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Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein.
Zerbinatti CV, Wozniak DF, Cirrito J, Cam JA, Osaka H, Bales KR, Zhuo M, Paul SM, Holtzman DM, Bu G. Zerbinatti CV, et al. Among authors: cam ja. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1075-80. doi: 10.1073/pnas.0305803101. Epub 2004 Jan 19. Proc Natl Acad Sci U S A. 2004. PMID: 14732699 Free PMC article.
LRP in amyloid-beta production and metabolism.
Bu G, Cam J, Zerbinatti C. Bu G, et al. Ann N Y Acad Sci. 2006 Nov;1086:35-53. doi: 10.1196/annals.1377.005. Ann N Y Acad Sci. 2006. PMID: 17185504 Review.
ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.
Fuentealba RA, Barría MI, Lee J, Cam J, Araya C, Escudero CA, Inestrosa NC, Bronfman FC, Bu G, Marzolo MP. Fuentealba RA, et al. Mol Neurodegener. 2007 Jul 9;2:14. doi: 10.1186/1750-1326-2-14. Mol Neurodegener. 2007. PMID: 17620134 Free PMC article.
The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.
Snow AD, Castillo GM, Nguyen BP, Choi PY, Cummings JA, Cam J, Hu Q, Lake T, Pan W, Kastin AJ, Kirschner DA, Wood SG, Rockenstein E, Masliah E, Lorimer S, Tanzi RE, Larsen L. Snow AD, et al. Among authors: cam j. Sci Rep. 2019 Feb 6;9(1):561. doi: 10.1038/s41598-019-38645-0. Sci Rep. 2019. PMID: 30728442 Free PMC article.
12 results