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Galactosialidosis: preclinical enzyme replacement therapy in a mouse model of the disease, a proof of concept.
Mol Ther Methods Clin Dev. 2020 Nov 20;20:191-203. doi: 10.1016/j.omtm.2020.11.012. eCollection 2021 Mar 12.
Mol Ther Methods Clin Dev. 2020.
PMID: 33426146
Free PMC article.
Vestronidase alfa: Recombinant human β-glucuronidase as an enzyme replacement therapy for MPS VII.
Cadaoas J, Boyle G, Jungles S, Cullen S, Vellard M, Grubb JH, Jurecka A, Sly W, Kakkis E.
Cadaoas J, et al.
Mol Genet Metab. 2020 May;130(1):65-76. doi: 10.1016/j.ymgme.2020.02.009. Epub 2020 Mar 6.
Mol Genet Metab. 2020.
PMID: 32192868
Free article.
Clinical Trial.
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Conventional and Unconventional Therapeutic Strategies for Sialidosis Type I.
Mosca R, van de Vlekkert D, Campos Y, Fremuth LE, Cadaoas J, Koppaka V, Kakkis E, Tifft C, Toro C, Allievi S, Gellera C, Canafoglia L, Visser G, Annunziata I, d'Azzo A.
Mosca R, et al. Among authors: cadaoas j.
J Clin Med. 2020 Mar 4;9(3):695. doi: 10.3390/jcm9030695.
J Clin Med. 2020.
PMID: 32143456
Free PMC article.
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Tolerance induction and microglial engraftment after fetal therapy without conditioning in mice with Mucopolysaccharidosis type VII.
Nguyen QH, Witt RG, Wang B, Eikani C, Shea J, Smith LK, Boyle G, Cadaoas J, Sper R, MacKenzie JD, Villeda S, MacKenzie TC.
Nguyen QH, et al. Among authors: cadaoas j.
Sci Transl Med. 2020 Feb 26;12(532):eaay8980. doi: 10.1126/scitranslmed.aay8980.
Sci Transl Med. 2020.
PMID: 32102934
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Substantial deficiency of free sialic acid in muscles of patients with GNE myopathy and in a mouse model.
Chan YM, Lee P, Jungles S, Morris G, Cadaoas J, Skrinar A, Vellard M, Kakkis E.
Chan YM, et al. Among authors: cadaoas j.
PLoS One. 2017 Mar 7;12(3):e0173261. doi: 10.1371/journal.pone.0173261. eCollection 2017.
PLoS One. 2017.
PMID: 28267778
Free PMC article.
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Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells.
Fong S, Shoemaker M, Cadaoas J, Lo A, Liao W, Tagliaferri M, Cohen I, Shtivelman E.
Fong S, et al. Among authors: cadaoas j.
Cancer Biol Ther. 2008 Apr;7(4):577-86. doi: 10.4161/cbt.7.4.5535. Epub 2008 Jan 7.
Cancer Biol Ther. 2008.
PMID: 18305410
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Stimulation of B lymphocytes by cmvIL-10 but not LAcmvIL-10.
Spencer JV, Cadaoas J, Castillo PR, Saini V, Slobedman B.
Spencer JV, et al. Among authors: cadaoas j.
Virology. 2008 Apr 25;374(1):164-9. doi: 10.1016/j.virol.2007.11.031. Epub 2008 Jan 28.
Virology. 2008.
PMID: 18222515
Free PMC article.
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