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nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome.
Dagher M, Ongo G, Robichaud N, Kong J, Rho W, Teahulos I, Tavakoli A, Bovaird S, Merjaneh S, Tan A, Edwardson K, Scheepers C, Ng A, Hajjar A, Sow B, Vrouvides M, Lee A, DeCorwin-Martin P, Rasool S, Huang J, Han Y, Erps T, Coffin S, Chandrasekaran SN, Miller L, Kost-Alimova M, Skepner A, Singh S, Carpenter AE, Munzar J, Juncker D. Dagher M, et al. Among authors: carpenter ae. bioRxiv [Preprint]. 2023 Jun 28:2023.04.17.535914. doi: 10.1101/2023.04.17.535914. bioRxiv. 2023. PMID: 37131604 Free PMC article. Preprint.
Applications in image-based profiling of perturbations.
Caicedo JC, Singh S, Carpenter AE. Caicedo JC, et al. Among authors: carpenter ae. Curr Opin Biotechnol. 2016 Jun;39:134-142. doi: 10.1016/j.copbio.2016.04.003. Epub 2016 Apr 17. Curr Opin Biotechnol. 2016. PMID: 27089218 Free article. Review.
Image-based profiling for drug discovery: due for a machine-learning upgrade?
Chandrasekaran SN, Ceulemans H, Boyd JD, Carpenter AE. Chandrasekaran SN, et al. Among authors: carpenter ae. Nat Rev Drug Discov. 2021 Feb;20(2):145-159. doi: 10.1038/s41573-020-00117-w. Epub 2020 Dec 22. Nat Rev Drug Discov. 2021. PMID: 33353986 Free PMC article. Review.
Evaluating batch correction methods for image-based cell profiling.
Arevalo J, Su E, van Dijk R, Carpenter AE, Singh S. Arevalo J, et al. Among authors: carpenter ae. bioRxiv [Preprint]. 2024 Feb 28:2023.09.15.558001. doi: 10.1101/2023.09.15.558001. bioRxiv. 2024. PMID: 37745478 Free PMC article. Preprint.
Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations.
Chandrasekaran SN, Cimini BA, Goodale A, Miller L, Kost-Alimova M, Jamali N, Doench JG, Fritchman B, Skepner A, Melanson M, Kalinin AA, Arevalo J, Haghighi M, Caicedo JC, Kuhn D, Hernandez D, Berstler J, Shafqat-Abbasi H, Root DE, Swalley SE, Garg S, Singh S, Carpenter AE. Chandrasekaran SN, et al. Among authors: carpenter ae. Nat Methods. 2024 Apr 9. doi: 10.1038/s41592-024-02241-6. Online ahead of print. Nat Methods. 2024. PMID: 38594452
Increasing the Content of High-Content Screening: An Overview.
Singh S, Carpenter AE, Genovesio A. Singh S, et al. Among authors: carpenter ae. J Biomol Screen. 2014 Jun;19(5):640-50. doi: 10.1177/1087057114528537. Epub 2014 Apr 7. J Biomol Screen. 2014. PMID: 24710339 Free PMC article. Review.
194 results