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Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia.
Sartori R, Hagg A, Zampieri S, Armani A, Winbanks CE, Viana LR, Haidar M, Watt KI, Qian H, Pezzini C, Zanganeh P, Turner BJ, Larsson A, Zanchettin G, Pierobon ES, Moletta L, Valmasoni M, Ponzoni A, Attar S, Da Dalt G, Sperti C, Kustermann M, Thomson RE, Larsson L, Loveland KL, Costelli P, Megighian A, Merigliano S, Penna F, Gregorevic P, Sandri M. Sartori R, et al. Among authors: pezzini c. Sci Transl Med. 2021 Aug 4;13(605):eaay9592. doi: 10.1126/scitranslmed.aay9592. Sci Transl Med. 2021. PMID: 34349036
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia.
Wyart E, Hsu MY, Sartori R, Mina E, Rausch V, Pierobon ES, Mezzanotte M, Pezzini C, Bindels LB, Lauria A, Penna F, Hirsch E, Martini M, Mazzone M, Roetto A, Geninatti Crich S, Prenen H, Sandri M, Menga A, Porporato PE. Wyart E, et al. Among authors: pezzini c. EMBO Rep. 2022 Apr 5;23(4):e53746. doi: 10.15252/embr.202153746. Epub 2022 Feb 24. EMBO Rep. 2022. PMID: 35199910 Free PMC article.