Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 2
2006 2
2007 3
2008 1
2009 2
2011 2
2012 5
2013 6
2014 5
2015 5
2016 3
2017 10
2018 8
2019 5
2020 10
2021 15
2022 11
2023 10
2024 8

Text availability

Article attribute

Article type

Publication date

Search Results

98 results

Results by year

Filters applied: . Clear all
Page 1
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
Pan Z, Xu T, Bao L, Hu X, Jin T, Chen J, Chen J, Qian Y, Lu X, Li L, Zheng G, Zhang Y, Zou X, Song F, Zheng C, Jiang L, Wang J, Tan Z, Huang P, Ge M. Pan Z, et al. Mol Cancer. 2022 Oct 3;21(1):190. doi: 10.1186/s12943-022-01658-x. Mol Cancer. 2022. PMID: 36192735 Free PMC article.
We screened for the CREB3 transcription-factor family in a large cohort, consisting of four microarray datasets. This revealed that CREB3L1 was specifically up regulated in ATC tissues and negatively associated with overall survival of patients with thyroid cancer. …
We screened for the CREB3 transcription-factor family in a large cohort, consisting of four microarray datasets. This revealed that CREB3 …
Pan-cancer analysis of CREB3L1 as biomarker in the prediction of prognosis and immunotherapeutic efficacy.
Lin Z, Wu Y, Xiao X, Zhang X, Wan J, Zheng T, Chen H, Liu T, Tang X. Lin Z, et al. Front Genet. 2022 Sep 9;13:938510. doi: 10.3389/fgene.2022.938510. eCollection 2022. Front Genet. 2022. PMID: 36171879 Free PMC article.
However, a systematic assessment of CREB3L1 in pan-cancer is of absence, and the predictive value of CREB3L1 in cancer prognosis, the tumor immune microenvironment and the efficacy of immunotherapy remains unexplored. Methods: CREB3L1 expression …
However, a systematic assessment of CREB3L1 in pan-cancer is of absence, and the predictive value of CREB3L1 in canc …
Characterizing dedifferentiation of thyroid cancer by integrated analysis.
Luo H, Xia X, Kim GD, Liu Y, Xue Z, Zhang L, Shu Y, Yang T, Chen Y, Zhang S, Chen H, Zhang W, Li R, Tang H, Dong B, Fu X, Cheng W, Zhang W, Yang L, Peng Y, Dai L, Hu H, Jiang Y, Gong C, Hu Y, Zhu J, Li Z, Caulin C, Wei T, Park J, Xu H. Luo H, et al. Sci Adv. 2021 Jul 28;7(31):eabf3657. doi: 10.1126/sciadv.abf3657. Print 2021 Jul. Sci Adv. 2021. PMID: 34321197 Free PMC article.
The developmental trajectory indicated that anaplastic thyroid cancer (ATC) cells were derived from a small subset of papillary thyroid cancer (PTC) cells. ...Collectively, our study provided insights into the heterogeneity and molecular evolution of thyroid canc …
The developmental trajectory indicated that anaplastic thyroid cancer (ATC) cells were derived from a small subset of papillary thyro …
Reduced CREB3L1 expression in triple negative and luminal a breast cancer cells contributes to enhanced cell migration, anchorage-independent growth and metastasis.
Mellor P, Kendall S, Smith S, Saxena A, Anderson DH. Mellor P, et al. PLoS One. 2022 Jul 8;17(7):e0271090. doi: 10.1371/journal.pone.0271090. eCollection 2022. PLoS One. 2022. PMID: 35802566 Free PMC article.
In this report, we set out to determine the expression level of CREB3L1 across different human breast cancer subtypes and determine whether CREB3L1 functions as a metastasis suppressor, particularly in triple negative breast cancers (TNBCs). ...Two lum …
In this report, we set out to determine the expression level of CREB3L1 across different human breast cancer subtypes and dete …
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.
Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB. Feng YX, et al. Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y. Nat Commun. 2017. PMID: 29057869 Free PMC article.
CREB3L1 acts downstream of PERK, specifically in the mesenchymal subtype of triple-negative tumors, and its inhibition by genetic or pharmacological methods suppresses cancer cell invasion and metastasis. In patients with this tumor subtype, CREB3L1 expressio …
CREB3L1 acts downstream of PERK, specifically in the mesenchymal subtype of triple-negative tumors, and its inhibition by genetic or …
CREB3L1 as a potential biomarker predicting response of triple negative breast cancer to doxorubicin-based chemotherapy.
Denard B, Jiang S, Peng Y, Ye J. Denard B, et al. BMC Cancer. 2018 Aug 13;18(1):813. doi: 10.1186/s12885-018-4724-8. BMC Cancer. 2018. PMID: 30103710 Free PMC article.
We have demonstrated that doxorubicin inhibits proliferation of cancer cells through proteolytic activation of a transcription factor called CREB3L1 (cAMP response element binding protein 3-like 1), and that CREB3L1 expression in cancer cells is a key …
We have demonstrated that doxorubicin inhibits proliferation of cancer cells through proteolytic activation of a transcription factor …
Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma.
Song G, Shi Y, Meng L, Ma J, Huang S, Zhang J, Wu Y, Li J, Lin Y, Yang S, Rao D, Cheng Y, Lin J, Ji S, Liu Y, Jiang S, Wang X, Zhang S, Ke A, Wang X, Cao Y, Ji Y, Zhou J, Fan J, Zhang X, Xi R, Gao Q. Song G, et al. Nat Commun. 2022 Mar 28;13(1):1642. doi: 10.1038/s41467-022-29164-0. Nat Commun. 2022. PMID: 35347134 Free PMC article.
Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. ...S100P + SPP1- iCCA(phl) has significantly reduced levels of infiltrating CD4(+) T cells, CD56(+) NK cells, and increased …
Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor mi …
OASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro.
Rose M, Schubert C, Dierichs L, Gaisa NT, Heer M, Heidenreich A, Knüchel R, Dahl E. Rose M, et al. Epigenetics. 2014 Dec;9(12):1626-40. doi: 10.4161/15592294.2014.988052. Epigenetics. 2014. PMID: 25625847 Free PMC article.
CREB3L1 has been recently proposed as a novel metastasis suppressor gene in breast cancer. Our current study highlights CREB3L1 expression, regulation, and function in bladder cancer. We demonstrate a significant downregulation of CREB3L1 mRNA e …
CREB3L1 has been recently proposed as a novel metastasis suppressor gene in breast cancer. Our current study highlights CRE …
Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1.
Denard B, Lee C, Ye J. Denard B, et al. Elife. 2012 Dec 18;1:e00090. doi: 10.7554/eLife.00090. Elife. 2012. PMID: 23256041 Free PMC article.
Knockdown of CREB3L1 mRNA in human hepatoma Huh7 cells and immortalized human fibroblast SV589 cells conferred increased resistance to doxorubicin, whereas overexpression of CREB3L1 in human breast cancer MCF-7 cells markedly enhanced the sensitivity of these …
Knockdown of CREB3L1 mRNA in human hepatoma Huh7 cells and immortalized human fibroblast SV589 cells conferred increased resistance t …
Induction of cell death in ovarian cancer cells by doxorubicin and oncolytic vaccinia virus is associated with CREB3L1 activation.
Mistarz A, Graczyk M, Winkler M, Singh PK, Cortes E, Miliotto A, Liu S, Long M, Yan L, Stablewski A, O'Loughlin K, Minderman H, Odunsi K, Rokita H, McGray AJR, Zsiros E, Kozbor D. Mistarz A, et al. Mol Ther Oncolytics. 2021 Apr 29;23:38-50. doi: 10.1016/j.omto.2021.04.014. eCollection 2021 Dec 17. Mol Ther Oncolytics. 2021. PMID: 34632049 Free PMC article.
This combination treatment was also effective in mediating nuclear translocation of CREB3L1 in cancer cells isolated from ovarian tumor biopsies at different stages of disease progression. The measurement of CREB3L1 expression in clinical specimens of ovarian …
This combination treatment was also effective in mediating nuclear translocation of CREB3L1 in cancer cells isolated from ovar …
98 results