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Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication.
Athreya AP, Neavin D, Carrillo-Roa T, Skime M, Biernacka J, Frye MA, Rush AJ, Wang L, Binder EB, Iyer RK, Weinshilboum RM, Bobo WV. Athreya AP, et al. Among authors: carrillo roa t. Clin Pharmacol Ther. 2019 Oct;106(4):855-865. doi: 10.1002/cpt.1482. Epub 2019 Jun 29. Clin Pharmacol Ther. 2019. PMID: 31012492 Free PMC article.
ERICH3: vesicular association and antidepressant treatment response.
Liu D, Zhuang Y, Zhang L, Gao H, Neavin D, Carrillo-Roa T, Wang Y, Yu J, Qin S, Kim DC, Liu E, Nguyen TTL, Biernacka JM, Kaddurah-Daouk R, Dunlop BW, Craighead WE, Mayberg HS, Binder EB, Frye MA, Wang L, Weinshilboum RM. Liu D, et al. Among authors: carrillo roa t. Mol Psychiatry. 2021 Jun;26(6):2415-2428. doi: 10.1038/s41380-020-00940-y. Epub 2020 Nov 23. Mol Psychiatry. 2021. PMID: 33230203 Free PMC article.
A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression.
Wei YB, McCarthy M, Ren H, Carrillo-Roa T, Shekhtman T, DeModena A, Liu JJ, Leckband SG, Mors O, Rietschel M, Henigsberg N, Cattaneo A, Binder EB, Aitchison KJ, Kelsoe JR. Wei YB, et al. Among authors: carrillo roa t. Mol Psychiatry. 2020 Jun;25(6):1312-1322. doi: 10.1038/s41380-019-0397-1. Epub 2019 Mar 15. Mol Psychiatry. 2020. PMID: 30874608 Free PMC article.
Identifying the Common Genetic Basis of Antidepressant Response.
Pain O, Hodgson K, Trubetskoy V, Ripke S, Marshe VS, Adams MJ, Byrne EM, Campos AI, Carrillo-Roa T, Cattaneo A, Als TD, Souery D, Dernovsek MZ, Fabbri C, Hayward C, Henigsberg N, Hauser J, Kennedy JL, Lenze EJ, Lewis G, Müller DJ, Martin NG, Mulsant BH, Mors O, Perroud N, Porteous DJ, Rentería ME, Reynolds CF 3rd, Rietschel M, Uher R, Wigmore EM, Maier W, Wray NR, Aitchison KJ, Arolt V, Baune BT, Biernacka JM, Bondolfi G, Domschke K, Kato M, Li QS, Liu YL, Serretti A, Tsai SJ, Turecki G, Weinshilboum R; GSRD Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; McIntosh AM, Lewis CM. Pain O, et al. Among authors: carrillo roa t. Biol Psychiatry Glob Open Sci. 2022 Apr;2(2):115-126. doi: 10.1016/j.bpsgos.2021.07.008. Biol Psychiatry Glob Open Sci. 2022. PMID: 35712048 Free PMC article.
Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity.
Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, Uhr M, Holsboer F, Sillaber I, Binder EB, Müller MB. Carrillo-Roa T, et al. PLoS Biol. 2017 Dec 28;15(12):e2002690. doi: 10.1371/journal.pbio.2002690. eCollection 2017 Dec. PLoS Biol. 2017. PMID: 29283992 Free PMC article.
"DNA Methylation signatures in panic disorder".
Iurato S, Carrillo-Roa T, Arloth J, Czamara D, Diener-Hölzl L, Lange J, Müller-Myhsok B, Binder EB, Erhardt A. Iurato S, et al. Transl Psychiatry. 2017 Dec 18;7(12):1287. doi: 10.1038/s41398-017-0026-1. Transl Psychiatry. 2017. PMID: 29249830 Free PMC article.
Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder.
Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS. Dunlop BW, et al. Biol Psychiatry. 2017 Dec 15;82(12):866-874. doi: 10.1016/j.biopsych.2017.06.024. Epub 2017 Jul 4. Biol Psychiatry. 2017. PMID: 28793974 Free PMC article. Clinical Trial.
DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.
Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB. Pape JC, et al. Among authors: carrillo roa t. Clin Epigenetics. 2018 Nov 3;10(1):136. doi: 10.1186/s13148-018-0569-x. Clin Epigenetics. 2018. PMID: 30390684 Free PMC article. Clinical Trial.
27 results