang, J Cell Biochem. 2018; 4420-4434: T …
Retraction: "Silencing of COL1A2, COL6A3, and THBS2 inhibits gastric cancer cell proliferation, migration, and invasion while …
Osteogenesis Imperfecta.
Marini JC, Dang Do AN. Marini JC, et al. 2020 Jul 26. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. 2020 Jul 26. In: Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000–. PMID: 25905334 Free Books & Documents. Review.
The classical Sillence types of OI (types I-IV) with autosomal dominant inheritance comprise about 80-85% of cases and are caused by mutations in the genes that encode type I collagen, COL1A1 and COL1A2. These types encompass the full spectrum of OI severity, from perinata …
The classical Sillence types of OI (types I-IV) with autosomal dominant inheritance comprise about 80-85% of cases and are caused by mutatio …
Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer.
Yao G, Zhao K, Bao K, Li J. Yao G, et al. Open Med (Wars). 2022 Feb 17;17(1):329-340. doi: 10.1515/med-2022-0436. eCollection 2022. Open Med (Wars). 2022. PMID: 35274048 Free PMC article.
BACKGROUND: Radiotherapy-associated secondary cancer is an important issue for the treatment of breast cancer (BCa). ...Sixteen DEGs, including three collagen genes collagen type I alpha 1 chain (COL1A1), COL3A1, and COL1A2, were enriched in 17 radiation-asso …
BACKGROUND: Radiotherapy-associated secondary cancer is an important issue for the treatment of breast cancer (BCa). ...Sixtee …
Transcriptomic Signatures in Colorectal Cancer Progression.
Ershov P, Poyarkov S, Konstantinova Y, Veselovsky E, Makarova A. Ershov P, et al. Curr Mol Med. 2023;23(3):239-249. doi: 10.2174/1566524022666220427102048. Curr Mol Med. 2023. PMID: 35490318 Review.
AIMS: Due to a large number of identified hub-genes encoding key molecular regulators, which are involved in signal transduction and metabolic pathways in cancers, it is relevant to systemize and update these findings. BACKGROUND: Colorectal cancer (CRC) is the thir …
AIMS: Due to a large number of identified hub-genes encoding key molecular regulators, which are involved in signal transduction and metabol …
The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion.
Yu Y, Liu D, Liu Z, Li S, Ge Y, Sun W, Liu B. Yu Y, et al. J Cancer. 2018 Jul 30;9(16):2953-2962. doi: 10.7150/jca.25542. eCollection 2018. J Cancer. 2018. PMID: 30123364 Free PMC article.
However, the role of COL1A2 in human colorectal cancer (CRC) remains unknown. This study investigated the expression pattern of COL1A2 in primary CRC tissues as well as the correlation of COL1A2 expression with clinicopathological features and prognosi …
However, the role of COL1A2 in human colorectal cancer (CRC) remains unknown. This study investigated the expression pattern o …
TWIST1-EP300 Expedites Gastric Cancer Cell Resistance to Apatinib by Activating the Expression of COL1A2.
Yu G, Chen W, Li X, Yu L, Xu Y, Ruan Q, He Y, Wang Y. Yu G, et al. Anal Cell Pathol (Amst). 2022 Feb 22;2022:5374262. doi: 10.1155/2022/5374262. eCollection 2022. Anal Cell Pathol (Amst). 2022. PMID: 35242497 Free PMC article.
The association between collagen type I alpha (COL1A) and chemoresistance has been verified in cancers. However, the specific role of COL1A2 in gastric cancer (GC) cell resistance to apatinib, a highly selective small-molecule inhibitor of vascular endothelia …
The association between collagen type I alpha (COL1A) and chemoresistance has been verified in cancers. However, the specific role of …
A feature-based analysis identifies COL1A2 as a regulator in pancreatic cancer.
Wu J, Liu J, Wei X, Yu Q, Niu X, Tang S, Song L. Wu J, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):420-428. doi: 10.1080/14756366.2018.1484734. J Enzyme Inhib Med Chem. 2019. PMID: 30734598 Free PMC article.
The expression of COL1A2 was determined by qRT-PCR; cell proliferation was determined by MTT assay; migration and invasion after COL1A2 and miR-25-3p transfection was evaluated by Transwell assay. COL1A2 presented the highest expression in PC tissues, which w …
The expression of COL1A2 was determined by qRT-PCR; cell proliferation was determined by MTT assay; migration and invasion after C …
386 results