Supersulphides provide airway protection in viral and chronic lung diseases.
Matsunaga T, Sano H, Takita K, Morita M, Yamanaka S, Ichikawa T, Numakura T, Ida T, Jung M, Ogata S, Yoon S, Fujino N, Kyogoku Y, Sasaki Y, Koarai A, Tamada T, Toyama A, Nakabayashi T, Kageyama L, Kyuwa S, Inaba K, Watanabe S, Nagy P, Sawa T, Oshiumi H, Ichinose M, Yamada M, Sugiura H, Wei FY, Motohashi H, Akaike T.
Matsunaga T, et al.
Nat Commun. 2023 Jul 25;14(1):4476. doi: 10.1038/s41467-023-40182-4.
Nat Commun. 2023.
PMID: 37491435
Free PMC article.
Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA synthetase (CARS2) that functions as a principal cysteine persulphide synthase (CPERS). ...Lung damage and subsequent lethality that result from oxidative stress and inflammation in mouse models of COPD, IP …
Their synthesis is mainly mediated by mitochondrial cysteinyl-tRNA synthetase (CARS2) that functions as a principal cysteine persulph …