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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 2
1999 1
2000 2
2001 4
2002 7
2003 8
2004 24
2005 35
2006 58
2007 73
2008 84
2009 74
2010 100
2011 85
2012 104
2013 121
2014 117
2015 79
2016 67
2017 62
2018 59
2019 47
2020 43
2021 43
2022 26
2023 11
2024 8

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1,116 results

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COMT Val158Met and PPARgamma Pro12Ala polymorphisms and susceptibility to Alzheimer's disease: a meta-analysis.
Lee YH, Song GG. Lee YH, et al. Neurol Sci. 2014 May;35(5):643-51. doi: 10.1007/s10072-014-1645-4. Epub 2014 Jan 30. Neurol Sci. 2014. PMID: 24477323 Review.
We conducted a meta-analysis of the associations between the COMT Val158Met and the PPARgamma Pro12Ala polymorphisms and AD in subjects. ...This meta-analysis identified an association between AD and the COMT Val158Met polymorphism in Asi …
We conducted a meta-analysis of the associations between the COMT Val158Met and the PPARgamma Pro12Ala polymorphisms an …
Are COMT Val158Met (rs4680), DRD2 TaqIA (rs1800497), and BDNF Val66Met (rs6265) polymorphisms associated with executive functions performance at rest and during physical exercise?
Frois T, Faria LO, Souza RP, da Silva Cunha AE, de Holanda Marinho Nogueira NG, Tavares Lim V, de Sousa Fortes L, de Miranda DM, Bertollo M, Albuquerque MR. Frois T, et al. Physiol Behav. 2022 Dec 1;257:113973. doi: 10.1016/j.physbeh.2022.113973. Epub 2022 Sep 28. Physiol Behav. 2022. PMID: 36179810 Free article.
Executive functions (EFs) encompass a wide array of cognitive processes, which appear to be influenced by genetic variants of the COMT, DRD2/ANKK1, and BDNF polymorphisms. The present study aimed to investigate whether COMT Val158Met (rs4680), D …
Executive functions (EFs) encompass a wide array of cognitive processes, which appear to be influenced by genetic variants of the …
Effects of DRD2/ANKK1 and COMT Val158Met polymorphisms on stabilization against and adaptation to unexpected events.
Trempler I, Binder E, Reuter M, Plieger T, Standke I, Mecklenbrauck F, Meinert S, Forstner AJ, Nöthen MM, Rietschel M, Stürmer S, Dannlowski U, Tittgemeyer M, Lencer R, Fink GR, Schubotz RI. Trempler I, et al. Cereb Cortex. 2022 Dec 8;32(24):5698-5715. doi: 10.1093/cercor/bhac046. Cereb Cortex. 2022. PMID: 35235645
Genetic variations affecting dopaminergic neuromodulation such as the DRD2/ANKK1 and the COMT Val158Met polymorphisms contribute to goal-directed behavior that requires a balance between stabilization and updating of current states and behaviors. ...A …
Genetic variations affecting dopaminergic neuromodulation such as the DRD2/ANKK1 and the COMT Val158Met polymorphism …
The relationships among MAOA, COMT Val158Met, and 5-HTTLPR polymorphisms, newborn stress reactivity, and infant temperament.
Bajgarova Z, Bajgar A. Bajgarova Z, et al. Brain Behav. 2020 Feb;10(2):e01511. doi: 10.1002/brb3.1511. Epub 2019 Dec 29. Brain Behav. 2020. PMID: 31884721 Free PMC article.
METHODS: We therefore explore the relationship among 5-HTTLPR S/L, MAOA H/L, and COMT Val158Met polymorphisms, the stress reaction of newborn infants after a heel stick blood draw (measured by determining salivary cortisol at three time points), and temperame …
METHODS: We therefore explore the relationship among 5-HTTLPR S/L, MAOA H/L, and COMT Val158Met polymorphisms, the stre …
COMT val158met and 5-HTTLPR genetic polymorphisms moderate executive control in cannabis users.
Verdejo-García A, Fagundo AB, Cuenca A, Rodriguez J, Cuyás E, Langohr K, de Sola Llopis S, Civit E, Farré M, Peña-Casanova J, de la Torre R. Verdejo-García A, et al. Neuropsychopharmacology. 2013 Jul;38(8):1598-606. doi: 10.1038/npp.2013.59. Epub 2013 Feb 28. Neuropsychopharmacology. 2013. PMID: 23449176 Free PMC article.
The adverse effects of cannabis use on executive functions are still controversial, fostering the need for novel biomarkers able to unveil individual differences in the cognitive impact of cannabis consumption. Two common genetic polymorphisms have been linked to th …
The adverse effects of cannabis use on executive functions are still controversial, fostering the need for novel biomarkers able to unveil i …
COMT Val158Met and 5-HT1A-R -1019 C/G polymorphisms: effects on the negative symptom response to clozapine.
Bosia M, Lorenzi C, Pirovano A, Guglielmino C, Cocchi F, Spangaro M, Bramanti P, Smeraldi E, Cavallaro R. Bosia M, et al. Pharmacogenomics. 2015 Jan;16(1):35-44. doi: 10.2217/pgs.14.150. Pharmacogenomics. 2015. PMID: 25560469
We examined the COMT Val158Met polymorphism, which plays a key role in dopamine regulation at the prefrontal level, and the 5-HT1A-R -1019 C/G polymorphism, a target of clozapine activity involved in the interaction between the serotonin and dopamine s …
We examined the COMT Val158Met polymorphism, which plays a key role in dopamine regulation at the prefrontal level, and …
BDNF 196 G/A and COMT Val158Met Polymorphisms and Susceptibility to ADHD: A Meta-Analysis.
Lee YH, Song GG. Lee YH, et al. J Atten Disord. 2018 Jul;22(9):872-877. doi: 10.1177/1087054715570389. Epub 2015 Feb 17. J Atten Disord. 2018. PMID: 25691534
OBJECTIVE: The aim of this study was to determine whether the brain-derived neurotrophic factor ( BDNF) 196 G/A or catechol- O-methyltransferase ( COMT) Val158Met polymorphisms is associated with susceptibility to ADHD. ...CONCLUSION: This meta-analysis showe …
OBJECTIVE: The aim of this study was to determine whether the brain-derived neurotrophic factor ( BDNF) 196 G/A or catechol- O-methyltransfe …
The effect of COMT Val158Met and DRD2 C957T polymorphisms on executive function and the impact of early life stress.
Klaus K, Butler K, Durrant SJ, Ali M, Inglehearn CF, Hodgson TL, Gutierrez H, Pennington K. Klaus K, et al. Brain Behav. 2017 Apr 12;7(5):e00695. doi: 10.1002/brb3.695. eCollection 2017 May. Brain Behav. 2017. PMID: 28523234 Free PMC article.
However, increasing evidence suggests environmental factors such as early life stress may interact with genetic variants in affecting these cognitive outcomes. This study investigated the effect of COMT Val158Met and DRD2 C957T polymorphisms on executi …
However, increasing evidence suggests environmental factors such as early life stress may interact with genetic variants in affecting …
Association of COMT val158met and DRD2 G>T genetic polymorphisms with individual differences in motor learning and performance in female young adults.
Noohi F, Boyden NB, Kwak Y, Humfleet J, Burke DT, Müller ML, Bohnen NI, Seidler RD. Noohi F, et al. J Neurophysiol. 2014 Feb;111(3):628-40. doi: 10.1152/jn.00457.2013. Epub 2013 Nov 13. J Neurophysiol. 2014. PMID: 24225542 Free PMC article.
Given the involvement of corticostriatal pathways in some types of learning, variations in dopaminergic transmission may contribute to these individual differences. Genetic polymorphisms of the catechol-O-methyltransferase (COMT) enzyme and dopamine receptor …
Given the involvement of corticostriatal pathways in some types of learning, variations in dopaminergic transmission may contribute to these …
The interactive effect of genetic polymorphisms of IL-10 and COMT on cognitive function in schizophrenia.
Wang J, Xu H, Wang D, Wei G, Zhou H, Wang L, Zhou Y, Zhang X. Wang J, et al. J Psychiatr Res. 2021 Apr;136:501-507. doi: 10.1016/j.jpsychires.2020.10.021. Epub 2020 Oct 22. J Psychiatr Res. 2021. PMID: 33127070
However, the interactive effect of their genetic polymorphisms has not been investigated. In this study, COMT Val158Met (rs4680) and IL-10 -592A/C (rs1800872) polymorphisms were measured in patients with chronic schizophrenia (n = 244) and healt …
However, the interactive effect of their genetic polymorphisms has not been investigated. In this study, COMT Val158 …
1,116 results