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The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat.
Villarán RF, de Pablos RM, Argüelles S, Espinosa-Oliva AM, Tomás-Camardiel M, Herrera AJ, Cano J, Machado A. Villarán RF, et al. Among authors: cano j. Neurotoxicology. 2009 May;30(3):403-13. doi: 10.1016/j.neuro.2009.02.011. Epub 2009 Feb 25. Neurotoxicology. 2009. PMID: 19442825
Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system.
Hernández-Romero MC, Delgado-Cortés MJ, Sarmiento M, de Pablos RM, Espinosa-Oliva AM, Argüelles S, Bández MJ, Villarán RF, Mauriño R, Santiago M, Venero JL, Herrera AJ, Cano J, Machado A. Hernández-Romero MC, et al. Among authors: cano j. Neurotoxicology. 2012 Jun;33(3):347-60. doi: 10.1016/j.neuro.2012.01.018. Epub 2012 Feb 6. Neurotoxicology. 2012. PMID: 22330755
1,304 results