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Mutational tuning of galectin-3 specificity and biological function.
Salomonsson E, Carlsson MC, Osla V, Hendus-Altenburger R, Kahl-Knutson B, Oberg CT, Sundin A, Nilsson R, Nordberg-Karlsson E, Nilsson UJ, Karlsson A, Rini JM, Leffler H. Salomonsson E, et al. Among authors: carlsson mc. J Biol Chem. 2010 Nov 5;285(45):35079-91. doi: 10.1074/jbc.M109.098160. Epub 2010 Aug 31. J Biol Chem. 2010. PMID: 20807768 Free PMC article.
Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin-glycan specificities in a natural context.
Nielsen MI, Stegmayr J, Grant OC, Yang Z, Nilsson UJ, Boos I, Carlsson MC, Woods RJ, Unverzagt C, Leffler H, Wandall HH. Nielsen MI, et al. Among authors: carlsson mc. J Biol Chem. 2018 Dec 28;293(52):20249-20262. doi: 10.1074/jbc.RA118.004636. Epub 2018 Nov 1. J Biol Chem. 2018. PMID: 30385505 Free PMC article.
Extracellular and intracellular small-molecule galectin-3 inhibitors.
Stegmayr J, Zetterberg F, Carlsson MC, Huang X, Sharma G, Kahl-Knutson B, Schambye H, Nilsson UJ, Oredsson S, Leffler H. Stegmayr J, et al. Among authors: carlsson mc. Sci Rep. 2019 Feb 18;9(1):2186. doi: 10.1038/s41598-019-38497-8. Sci Rep. 2019. PMID: 30778105 Free PMC article.
Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.
Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H. Carlsson MC, et al. Biochim Biophys Acta. 2012 Sep;1820(9):1366-72. doi: 10.1016/j.bbagen.2012.01.007. Epub 2012 Jan 17. Biochim Biophys Acta. 2012. PMID: 22285770
17 results