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1999 1
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2015 5
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Page 1
Cigarette smoking, by accelerating the cell cycle, promotes the progression of non-small cell lung cancer through an HIF-1alpha-METTL3-m(6)A/CDK2AP2 axis.
Yang Y, Cheng C, He B, Du X, Liu J, Xia H, Wang P, Wu M, Wu H, Liu Q. Yang Y, et al. J Hazard Mater. 2023 Aug 5;455:131556. doi: 10.1016/j.jhazmat.2023.131556. Epub 2023 May 2. J Hazard Mater. 2023. PMID: 37156046
Down-regulation HIF-1alpha or METTL3 reversed these effects. meRIP-seq and RNA-seq revealed the m(6)A modification in Cyclin Dependent Kinase 2 Associated Protein 2 (CDK2AP2) mRNA as the key downstream target. Further, for NSCLC cells exposed to CSE, HIF-1alpha activated M …
Down-regulation HIF-1alpha or METTL3 reversed these effects. meRIP-seq and RNA-seq revealed the m(6)A modification in Cyclin Dependent Kinas …
Cdk2ap2 is a novel regulator for self-renewal of murine embryonic stem cells.
Deshpande AM, Khalid O, Kim JJ, Kim Y, Lindgren A, Clark AT, Wong DT. Deshpande AM, et al. Stem Cells Dev. 2012 Nov 1;21(16):3010-8. doi: 10.1089/scd.2012.0007. Epub 2012 Jun 25. Stem Cells Dev. 2012. PMID: 22548356 Free PMC article.
To understand the function of Cdk2ap2 during early development, we generated mESCs with homozygous disruption of the endogenous Cdk2ap2 locus (Cdk2ap2(tr/tr)). ...Furthermore, Cdk2ap2(tr/tr) mESCs were unable to form teratomas in severe combined immuno …
To understand the function of Cdk2ap2 during early development, we generated mESCs with homozygous disruption of the endogenous Cd …
Whole-genome resequencing reveals genetic diversity, differentiation, and selection signatures of yak breeds/populations in Qinghai, China.
Li G, Luo J, Wang F, Xu D, Ahmed Z, Chen S, Li R, Ma Z. Li G, et al. Front Genet. 2023 Jan 10;13:1034094. doi: 10.3389/fgene.2022.1034094. eCollection 2022. Front Genet. 2023. PMID: 36704337 Free PMC article.
Positive selection signals were detected in candidate genes associated with disease resistance (CDK2AP2, PLEC, and CYB5B), heat stress (NFAT5, HSF1, and SLC25A48), pigmentation (MCAM, RNF26, and BOP1), vision (C1QTNF5, MFRP, and TAX1BP3), milk quality (OPLAH and GRINA), ne …
Positive selection signals were detected in candidate genes associated with disease resistance (CDK2AP2, PLEC, and CYB5B), heat stres …
mRNA Expression of CDK2AP1 in Human Breast Cancer: Correlation with Clinical and Pathological Parameters.
Gera R, Mokbel L, Jiang WG, Mokbel K. Gera R, et al. Cancer Genomics Proteomics. 2018 Nov-Dec;15(6):447-452. doi: 10.21873/cgp.20103. Cancer Genomics Proteomics. 2018. PMID: 30343278 Free PMC article.
BACKGROUND: Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) interacts with CDK2AP2, modulates the actions of transforming growth factor-B1, cyclin-dependent kinase 2 and retinoblastoma protein, and closely interacts with micro-RNA21 and micro-RNA25. ...
BACKGROUND: Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) interacts with CDK2AP2, modulates the actions of transforming gr …
Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.
Spruijt CG, Gräwe C, Kleinendorst SC, Baltissen MPA, Vermeulen M. Spruijt CG, et al. FEBS J. 2021 May;288(10):3231-3245. doi: 10.1111/febs.15650. Epub 2020 Dec 14. FEBS J. 2021. PMID: 33283408 Free PMC article.
Furthermore, our experiments reveal that not only CDK2AP1 but also CDK2AP2 interacts with the NuRD complex. This interaction requires the C terminus of CHD proteins. ...
Furthermore, our experiments reveal that not only CDK2AP1 but also CDK2AP2 interacts with the NuRD complex. This interaction requires …
Dye-free gene expression detection by sequence-tagged reverse-transcription polymerase chain reaction coupled with pyrosequencing.
Zhang X, Wu H, Chen Z, Zhou G, Kajiyama T, Kambara H. Zhang X, et al. Anal Chem. 2009 Jan 1;81(1):273-81. doi: 10.1021/ac801964a. Anal Chem. 2009. PMID: 19049364
As the signal is detected by observing bioluminescence, neither dye, nor electrophoresis, or laser source was used. The expression levels of six kinds of genes (Cdk2ap2, Vps4b, Fas, Fos, Cdk4, and Actb) among the kidney, the brain, and the heart tissues of a mouse were acc …
As the signal is detected by observing bioluminescence, neither dye, nor electrophoresis, or laser source was used. The expression levels of …
SOX2OT knockdown derived changes in mitotic regulatory gene network of cancer cells.
Saghaeian Jazi M, Samaei NM, Mowla SJ, Arefnezhad B, Kouhsar M. Saghaeian Jazi M, et al. Cancer Cell Int. 2018 Sep 5;18:129. doi: 10.1186/s12935-018-0618-8. eCollection 2018. Cancer Cell Int. 2018. PMID: 30202240 Free PMC article.
Particularly, the cell cycle and mitotic regulatory genes expression including: CDK2, CDK2AP2, ACTR3, and chromosome structure associated genes like SMC4, INCENP and GNL3L are changed in treated cancer cells. ...
Particularly, the cell cycle and mitotic regulatory genes expression including: CDK2, CDK2AP2, ACTR3, and chromosome structure associ …
40 results