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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1997 2
1998 2
1999 7
2000 3
2001 5
2002 3
2003 10
2004 7
2005 6
2006 14
2007 17
2008 10
2009 11
2010 15
2011 7
2012 14
2013 15
2014 16
2015 17
2016 20
2017 22
2018 13
2019 15
2020 19
2021 17
2022 11
2023 6
2024 8

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277 results

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Page 1
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.
Yan HHN, Siu HC, Law S, Ho SL, Yue SSK, Tsui WY, Chan D, Chan AS, Ma S, Lam KO, Bartfeld S, Man AHY, Lee BCH, Chan ASY, Wong JWH, Cheng PSW, Chan AKW, Zhang J, Shi J, Fan X, Kwong DLW, Mak TW, Yuen ST, Clevers H, Leung SY. Yan HHN, et al. Cell Stem Cell. 2018 Dec 6;23(6):882-897.e11. doi: 10.1016/j.stem.2018.09.016. Epub 2018 Oct 18. Cell Stem Cell. 2018. PMID: 30344100 Free article.
Gastric cancer displays marked molecular heterogeneity with aggressive behavior and treatment resistance. ...Overall, this new GCO biobank, with linked genomic data, provides a useful resource for studying both cancer cell biology and precision cancer therapy …
Gastric cancer displays marked molecular heterogeneity with aggressive behavior and treatment resistance. ...Overall, this new GCO bi …
Silencing CTNND1 Mediates Triple-Negative Breast Cancer Bone Metastasis via Upregulating CXCR4/CXCL12 Axis and Neutrophils Infiltration in Bone.
Lin Q, Fang X, Liang G, Luo Q, Cen Y, Shi Y, Jia S, Li J, Yang W, Sanders AJ, Gong C, Jiang W. Lin Q, et al. Cancers (Basel). 2021 Nov 15;13(22):5703. doi: 10.3390/cancers13225703. Cancers (Basel). 2021. PMID: 34830862 Free PMC article.
Clinically, patients with triple-negative breast cancer and lower level of CTNND1 had shorter overall survival (OS) and distant metastasis-free survival (DMFS). It was concluded that downregulation of CTNND1 played a critical role in facilitating bone metasta …
Clinically, patients with triple-negative breast cancer and lower level of CTNND1 had shorter overall survival (OS) and distan …
Frequency of CDH1, CTNNA1 and CTNND1 Germline Variants in Families with Diffuse and Mixed Gastric Cancer.
Guerra J, Pinto C, Pinto P, Pinheiro M, Santos C, Peixoto A, Escudeiro C, Barbosa A, Porto M, Francisco I, Lopes P, Isidoro AR, Cunha AL, Albuquerque C, Claro I, Oliveira C, Silva J, Teixeira MR. Guerra J, et al. Cancers (Basel). 2023 Aug 29;15(17):4313. doi: 10.3390/cancers15174313. Cancers (Basel). 2023. PMID: 37686589 Free PMC article.
The most well-characterized hereditary form of gastric cancer is hereditary diffuse gastric cancer (HDGC), an autosomal dominant syndrome characterized by an increased risk of diffuse gastric and lobular breast cancer. ...The role of the CTNND1 gene in …
The most well-characterized hereditary form of gastric cancer is hereditary diffuse gastric cancer (HDGC), an autosomal domina …
The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level.
Kanoh T, Lu J, Mizoguchi T, Itoh M. Kanoh T, et al. Biochem Biophys Res Commun. 2023 Jul 30;667:73-80. doi: 10.1016/j.bbrc.2023.05.034. Epub 2023 May 11. Biochem Biophys Res Commun. 2023. PMID: 37209565
Breast cancer is one of the most common invasive cancers among women. The leading cause of difficulty in treating breast cancer patients is metastasis. ...We found that the downregulation of MIB1 promotes the cell migration of MCF7, a breast cancer-der …
Breast cancer is one of the most common invasive cancers among women. The leading cause of difficulty in treating breast ca …
CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions.
Herrera-Pariente C, Bonjoch L, Muñoz J, Fernàndez G, Soares de Lima Y, Mahmood R, Cuatrecasas M, Ocaña T, Lopez-Prades S, Llargués-Sistac G, Domínguez-Rovira X, Llach J, Luzko I, Díaz-Gay M, Lazaro C, Brunet J, Castillo-Manzano C, García-González MA, Lanas A, Carrillo M, Hernández San Gil R, Quintero E, Sala N, Llort G, Aguilera L, Carot L, Diez-Redondo P, Jover R, Ramon Y Cajal T, Cubiella J, Castells A, Balaguer F, Bujanda L, Castellví-Bel S, Moreira L. Herrera-Pariente C, et al. Gastric Cancer. 2024 May 25. doi: 10.1007/s10120-024-01504-7. Online ahead of print. Gastric Cancer. 2024. PMID: 38796558
BACKGROUND: CDH1 and CTNNA1 remain as the main genes for hereditary gastric cancer. However, they only explain a small fraction of gastric cancer cases with suspected inherited basis. ...(Pro369Ser) variant, located in a key region in the E-cadherin/p120ctn binding …
BACKGROUND: CDH1 and CTNNA1 remain as the main genes for hereditary gastric cancer. However, they only explain a small fraction of ga …
Overexpression of CTNND1 in hepatocellular carcinoma promotes carcinous characters through activation of Wnt/beta-catenin signaling.
Tang B, Tang F, Wang Z, Qi G, Liang X, Li B, Yuan S, Liu J, Yu S, He S. Tang B, et al. J Exp Clin Cancer Res. 2016 May 18;35(1):82. doi: 10.1186/s13046-016-0344-9. J Exp Clin Cancer Res. 2016. PMID: 27193094 Free PMC article.
In vivo metastasis assays were performed in SCID mice. RESULTS: In clinical HCC samples, we found that CTNND1 expression was significantly up-regulated in cancer lesions compared with paired normal liver tissues. By silencing or overexpressing CTNND1 in HCC c …
In vivo metastasis assays were performed in SCID mice. RESULTS: In clinical HCC samples, we found that CTNND1 expression was signific …
Role of epithelial splicing regulatory protein 1 in cancer progression.
Kwon MJ. Kwon MJ. Cancer Cell Int. 2023 Dec 18;23(1):331. doi: 10.1186/s12935-023-03180-6. Cancer Cell Int. 2023. PMID: 38110955 Free PMC article. Review.
However, ESRP1 has been found to promote cancer progression in some cancers, such as breast and ovarian cancers, indicating that it plays a dual role in cancer progression depending on the type of cancer. ...This review describes current underst …
However, ESRP1 has been found to promote cancer progression in some cancers, such as breast and ovarian cancers, indica …
Catenin-delta1, negatively regulated by miR-145, promotes tumour aggressiveness in gastric cancer.
Xing AY, Wang YW, Su ZX, Shi DB, Wang B, Gao P. Xing AY, et al. J Pathol. 2015 May;236(1):53-64. doi: 10.1002/path.4495. Epub 2015 Jan 5. J Pathol. 2015. PMID: 25470111
Cell proliferation, apoptosis, migration and invasion assays were performed to assess the effect of CTNND1 cDNA or CTNND1 siRNA transfection on gastric cancer cells. ...We conclude that cytoplasmic CTNND1 can serve as an independent prognostic factor f …
Cell proliferation, apoptosis, migration and invasion assays were performed to assess the effect of CTNND1 cDNA or CTNND1 siRN …
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated beta-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y. Liu D, et al. Cell Cycle. 2020 Aug;19(15):1917-1927. doi: 10.1080/15384101.2020.1783058. Epub 2020 Jun 28. Cell Cycle. 2020. PMID: 32594834 Free PMC article.
Colorectal cancer (CRC) is a common malignancy with high mortality. However, the roles of miR-425-5p and its underlying mechanism in CRC remain unknown. ...Luciferase reporter assay indicated that miR-425-5p directly targeted CTNND1. Overexpression of miR-425-5p rep …
Colorectal cancer (CRC) is a common malignancy with high mortality. However, the roles of miR-425-5p and its underlying mechanism in …
277 results