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IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. Núñez FJ, et al. Among authors: castro mg. Sci Transl Med. 2019 Feb 13;11(479):eaaq1427. doi: 10.1126/scitranslmed.aaq1427. Sci Transl Med. 2019. PMID: 30760578 Free PMC article.
Gene therapy for pituitary tumours.
Davis JR, Lowenstein PR, McNeilly AS, Castro MG. Davis JR, et al. Among authors: castro mg. Endocr Relat Cancer. 1999 Dec;6(4):475-81. doi: 10.1677/erc.0.0060475. Endocr Relat Cancer. 1999. PMID: 10730901 Review. No abstract available.
The basic science of brain-tumour gene therapy.
Lowenstein PR, Cowen R, Thomas C, Castro MG. Lowenstein PR, et al. Among authors: castro mg. Biochem Soc Trans. 1999 Dec;27(6):873-81. doi: 10.1042/bst0270873. Biochem Soc Trans. 1999. PMID: 10830120 Review. No abstract available.
445 results