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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 7
1994 11
1995 17
1996 26
1997 67
1998 91
1999 168
2000 174
2001 267
2002 300
2003 326
2004 340
2005 256
2006 51
2007 86
2008 117
2009 122
2010 141
2011 230
2012 249
2013 264
2014 372
2015 434
2016 461
2017 426
2018 561
2019 667
2020 689
2021 605
2022 377
2023 323
2024 147

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7,521 results

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Page 1
ACLY facilitates colon cancer cell metastasis by CTNNB1.
Wen J, Min X, Shen M, Hua Q, Han Y, Zhao L, Liu L, Huang G, Liu J, Zhao X. Wen J, et al. J Exp Clin Cancer Res. 2019 Sep 12;38(1):401. doi: 10.1186/s13046-019-1391-9. J Exp Clin Cancer Res. 2019. PMID: 31511060 Free PMC article.
We analyzed the correlation between ACLY and CTNNB1 protein in 78 colon cancer patients by Pearson correlation. ...Immunohistochemical analysis of 78 colon cancer patients showed that the high expression levels of ACLY and CTNNB1 protein was positively …
We analyzed the correlation between ACLY and CTNNB1 protein in 78 colon cancer patients by Pearson correlation. ...Immunohisto …
The Role of CTNNB1 in Endometrial Cancer.
Ledinek Ž, Sobočan M, Knez J. Ledinek Ž, et al. Dis Markers. 2022 Apr 28;2022:1442441. doi: 10.1155/2022/1442441. eCollection 2022. Dis Markers. 2022. PMID: 35531470 Free PMC article. Review.
Endometrial cancer (EC) is the most common gynaecologic malignancy in the developed countries. ...This could be improved by novel markers. One of such are mutations in the beta-catenin (CTNNB1) gene, a frequently mutated gene in endometrial cancer. This shows …
Endometrial cancer (EC) is the most common gynaecologic malignancy in the developed countries. ...This could be improved by novel mar …
Multi-layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/beta-catenin signaling activation (Review).
Katoh M. Katoh M. Int J Mol Med. 2018 Aug;42(2):713-725. doi: 10.3892/ijmm.2018.3689. Epub 2018 May 17. Int J Mol Med. 2018. PMID: 29786110 Free PMC article. Review.
Gain-of-function CTTNB1 mutations are detected in bladder cancer, colorectal cancer, gastric cancer, liver cancer, lung cancer, pancreatic cancer, prostate cancer and uterine cancer, whereas loss-of-function CTNNB1 mu …
Gain-of-function CTTNB1 mutations are detected in bladder cancer, colorectal cancer, gastric cancer, liver cancer …
Inhibiting Wnt/beta-catenin in CTNNB1-mutated endometrial cancer.
Moroney MR, Woodruff E, Qamar L, Bradford AP, Wolsky R, Bitler BG, Corr BR. Moroney MR, et al. Mol Carcinog. 2021 Aug;60(8):511-523. doi: 10.1002/mc.23308. Epub 2021 May 26. Mol Carcinog. 2021. PMID: 34038589
In an analysis of the Cancer Genome Atlas, we confirmed that CTNNB1 mutations are enriched in recurrent low-risk EC and showed that aberrant Wnt/beta-catenin pathway activation is associated with recurrence. We studied CTNNB1-wildtype (HEC1B, Ishikawa) and …
In an analysis of the Cancer Genome Atlas, we confirmed that CTNNB1 mutations are enriched in recurrent low-risk EC and showed …
Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.
Yaeger R, Chatila WK, Lipsyc MD, Hechtman JF, Cercek A, Sanchez-Vega F, Jayakumaran G, Middha S, Zehir A, Donoghue MTA, You D, Viale A, Kemeny N, Segal NH, Stadler ZK, Varghese AM, Kundra R, Gao J, Syed A, Hyman DM, Vakiani E, Rosen N, Taylor BS, Ladanyi M, Berger MF, Solit DB, Shia J, Saltz L, Schultz N. Yaeger R, et al. Cancer Cell. 2018 Jan 8;33(1):125-136.e3. doi: 10.1016/j.ccell.2017.12.004. Cancer Cell. 2018. PMID: 29316426 Free PMC article.
Metastatic colorectal cancers (mCRCs) are clinically heterogeneous, but the genomic basis of this variability remains poorly understood. ...We identified splice alterations in intronic regions of APC and large in-frame deletions in CTNNB1, increasing oncogenic WNT p …
Metastatic colorectal cancers (mCRCs) are clinically heterogeneous, but the genomic basis of this variability remains poorly understo …
Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression.
Liu T, Fan MQ, Xie XX, Shu QP, Du XH, Qi LZ, Zhang XD, Zhang MH, Shan G, Du RL, Li SZ. Liu T, et al. J Transl Med. 2023 Sep 22;21(1):656. doi: 10.1186/s12967-023-04311-3. J Transl Med. 2023. PMID: 37740194 Free PMC article.
BACKGROUND: The catenin beta 1 gene (CTNNB1) plays a crucial role in the malignant progression of various cancers. Recent studies have suggested that CTNNB1 hyperactivation is closely related to the occurrence and development of bladder cancer (BCa). . …
BACKGROUND: The catenin beta 1 gene (CTNNB1) plays a crucial role in the malignant progression of various cancers. Recent stud …
Wnt/beta-catenin signaling in cancers and targeted therapies.
Yu F, Yu C, Li F, Zuo Y, Wang Y, Yao L, Wu C, Wang C, Ye L. Yu F, et al. Signal Transduct Target Ther. 2021 Aug 30;6(1):307. doi: 10.1038/s41392-021-00701-5. Signal Transduct Target Ther. 2021. PMID: 34456337 Free PMC article. Review.
Wnt/beta-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. Aberrant activation of Wnt/beta-catenin signaling is tightly linked with the increment of prevalence, advancement of malignant progression, development …
Wnt/beta-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. Aberrant ac …
lncRNA SNHG11 Promotes Gastric Cancer Progression by Activating the Wnt/beta-Catenin Pathway and Oncogenic Autophagy.
Wu Q, Ma J, Wei J, Meng W, Wang Y, Shi M. Wu Q, et al. Mol Ther. 2021 Mar 3;29(3):1258-1278. doi: 10.1016/j.ymthe.2020.10.011. Epub 2020 Oct 15. Mol Ther. 2021. PMID: 33068778 Free PMC article.
Long non-coding RNAs (lncRNAs) are under active investigation in the development of cancers, including gastric cancer (GC). Oncogenic autophagy is required for cancer cell survival. ...Mechanistically, SNHG11 post-transcriptionally upregulated catenin beta 1 …
Long non-coding RNAs (lncRNAs) are under active investigation in the development of cancers, including gastric cancer (GC). On …
Cis-Acting circ-CTNNB1 Promotes beta-Catenin Signaling and Cancer Progression via DDX3-Mediated Transactivation of YY1.
Yang F, Fang E, Mei H, Chen Y, Li H, Li D, Song H, Wang J, Hong M, Xiao W, Wang X, Huang K, Zheng L, Tong Q. Yang F, et al. Cancer Res. 2019 Feb 1;79(3):557-571. doi: 10.1158/0008-5472.CAN-18-1559. Epub 2018 Dec 18. Cancer Res. 2019. PMID: 30563889
Circ-CTNNB1 was predominantly expressed in the nucleus, upregulated in cancer tissues and cell lines, and associated with unfavorable outcomes in patients with cancer. Circ-CTNNB1 promoted beta-catenin activation, growth, invasion, and metastasis in …
Circ-CTNNB1 was predominantly expressed in the nucleus, upregulated in cancer tissues and cell lines, and associated with unfa …
WNT/beta-catenin signaling in the development of liver cancers.
He S, Tang S. He S, et al. Biomed Pharmacother. 2020 Dec;132:110851. doi: 10.1016/j.biopha.2020.110851. Epub 2020 Oct 17. Biomed Pharmacother. 2020. PMID: 33080466 Free article. Review.
Of note, accumulating evidence has shown that the aberrant of WNT/beta-catenin signaling promotes the development and/or progression of liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), the two most prevalent primary liver tumours in adul …
Of note, accumulating evidence has shown that the aberrant of WNT/beta-catenin signaling promotes the development and/or progression of live …
7,521 results