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CDC37L1 acts as a suppressor of migration and proliferation in gastric cancer by down-regulating CDK6.
Li L, Tao X, Li Y, Gao Y, Li Q. Li L, et al. J Cancer. 2021 Mar 31;12(11):3145-3153. doi: 10.7150/jca.56097. eCollection 2021. J Cancer. 2021. PMID: 33976724 Free PMC article.
Consistently, data from online database analysis demonstrated that CDC37L1 level was decreased in stage 4 patients and low expression of CDC37L1 indicated a poor prognosis. ...In the meantime, CDC37L1 also inhibited the tumorigenicity of GC cells in nude mice …
Consistently, data from online database analysis demonstrated that CDC37L1 level was decreased in stage 4 patients and low expression …
Hsp90-interacting Co-chaperones and their Family Proteins in Tau Regulation: Introducing a Novel Role for Cdc37L1.
Peak SL, Gracia L, Lora G, Jinwal UK. Peak SL, et al. Neuroscience. 2021 Jan 15;453:312-323. doi: 10.1016/j.neuroscience.2020.11.020. Epub 2020 Nov 24. Neuroscience. 2021. PMID: 33246057 Review.
Here, we provide a holistic review of these selected co-chaperones and their family proteins and introduce a novel Hsp90-binding Cdc37 relative, Cdc37-like-1 (Cdc37L1 or L1) in tau regulation. Overall, the proteins discussed here highlight the importance of studying family …
Here, we provide a holistic review of these selected co-chaperones and their family proteins and introduce a novel Hsp90-binding Cdc37 relat …
miR-15a and miR-20b sensitize hepatocellular carcinoma cells to sorafenib through repressing CDC37L1 and consequent PPIA downregulation.
Li L, Yu S, Chen J, Quan M, Gao Y, Li Y. Li L, et al. Cell Death Discov. 2022 Jun 27;8(1):297. doi: 10.1038/s41420-022-01094-2. Cell Death Discov. 2022. PMID: 35760798 Free PMC article.
Mechanistically, CDC37L1, as a cochaperone, effectively increased the expression of peptidylprolyl isomerase A (PPIA) through strengthening the binding between heat shock protein 90 (HSP90) and PPIA. The results from immunohistochemical staining of a HCC tissue microarray …
Mechanistically, CDC37L1, as a cochaperone, effectively increased the expression of peptidylprolyl isomerase A (PPIA) through strengt …
A novel immunodiagnosis panel for hepatocellular carcinoma based on bioinformatics and the autoantibody-antigen system.
Wu J, Wang P, Han Z, Li T, Yi C, Qiu C, Yang Q, Sun G, Dai L, Shi J, Wang K, Ye H. Wu J, et al. Cancer Sci. 2022 Feb;113(2):411-422. doi: 10.1111/cas.15217. Epub 2021 Dec 14. Cancer Sci. 2022. PMID: 34821436 Free PMC article.
The test set further verified the model. Eleven TAAs were selected (AAGAB, C17orf75, CDC37L1, DUSP6, EID3, PDIA2, RGS20, PCNA, TAF7L, TBC1D13, and ZIC2). The titer of six autoantibodies (PCNA, AAGAB, CDC37L1, TAF7L, DUSP6, and ZIC2) had a significant difference in a …
The test set further verified the model. Eleven TAAs were selected (AAGAB, C17orf75, CDC37L1, DUSP6, EID3, PDIA2, RGS20, PCNA, TAF7L, …
Protein profiling of testicular tissue from boars with different levels of hyperactive sperm motility.
van Son M, Våge DI, Skaugen M, Tremoen NH, Gaustad AH, Zeremichael TT, Myromslien FD, Grindflek E. van Son M, et al. Acta Vet Scand. 2022 Sep 5;64(1):21. doi: 10.1186/s13028-022-00642-1. Acta Vet Scand. 2022. PMID: 36064611 Free PMC article.
The most significant differentially expressed proteins were mediator complex subunit 28 (MED28), cell division cycle 37 like 1 (CDC37L1), ubiquitin specific peptidase 10 (USP10), zinc finger FYVE-type containing 26 (ZFYVE26), protein kinase C delta (PRKCD), actinin alpha 4 …
The most significant differentially expressed proteins were mediator complex subunit 28 (MED28), cell division cycle 37 like 1 (CDC37L1 …
Combination of an Autoantibody Panel and Alpha-Fetoprotein for Early Detection of Hepatitis B Virus-Associated Hepatocellular Carcinoma.
Shen Y, Chen J, Wu J, Li T, Yi C, Wang K, Wang P, Sun C, Ye H. Shen Y, et al. Cancer Prev Res (Phila). 2024 May 2;17(5):227-235. doi: 10.1158/1940-6207.CAPR-23-0311. Cancer Prev Res (Phila). 2024. PMID: 38489403
A total of four candidate tumor-associated autoantibodies (TAAb; anti-ZIC2, anti-PCNA, anti-CDC37L1, and anti-DUSP6) were identified by human proteome microarray (52 samples) and bioinformatics analysis. ...Finally, a diagnostic panel with three TAAbs (anti-ZIC2, anti-C …
A total of four candidate tumor-associated autoantibodies (TAAb; anti-ZIC2, anti-PCNA, anti-CDC37L1, and anti-DUSP6) were identified …
Identification of candidate molecular markers of nasopharyngeal carcinoma by microarray analysis of subtracted cDNA libraries constructed by suppression subtractive hybridization.
Zhou Y, Zeng Z, Zhang W, Xiong W, Li X, Zhang B, Yi W, Xiao L, Wu M, Shen S, Li X, Cao L, Tang K, Li G. Zhou Y, et al. Eur J Cancer Prev. 2008 Nov;17(6):561-71. doi: 10.1097/CEJ.0b013e328305a0e8. Eur J Cancer Prev. 2008. PMID: 18941378
Palate, lung, and nasal epithelium carcinoma (PLUNC)-associated and homo sapien cell division cycle 37 homolog (Saccharomyces cerevisiae)-like 1 (CDC37L1) genes had a higher frequency than others in the 68 poorly expressed colonies in NPC. ...The data suggested that PLUNC …
Palate, lung, and nasal epithelium carcinoma (PLUNC)-associated and homo sapien cell division cycle 37 homolog (Saccharomyces cerevisiae)-li …
Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy.
Huang H, Luo B, Wang B, Wu Q, Liang Y, He Y. Huang H, et al. Med Sci Monit. 2018 Oct 28;24:7697-7709. doi: 10.12659/MSM.912984. Med Sci Monit. 2018. PMID: 30368515 Free PMC article.
The FOS, TIMP1, and SERPINE1 hub genes, as well as some key TFs, demonstrated important roles in the progression of HF caused by iDCM. CEBPD, CEBOB, CDC37L1, and SRGN may be new targets for HF in iDCM patients. CONCLUSIONS The identified DEGs and their enriched pathways pr …
The FOS, TIMP1, and SERPINE1 hub genes, as well as some key TFs, demonstrated important roles in the progression of HF caused by iDCM. CEBPD …
Prognostic genes of hepatocellular carcinoma based on gene coexpression network analysis.
Xu B, Lv W, Li X, Zhang L, Lin J. Xu B, et al. J Cell Biochem. 2019 Jul;120(7):11616-11623. doi: 10.1002/jcb.28441. Epub 2019 Feb 18. J Cell Biochem. 2019. PMID: 30775801
These hub genes were subsequently validated by a new data set GSE76427 and KM Plotter Online Tool, and the results indicated that 10 genes (FBXO43, ARHGEF39, MXD3, VIPR1, DNASE1L3, PHLDA1, CSRNP1, ADR2B, C1RL, and CDC37L1) could act as prognosis and progression biomarkers …
These hub genes were subsequently validated by a new data set GSE76427 and KM Plotter Online Tool, and the results indicated that 10 genes ( …
Comprehensive analysis of potential prognostic genes for the construction of a competing endogenous RNA regulatory network in hepatocellular carcinoma.
Yue C, Ren Y, Ge H, Liang C, Xu Y, Li G, Wu J. Yue C, et al. Onco Targets Ther. 2019 Jan 14;12:561-576. doi: 10.2147/OTT.S188913. eCollection 2019. Onco Targets Ther. 2019. PMID: 30679912 Free PMC article.
There were 13 key potential prognostic genes in the ceRNA regulatory network: eleven upregulated genes (CCNB1, CEP55, CHEK1, EZH2, KPNA2, LRRC1, PBK, RRM2, SLC7A11, SUCO, and ZWINT) and two downregulated genes (ACSL1 and CDC37L1) whose expression might be regulated by eigh …
There were 13 key potential prognostic genes in the ceRNA regulatory network: eleven upregulated genes (CCNB1, CEP55, CHEK1, EZH2, KPNA2, LR …
14 results