Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1983 1
1985 1
1986 1
1987 7
1988 4
1989 6
1990 7
1991 21
1992 12
1993 22
1994 32
1995 36
1996 34
1997 43
1998 44
1999 41
2000 35
2001 33
2002 37
2003 36
2004 51
2005 47
2006 40
2007 35
2008 39
2009 34
2010 31
2011 35
2012 31
2013 38
2014 36
2015 49
2016 41
2017 34
2018 56
2019 61
2020 63
2021 62
2022 54
2023 54
2024 12

Text availability

Article attribute

Article type

Publication date

Search Results

1,245 results

Results by year

Filters applied: . Clear all
Page 1
CDR1 Composition Can Affect Nanobody Recombinant Expression Yields.
Orlando M, Fortuna S, Oloketuyi S, Bajc G, Goldenzweig A, de Marco A. Orlando M, et al. Biomolecules. 2021 Sep 14;11(9):1362. doi: 10.3390/biom11091362. Biomolecules. 2021. PMID: 34572576 Free PMC article.
In principle, CDRs are not mutated because they are likely to be part of the antibody paratope, but in this work, we describe a mutagenesis strategy that specifically addresses CDR1. Its sequence was identified as an instability hot spot by the PROSS program, and the avail …
In principle, CDRs are not mutated because they are likely to be part of the antibody paratope, but in this work, we describe a mutagenesis …
The ABCs of Candida albicans Multidrug Transporter Cdr1.
Prasad R, Banerjee A, Khandelwal NK, Dhamgaye S. Prasad R, et al. Eukaryot Cell. 2015 Dec;14(12):1154-64. doi: 10.1128/EC.00137-15. Epub 2015 Sep 25. Eukaryot Cell. 2015. PMID: 26407965 Free PMC article. Review.
The ABC transporter Candida drug resistance 1 protein (Cdr1p) is a major player among these transporters that enables the pathogen to outplay the battery of antifungals encountered by it. The promiscuous Cdr1 protein fulfills the quintessential need of a model to study mol …
The ABC transporter Candida drug resistance 1 protein (Cdr1p) is a major player among these transporters that enables the pathogen to outpla …
A mechanism for how Cdr1/Nim1 kinase promotes mitotic entry by inhibiting Wee1.
Opalko HE, Nasa I, Kettenbach AN, Moseley JB. Opalko HE, et al. Mol Biol Cell. 2019 Dec 1;30(25):3015-3023. doi: 10.1091/mbc.E19-08-0430. Epub 2019 Oct 23. Mol Biol Cell. 2019. PMID: 31644361 Free PMC article.
Here, we show that both Cdr1 and Cdr2 promote Wee1 phosphorylation in cells, but only Cdr1 inhibits Wee1 kinase activity. ...This region is highly divergent among different Wee1 proteins, consistent with distinct regulatory mechanisms. A wee(4A) mutant that impairs …
Here, we show that both Cdr1 and Cdr2 promote Wee1 phosphorylation in cells, but only Cdr1 inhibits Wee1 kinase activity. ...T …
Participation of the ABC Transporter CDR1 in Azole Resistance of Candida lusitaniae.
Borgeat V, Brandalise D, Grenouillet F, Sanglard D. Borgeat V, et al. J Fungi (Basel). 2021 Sep 15;7(9):760. doi: 10.3390/jof7090760. J Fungi (Basel). 2021. PMID: 34575798 Free PMC article.
CDR1 expression in isolates with GOF MRR1 mutations was higher compared to wild types, which suggests that CDR1 is an additional (direct or indirect) target of MRR1. ...With R6G efflux readout as Cdr1 efflux capacity, our data showed that R6G efflux was incre …
CDR1 expression in isolates with GOF MRR1 mutations was higher compared to wild types, which suggests that CDR1 is an addition …
Nonidentical function of Upc2A binding sites in the Candida glabrata CDR1 promoter.
Vu BG, Moye-Rowley WS. Vu BG, et al. Genetics. 2022 Sep 30;222(2):iyac135. doi: 10.1093/genetics/iyac135. Genetics. 2022. PMID: 36063046 Free PMC article.
While this earlier work implicated Upc2A as an activator of CDR1 transcription, our further analyses revealed the presence of a second Upc2A binding site that negatively regulated CDR1 expression. ...A mutant version of SRE2 prevented in vitro DNA-binding by recombi …
While this earlier work implicated Upc2A as an activator of CDR1 transcription, our further analyses revealed the presence of a secon …
Circular RNA CDR1-AS contributes to pemetrexed and cisplatin chemoresistance through EGFR/PI3K signaling pathway in lung adenocarcinoma.
Mao Y, Xu R. Mao Y, et al. Biomed Pharmacother. 2020 Mar;123:109771. doi: 10.1016/j.biopha.2019.109771. Epub 2019 Dec 24. Biomed Pharmacother. 2020. PMID: 31881486 Free article.
CDR1-AS was an independent prognostic biomarker for LUAD patients. ...Silence of CDR1-AS re-sensitized A549/CR cells to PTX and CDDP. CDR1-AS was closely related with EGFR/PI3K signaling pathway in A549/CR cells. ...
CDR1-AS was an independent prognostic biomarker for LUAD patients. ...Silence of CDR1-AS re-sensitized A549/CR cells to PTX an …
Conserved motifs in T-cell receptor CDR1 and CDR2: implications for ligand and CD8 co-receptor binding.
Arden B. Arden B. Curr Opin Immunol. 1998 Feb;10(1):74-81. doi: 10.1016/s0952-7915(98)80035-6. Curr Opin Immunol. 1998. PMID: 9523115 Review.
Recent X-ray crystallographic structures of the T-cell receptor (TCR) alpha and beta chains, as well as their trimolecular complexes with peptide-MHC ligand, have established their structural similarity with the immunoglobulin molecules. The complementarity-determining region ( …
Recent X-ray crystallographic structures of the T-cell receptor (TCR) alpha and beta chains, as well as their trimolecular complexes with pe …
Expression of the onconeural protein CDR1 in cerebellum and ovarian cancer.
Totland C, Kråkenes T, Mazengia K, Haugen M, Vedeler C. Totland C, et al. Oncotarget. 2018 May 8;9(35):23975-23986. doi: 10.18632/oncotarget.25252. eCollection 2018 May 8. Oncotarget. 2018. PMID: 29844866 Free PMC article.
In cells overexpressing CDR1, CDR1 localized close to the plasma membrane in a polarized pattern at one edge. ...Therefore, CDR1 is probably not a marker for PCD. However, CDR1 may be associated with cell migration and differentiation....
In cells overexpressing CDR1, CDR1 localized close to the plasma membrane in a polarized pattern at one edge. ...Therefore, …
1,245 results