Cagan RL - Search Results

1

Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network.

Ung PMU, Sonoshita M, Scopton AP, Dar AC, Cagan RL, Schlessinger A. Ung PMU, et al. Among authors: cagan rl. PLoS Comput Biol. 2019 Apr 26;15(4):e1006878. doi: 10.1371/journal.pcbi.1006878. eCollection 2019 Apr. PLoS Comput Biol. 2019. PMID: 31026276 Free PMC article.

2

Drosophila as a novel therapeutic discovery tool for thyroid cancer.

Das T, Cagan R. Das T, et al. Thyroid. 2010 Jul;20(7):689-95. doi: 10.1089/thy.2010.1637. Thyroid. 2010. PMID: 20578898 Review.

3

Drosophila cancer models.

Rudrapatna VA, Cagan RL, Das TK. Rudrapatna VA, et al. Among authors: cagan rl. Dev Dyn. 2012 Jan;241(1):107-18. doi: 10.1002/dvdy.22771. Epub 2011 Oct 28. Dev Dyn. 2012. PMID: 22038952 Free PMC article. Review.

4

Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.

Dar AC, Das TK, Shokat KM, Cagan RL. Dar AC, et al. Among authors: cagan rl. Nature. 2012 Jun 6;486(7401):80-4. doi: 10.1038/nature11127. Nature. 2012. PMID: 22678283 Free PMC article.

5

Drosophila Lung Cancer Models Identify Trametinib plus Statin as Candidate Therapeutic.

Levine BD, Cagan RL. Levine BD, et al. Among authors: cagan rl. Cell Rep. 2016 Feb 16;14(6):1477-1487. doi: 10.1016/j.celrep.2015.12.105. Epub 2016 Jan 28. Cell Rep. 2016. PMID: 26832408 Free PMC article.

6

Drosophila Cancer Models Identify Functional Differences between Ret Fusions.

Levinson S, Cagan RL. Levinson S, et al. Among authors: cagan rl. Cell Rep. 2016 Sep 13;16(11):3052-3061. doi: 10.1016/j.celrep.2016.08.019. Cell Rep. 2016. PMID: 27626672 Free PMC article.

7

Functional exploration of colorectal cancer genomes using Drosophila.

Bangi E, Murgia C, Teague AG, Sansom OJ, Cagan RL. Bangi E, et al. Among authors: cagan rl. Nat Commun. 2016 Nov 29;7:13615. doi: 10.1038/ncomms13615. Nat Commun. 2016. PMID: 27897178 Free PMC article.

8

Modeling Human Cancers in Drosophila.

Sonoshita M, Cagan RL. Sonoshita M, et al. Among authors: cagan rl. Curr Top Dev Biol. 2017;121:287-309. doi: 10.1016/bs.ctdb.2016.07.008. Epub 2016 Jul 30. Curr Top Dev Biol. 2017. PMID: 28057303 Review.

9

Multi-targeting Drug Community Challenge.

Schlessinger A, Abagyan R, Carlson HA, Dang KK, Guinney J, Cagan RL. Schlessinger A, et al. Among authors: cagan rl. Cell Chem Biol. 2017 Dec 21;24(12):1434-1435. doi: 10.1016/j.chembiol.2017.12.006. Cell Chem Biol. 2017. PMID: 29272700 Free article. No abstract available.

10

A whole-animal platform to advance a clinical kinase inhibitor into new disease space.

Sonoshita M, Scopton AP, Ung PMU, Murray MA, Silber L, Maldonado AY, Real A, Schlessinger A, Cagan RL, Dar AC. Sonoshita M, et al. Among authors: cagan rl. Nat Chem Biol. 2018 Mar;14(3):291-298. doi: 10.1038/nchembio.2556. Epub 2018 Jan 22. Nat Chem Biol. 2018. PMID: 29355849 Free PMC article.

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