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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 5
1998 6
1999 11
2000 13
2001 22
2002 31
2003 42
2004 41
2005 51
2006 70
2007 84
2008 85
2009 112
2010 121
2011 149
2012 151
2013 141
2014 168
2015 164
2016 167
2017 177
2018 161
2019 168
2020 212
2021 227
2022 229
2023 194
2024 87

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2,712 results

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Page 1
The CCL20-CCR6 Axis in Cancer Progression.
Kadomoto S, Izumi K, Mizokami A. Kadomoto S, et al. Int J Mol Sci. 2020 Jul 22;21(15):5186. doi: 10.3390/ijms21155186. Int J Mol Sci. 2020. PMID: 32707869 Free PMC article. Review.
The CCL20-CCR6 axis has long been known to be involved in inflammatory and infectious diseases, such as rheumatoid arthritis and human immunodeficiency virus infections. ...The present article reviewed the role of the CCL20-CCR6 axis in cancer progression and its po …
The CCL20-CCR6 axis has long been known to be involved in inflammatory and infectious diseases, such as rheumatoid arthritis and huma …
CCR6-CCL20 axis as a therapeutic target for autoimmune diseases.
Meitei HT, Jadhav N, Lal G. Meitei HT, et al. Autoimmun Rev. 2021 Jul;20(7):102846. doi: 10.1016/j.autrev.2021.102846. Epub 2021 May 7. Autoimmun Rev. 2021. PMID: 33971346 Review.
CCL20 is mainly produced by epithelial cells, and its expression is increased by several folds under inflammatory conditions. ...This review discussed the importance of the CCR6-CCL20 axis in IBD, PS, RA, and MS, and recent advances in targeting the CCR6-CCL20 …
CCL20 is mainly produced by epithelial cells, and its expression is increased by several folds under inflammatory conditions. ...This …
PMN-MDSCs modulated by CCL20 from cancer cells promoted breast cancer cell stemness through CXCL2-CXCR2 pathway.
Zhang R, Dong M, Tu J, Li F, Deng Q, Xu J, He X, Ding J, Xia J, Sheng D, Chang Z, Ma W, Dong H, Zhang Y, Zhang L, Zhang L, Liu S. Zhang R, et al. Signal Transduct Target Ther. 2023 Mar 1;8(1):97. doi: 10.1038/s41392-023-01337-3. Signal Transduct Target Ther. 2023. PMID: 36859354 Free PMC article.
However, it is unclear whether CCL20 affects breast cancer progression by remodeling the tumor microenvironment (TME). ...PMN-MDSCs from CCL20-overexpressing cell orthotopic allograft tumors (CCL20-modulated PMN-MDSCs) secreted amounts of C-X-C motif chemokin …
However, it is unclear whether CCL20 affects breast cancer progression by remodeling the tumor microenvironment (TME). ...PMN-MDSCs f …
Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization.
Xu C, Fan L, Lin Y, Shen W, Qi Y, Zhang Y, Chen Z, Wang L, Long Y, Hou T, Si J, Chen S. Xu C, et al. Gut Microbes. 2021 Jan-Dec;13(1):1980347. doi: 10.1080/19490976.2021.1980347. Gut Microbes. 2021. PMID: 34632963 Free PMC article.
F. nucleatum promoted macrophage infiltration through CCL20 activation and simultaneously induced M2 macrophage polarization, enhancing the metastasis of CRC. ...In conclusion, F. nucleatum promotes CRC metastasis through the miR-1322/CCL20 axis and M2 polarization. …
F. nucleatum promoted macrophage infiltration through CCL20 activation and simultaneously induced M2 macrophage polarization, enhanci …
CCL20 Signaling in the Tumor Microenvironment.
Chen W, Qin Y, Liu S. Chen W, et al. Adv Exp Med Biol. 2020;1231:53-65. doi: 10.1007/978-3-030-36667-4_6. Adv Exp Med Biol. 2020. PMID: 32060846 Review.
CCL20, as a chemokine, plays an important role in rheumatoid arthritis, psoriasis, and other diseases by binding to its receptor CCR6. ...This article reviews and discusses the previous studies on CCL20 roles in cancers from the aspects of its specific effects on va …
CCL20, as a chemokine, plays an important role in rheumatoid arthritis, psoriasis, and other diseases by binding to its receptor CCR6 …
Plasma Olink Proteomics Identifies CCL20 as a Novel Predictive and Diagnostic Inflammatory Marker for Preeclampsia.
Wang X, Yip KC, He A, Tang J, Liu S, Yan R, Zhang Q, Li R. Wang X, et al. J Proteome Res. 2022 Dec 2;21(12):2998-3006. doi: 10.1021/acs.jproteome.2c00544. Epub 2022 Oct 27. J Proteome Res. 2022. PMID: 36301636 Free PMC article.
Among them, fibroblast growth factor 21 (FGF-21) and cysteine-cysteine motif chemokine ligand 20 (CCL20) had the largest fold changes. We further validated the levels of CCL20 in the late (43 with PE and 44 controls) and early (37 with PE and 37 controls) pregnancy …
Among them, fibroblast growth factor 21 (FGF-21) and cysteine-cysteine motif chemokine ligand 20 (CCL20) had the largest fold changes …
SMAD4 Suppresses Colitis-associated Carcinoma Through Inhibition of CCL20/CCR6-mediated Inflammation.
Hanna DN, Smith PM, Novitskiy SV, Washington MK, Zi J, Weaver CJ, Hamaamen JA, Lewis KB, Zhu J, Yang J, Liu Q, Beauchamp RD, Means AL. Hanna DN, et al. Gastroenterology. 2022 Nov;163(5):1334-1350.e14. doi: 10.1053/j.gastro.2022.07.016. Epub 2022 Jul 19. Gastroenterology. 2022. PMID: 35863523 Free PMC article.
Here, we examine the role of the chemokine/receptor pair CCL20/c-c motif chemokine receptor 6 (CCR6) in mediating colitis-associated colon carcinogenesis induced by SMAD4 loss. ...A key downstream node in this regulation is suppression of epithelial CCL20 signaling …
Here, we examine the role of the chemokine/receptor pair CCL20/c-c motif chemokine receptor 6 (CCR6) in mediating colitis-associated …
The CCL20 and CCR6 axis in psoriasis.
Furue K, Ito T, Tsuji G, Nakahara T, Furue M. Furue K, et al. Scand J Immunol. 2020 Mar;91(3):e12846. doi: 10.1111/sji.12846. Epub 2019 Nov 24. Scand J Immunol. 2020. PMID: 31692008 Free article. Review.
Thus, the CCL20/CCR6 axis works as a driving force that prepares an IL-17A-rich cutaneous milieu. In this review, we summarize the current research topics on the CCL20/CCR6 axis and the therapeutic intervention of this axis for psoriasis....
Thus, the CCL20/CCR6 axis works as a driving force that prepares an IL-17A-rich cutaneous milieu. In this review, we summarize the cu …
Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-kappaB signaling.
Wang D, Yang L, Yu W, Wu Q, Lian J, Li F, Liu S, Li A, He Z, Liu J, Sun Z, Yuan W, Zhang Y. Wang D, et al. J Immunother Cancer. 2019 Aug 8;7(1):215. doi: 10.1186/s40425-019-0701-2. J Immunother Cancer. 2019. PMID: 31395078 Free PMC article.
The high level of CCL20 was closely associated with chemoresistance and poor survival in CRC patients. Among the drugs in Folfox chemotherapy, we confirmed that 5-FU increased the expression of CCL20 in CRC. Moreover, CCL20 derived from 5-FU-resistant CRC cel …
The high level of CCL20 was closely associated with chemoresistance and poor survival in CRC patients. Among the drugs in Folfox chem …
Salivary CCL20 Level as a Biomarker for Oral Squamous Cell Carcinoma.
Ueda S, Goto M, Hashimoto K, Hasegawa S, Imazawa M, Takahashi M, Oh-Iwa I, Shimozato K, Nagao T, Nomoto S. Ueda S, et al. Cancer Genomics Proteomics. 2021 Mar-Apr;18(2):103-112. doi: 10.21873/cgp.20245. Cancer Genomics Proteomics. 2021. PMID: 33608307 Free PMC article. Review.
Fusobacterium was identified as the predominant bacteria in OSCC and correlated with CCL20 expression level. OSCC screening based on salivary CCL20 expression enabled successful differentiation between patients with OSCC and HVs. CONCLUSION: CCL20 expression …
Fusobacterium was identified as the predominant bacteria in OSCC and correlated with CCL20 expression level. OSCC screening based on …
2,712 results