Cai L - Search Results

1

Synthesis and structure-affinity relationships of new 4-(6-iodo-H-imidazo[1,2-a]pyridin-2-yl)-N-dimethylbenzeneamine derivatives as ligands for human beta-amyloid plaques.

Cai L, Cuevas J, Temme S, Herman MM, Dagostin C, Widdowson DA, Innis RB, Pike VW. Cai L, et al. J Med Chem. 2007 Sep 20;50(19):4746-58. doi: 10.1021/jm0702231. Epub 2007 Aug 28. J Med Chem. 2007. PMID: 17722900

2

Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease.

Cai L, Chin FT, Pike VW, Toyama H, Liow JS, Zoghbi SS, Modell K, Briard E, Shetty HU, Sinclair K, Donohue S, Tipre D, Kung MP, Dagostin C, Widdowson DA, Green M, Gao W, Herman MM, Ichise M, Innis RB. Cai L, et al. J Med Chem. 2004 Apr 22;47(9):2208-18. doi: 10.1021/jm030477w. J Med Chem. 2004. PMID: 15084119 Free PMC article.

3

PET imaging of brain with the beta-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer's disease.

Toyama H, Ye D, Ichise M, Liow JS, Cai L, Jacobowitz D, Musachio JL, Hong J, Crescenzo M, Tipre D, Lu JQ, Zoghbi S, Vines DC, Seidel J, Katada K, Green MV, Pike VW, Cohen RM, Innis RB. Toyama H, et al. Among authors: cai l. Eur J Nucl Med Mol Imaging. 2005 May;32(5):593-600. doi: 10.1007/s00259-005-1780-5. Epub 2005 Mar 25. Eur J Nucl Med Mol Imaging. 2005. PMID: 15791432

4

Imaging and in vivo quantitation of beta-amyloid: an exemplary biomarker for Alzheimer's disease?

Nichols L, Pike VW, Cai L, Innis RB. Nichols L, et al. Among authors: cai l. Biol Psychiatry. 2006 May 15;59(10):940-7. doi: 10.1016/j.biopsych.2005.12.004. Epub 2006 Feb 17. Biol Psychiatry. 2006. PMID: 16487944 Review.

5

Lipophilic analogs of thioflavin S as novel amyloid-imaging agents.

Wu C, Cai L, Wei J, Pike VW, Wang Y. Wu C, et al. Among authors: cai l. Curr Alzheimer Res. 2006 Jul;3(3):259-66. doi: 10.2174/156720506777632862. Curr Alzheimer Res. 2006. PMID: 16842103

6

Radioligand development for PET imaging of beta-amyloid (Abeta)--current status.

Cai L, Innis RB, Pike VW. Cai L, et al. Curr Med Chem. 2007;14(1):19-52. doi: 10.2174/092986707779313471. Curr Med Chem. 2007. PMID: 17266566

7

Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques.

Seneca N, Cai L, Liow JS, Zoghbi SS, Gladding RL, Hong J, Pike VW, Innis RB. Seneca N, et al. Among authors: cai l. Nucl Med Biol. 2007 Aug;34(6):681-9. doi: 10.1016/j.nucmedbio.2007.06.002. Nucl Med Biol. 2007. PMID: 17707808

8

Synthesis and evaluation of N-methyl and S-methyl 11C-labeled 6-methylthio-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as radioligands for imaging beta-amyloid plaques in Alzheimer's disease.

Cai L, Liow JS, Zoghbi SS, Cuevas J, Baetas C, Hong J, Shetty HU, Seneca NM, Brown AK, Gladding R, Temme SS, Herman MM, Innis RB, Pike VW. Cai L, et al. J Med Chem. 2008 Jan 10;51(1):148-58. doi: 10.1021/jm700970s. Epub 2007 Dec 14. J Med Chem. 2008. PMID: 18078311

9

Rapid Room-Temperature ¹¹C-Methylation of Arylamines with [¹¹C]Methyl Iodide Promoted by Solid Inorganic Bases in DMF.

Cai L, Xu R, Guo X, Pike VW. Cai L, et al. European J Org Chem. 2012 Mar;2012(7):1303-1310. doi: 10.1002/ejoc.201101499. European J Org Chem. 2012. PMID: 24659907 Free PMC article.

10

New N-aryl-N'-(3-(substituted)phenyl)-N'-methylguanidines as leads to potential PET radioligands for imaging the open NMDA receptor.

Naumiec GR, Cai L, Pike VW. Naumiec GR, et al. Among authors: cai l. Bioorg Med Chem Lett. 2015 Jan 15;25(2):225-8. doi: 10.1016/j.bmcl.2014.11.066. Epub 2014 Nov 29. Bioorg Med Chem Lett. 2015. PMID: 25499436 Free PMC article.

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