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Year Number of Results
1983 1
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2002 13
2003 10
2004 17
2005 8
2006 15
2007 20
2008 27
2009 22
2010 21
2011 27
2012 27
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509 results

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Page 1
The Roles of CCR9/CCL25 in Inflammation and Inflammation-Associated Diseases.
Wu X, Sun M, Yang Z, Lu C, Wang Q, Wang H, Deng C, Liu Y, Yang Y. Wu X, et al. Front Cell Dev Biol. 2021 Aug 19;9:686548. doi: 10.3389/fcell.2021.686548. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34490243 Free PMC article. Review.
C-C chemokine receptor 9 (CCR9) and its ligand C-C chemokine ligand 25 (CCL25) are involved in the regulating the occurrence and development of various diseases, which has become a research hotspot. ...Therefore, the purpose of this review gives an overview of the recent a …
C-C chemokine receptor 9 (CCR9) and its ligand C-C chemokine ligand 25 (CCL25) are involved in the regulating the occurrence and deve …
CCR9 and CCL25: A review of their roles in tumor promotion.
Xu B, Deng C, Wu X, Ji T, Zhao L, Han Y, Yang W, Qi Y, Wang Z, Yang Z, Yang Y. Xu B, et al. J Cell Physiol. 2020 Dec;235(12):9121-9132. doi: 10.1002/jcp.29782. Epub 2020 May 13. J Cell Physiol. 2020. PMID: 32401349 Review.
This review evaluates recent advances in understanding the role of CCR9/CCL25 in cancer development. First, we outline the general background of chemokines in cancer and the structure and function of CCR9 and CCL25. Next, we describe the basic function of CCR9/CC …
This review evaluates recent advances in understanding the role of CCR9/CCL25 in cancer development. First, we outline the general ba …
CCL25 Signaling in the Tumor Microenvironment.
Mir H, Singh S. Mir H, et al. Adv Exp Med Biol. 2021;1302:99-111. doi: 10.1007/978-3-030-62658-7_8. Adv Exp Med Biol. 2021. PMID: 34286444
Association of increased CCR9 and CCL25 levels in various tumors has demonstrated the significance of this axis as a tool commonly used by cancer to flourish. ...Lastly, this chapter abridges the latest research efforts and challenges in using the CCR9-CCL25 axis as …
Association of increased CCR9 and CCL25 levels in various tumors has demonstrated the significance of this axis as a tool commonly us …
CCL25 Inhibition Alleviates Sepsis-Induced Acute Lung Injury and Inflammation.
Xia D, Wang S, Liu A, Li L, Zhou P, Xu S. Xia D, et al. Infect Drug Resist. 2022 Jun 25;15:3309-3321. doi: 10.2147/IDR.S352544. eCollection 2022. Infect Drug Resist. 2022. PMID: 35782530 Free PMC article.
However, the role and mechanism of CCL25 in ALI are not fully understood yet. The aim of this study was to explore the relationship between acute lung injury and CCL25. ...Results from luciferase assays and chromatin immunoprecipitation assays showed that inhibition …
However, the role and mechanism of CCL25 in ALI are not fully understood yet. The aim of this study was to explore the relationship b …
CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4.
Korbecki J, Kojder K, Simińska D, Bohatyrewicz R, Gutowska I, Chlubek D, Baranowska-Bosiacka I. Korbecki J, et al. Int J Mol Sci. 2020 Nov 9;21(21):8412. doi: 10.3390/ijms21218412. Int J Mol Sci. 2020. PMID: 33182504 Free PMC article. Review.
The first part of this review discusses the importance of CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CCL28 in cancer. Here, we discuss the significance of CCL2 (MCP-1), CCL7, CCL8, CCL11, CCL13, CCL14, CCL15, CCL16, CCL17, CCL22, CCL23, CCL24, an …
The first part of this review discusses the importance of CCL1, CCL3, CCL4, CCL5, CCL18, CCL19, CCL20, CCL21, CCL25, CCL27, and CCL28 …
CCL25 and CCR9 is a unique pathway that potentiates pannus formation by remodeling RA macrophages into mature osteoclasts.
Umar S, Palasiewicz K, Van Raemdonck K, Volin MV, Romay B, Ahmad I, Tetali C, Sweiss N, Amin MA, Zomorrodi RK, Shahrara S. Umar S, et al. Eur J Immunol. 2021 Apr;51(4):903-914. doi: 10.1002/eji.202048681. Epub 2021 Jan 25. Eur J Immunol. 2021. PMID: 33347617 Free PMC article.
This study elucidates the mechanism of CCL25 and CCR9 in rheumatoid arthritis (RA). RA synovial fluid (SF) expresses elevated levels of CCL25 compared to OA SF and plasma from RA and normal. ...Activation of p38 and ERK cascades are also responsible for the CCL25 …
This study elucidates the mechanism of CCL25 and CCR9 in rheumatoid arthritis (RA). RA synovial fluid (SF) expresses elevated levels …
CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway.
Chai S, Wen Z, Zhang R, Bai Y, Liu J, Li J, Kongling W, Chen W, Wang F, Gao L. Chai S, et al. PeerJ. 2022 Aug 19;10:e13844. doi: 10.7717/peerj.13844. eCollection 2022. PeerJ. 2022. PMID: 36003306 Free PMC article.
Western blot and RT-qPCR assays were carried out to measure the downstream factors of the interaction of CCL25 and CCR9. The effect of CCL25 on the development of SACC in vivo was examined by a xenograft tumor model in nude mice following CCL25, Vercirnon and …
Western blot and RT-qPCR assays were carried out to measure the downstream factors of the interaction of CCL25 and CCR9. The effect o …
CCR9-CCL25 mediated plasmacytoid dendritic cell homing and contributed the immunosuppressive microenvironment in gastric cancer.
Yu H, Mei Y, Dong Y, Chen C, Lin X, Jin H, Yu J, Liu X. Yu H, et al. Transl Oncol. 2023 Jul;33:101682. doi: 10.1016/j.tranon.2023.101682. Epub 2023 Apr 29. Transl Oncol. 2023. PMID: 37126939 Free PMC article.
Evidences has been shown that chemokine receptor 9 (CCR9) is an important molecule that attracts pDCs homing to the digestive tract and the latter are involved in the formation of digestive tract immune tolerance. The aim of this study was to explore the role of CCR9-CCL25 …
Evidences has been shown that chemokine receptor 9 (CCR9) is an important molecule that attracts pDCs homing to the digestive tract and the …
Therapies with CCL25 require controlled release via microparticles to avoid strong inflammatory reactions.
Spinnen J, Fröhlich K, Sinner N, Stolk M, Ringe J, Shopperly L, Sittinger M, Dehne T, Seifert M. Spinnen J, et al. J Nanobiotechnology. 2021 Mar 25;19(1):83. doi: 10.1186/s12951-021-00830-7. J Nanobiotechnology. 2021. PMID: 33766057 Free PMC article.
The aim of this study was to evaluate the reaction of different immune cell subsets upon stimulation with different dosages of CCL25 in comparison to CCL25 released from PLGA particles. RESULTS: Immune cell subsets were treated for up to 5 days with CCL25 and …
The aim of this study was to evaluate the reaction of different immune cell subsets upon stimulation with different dosages of CCL25 …
CCL25-Supplemented Hyaluronic Acid Attenuates Cartilage Degeneration in a Guinea Pig Model of Knee Osteoarthritis.
Ringe J, Hemmati-Sadeghi S, Fröhlich K, Engels A, Reiter K, Dehne T, Sittinger M. Ringe J, et al. J Orthop Res. 2019 Aug;37(8):1723-1729. doi: 10.1002/jor.24312. Epub 2019 Apr 29. J Orthop Res. 2019. PMID: 30977553 Free article.
The measured average physiological concentration of CCL25 in SF of animals is 85 39 pg/ml. MSC showed a 3.2-fold increase in cell migration at 1,000 nM CCL25 in vitro demonstrating the biological migratory activity of CCL25 on these cells. ...Similarly, OA sc …
The measured average physiological concentration of CCL25 in SF of animals is 85 39 pg/ml. MSC showed a 3.2-fold increase in cell mig …
509 results