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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 4
2001 2
2002 2
2003 2
2004 1
2005 6
2006 4
2007 3
2008 4
2009 6
2010 11
2011 7
2012 10
2013 3
2014 7
2015 9
2016 4
2017 9
2018 8
2019 7
2020 12
2021 8
2022 15
2023 21
2024 2

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151 results

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Page 1
Celsr2-mediated morphological polarization and functional phenotype of reactive astrocytes in neural repair.
Liu A, Yu L, Li X, Zhang K, Zhang W, So KF, Tissir F, Qu Y, Zhou L. Liu A, et al. Glia. 2023 Aug;71(8):1985-2004. doi: 10.1002/glia.24378. Epub 2023 Apr 26. Glia. 2023. PMID: 37186402
Inactivation of Celsr2 enhances calcium influx in reactive astrocytes in time-lapse imaging. ...Similar phenotypes are found in mice with conditional knockout of Celsr2 in astrocytes. In Celsr2(-/-) mice, astrocyte phenotype is changed and neuroinflammation i …
Inactivation of Celsr2 enhances calcium influx in reactive astrocytes in time-lapse imaging. ...Similar phenotypes are found in mice …
Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human.
Wen Q, Weng H, Liu T, Yu L, Zhao T, Qin J, Li S, Wu Q, Tissir F, Qu Y, Zhou L. Wen Q, et al. Brain. 2022 Apr 18;145(2):670-683. doi: 10.1093/brain/awab317. Brain. 2022. PMID: 34983065 Free PMC article.
Celsr2 knockout promotes axon regeneration and fasciculation in mouse cultured spinal explants. ...In conclusion, Celsr2 negatively regulates motor axon regeneration and is a potential target to improve neural repair....
Celsr2 knockout promotes axon regeneration and fasciculation in mouse cultured spinal explants. ...In conclusion, Celsr2 negat …
CELSR2 deficiency suppresses lipid accumulation in hepatocyte by impairing the UPR and elevating ROS level.
Tan J, Che Y, Liu Y, Hu J, Wang W, Hu L, Zhou Q, Wang H, Li J. Tan J, et al. FASEB J. 2021 Oct;35(10):e21908. doi: 10.1096/fj.202100786RR. FASEB J. 2021. PMID: 34478580
CELSR2 mainly function in neural development and cilium polarity. ...Our results uncovered a new role of CELSR2 in regulating lipid homeostasis and UPR, suggesting CELSR2 may be a new therapeutic target for non-alcoholic fatty liver disease....
CELSR2 mainly function in neural development and cilium polarity. ...Our results uncovered a new role of CELSR2 in regulating …
Celsr2 regulates NMDA receptors and dendritic homeostasis in dorsal CA1 to enable social memory.
Chen B, Wang L, Li X, Shi Z, Duan J, Wei JA, Li C, Pang C, Wang D, Zhang K, Chen H, Na W, Zhang L, So KF, Zhou L, Jiang B, Yuan TF, Qu Y. Chen B, et al. Mol Psychiatry. 2022 Jul 4. doi: 10.1038/s41380-022-01664-x. Online ahead of print. Mol Psychiatry. 2022. PMID: 35789199
Celsr2-deficient mice exhibited defective social memory, with rather intact levels of sociability. In vivo fiber photometry recordings disclosed decreased neural activity of dorsal CA1 pyramidal neuron in Celsr2 mutants performing social memory task. Celsr2 d …
Celsr2-deficient mice exhibited defective social memory, with rather intact levels of sociability. In vivo fiber photometry recording …
Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.
Basta LP, Sil P, Jones RA, Little KA, Hayward-Lara G, Devenport D. Basta LP, et al. Front Cell Dev Biol. 2023 Jan 12;10:1064907. doi: 10.3389/fcell.2022.1064907. eCollection 2022. Front Cell Dev Biol. 2023. PMID: 36712970 Free PMC article.
Although the role of Celsr1 in epidermal planar polarity is well established, the contribution of the other major epidermally expressed Celsr protein, Celsr2, has not been investigated. Here, using two new CRISPR/Cas9-targeted Celsr1 and Celsr2 knockout mouse lines, …
Although the role of Celsr1 in epidermal planar polarity is well established, the contribution of the other major epidermally expressed Cels …
Association between Genetic Variants of CELSR2-PSRC1-SORT1 and Cardiovascular Diseases: A Systematic Review and Meta-Analysis.
Castillo-Avila RG, González-Castro TB, Tovilla-Zárate CA, Martínez-Magaña JJ, López-Narváez ML, Juárez-Rojop IE, Arias-Vázquez PI, Borgonio-Cuadra VM, Pérez-Hernández N, Rodríguez-Pérez JM. Castillo-Avila RG, et al. J Cardiovasc Dev Dis. 2023 Feb 21;10(3):91. doi: 10.3390/jcdd10030091. J Cardiovasc Dev Dis. 2023. PMID: 36975855 Free PMC article. Review.
A cluster of three genes CELSR2, PSRC1, and SORT1 has been associated with cardiovascular diseases. ...PheWas analysis showed associations with coronary artery disease and total cholesterol. Our results suggest a possible involvement of the CELSR2-PSRC1-SORT1 cluste …
A cluster of three genes CELSR2, PSRC1, and SORT1 has been associated with cardiovascular diseases. ...PheWas analysis showed associa …
Planar cell polarity protein Celsr2 maintains structural and functional integrity of adult cortical synapses.
Li C, Wei JA, Wang D, Luo Z, Pang C, Chen K, Duan J, Chen B, Zhou L, Tissir F, Shi L, So KF, Zhang L, Qu Y. Li C, et al. Prog Neurobiol. 2022 Dec;219:102352. doi: 10.1016/j.pneurobio.2022.102352. Epub 2022 Sep 8. Prog Neurobiol. 2022. PMID: 36089108
Celsr2 is highly expressed during development and remains expressed in adult neocortex. ...These phenotypes were accompanied with anomalies of both postsynaptic organization and presynaptic vesicles. Knockout of Celsr2 in adult mice recapitulated those features, fur …
Celsr2 is highly expressed during development and remains expressed in adult neocortex. ...These phenotypes were accompanied with ano …
Celsr2 Knockout Alleviates Inhibitory Synaptic Stripping and Benefits Motoneuron Survival and Axon Regeneration After Branchial Plexus Avulsion.
Yu L, Liu M, Li F, Wang Q, Wang M, So KF, Qu Y, Zhou L. Yu L, et al. Mol Neurobiol. 2023 Apr;60(4):1884-1900. doi: 10.1007/s12035-022-03198-3. Epub 2023 Jan 3. Mol Neurobiol. 2023. PMID: 36593433 Free PMC article.
Celsr2 was indicated to express in spinal motoneurons, excitatory and inhibitory interneurons, astrocytes, and a subset of oligodendrocytes using Celsr2(LacZ) mice. ...In conclusion, Celsr2 knockout enhances MHC I signaling, alleviates inhibitory synaptic str …
Celsr2 was indicated to express in spinal motoneurons, excitatory and inhibitory interneurons, astrocytes, and a subset of oligodendr …
Identification of CELSR2 as a novel prognostic biomarker for hepatocellular carcinoma.
Xu M, Zhu S, Xu R, Lin N. Xu M, et al. BMC Cancer. 2020 Apr 15;20(1):313. doi: 10.1186/s12885-020-06813-5. BMC Cancer. 2020. PMID: 32293343 Free PMC article.
The increased mRNA expression of CELSR2 was significantly associated with overall survival (OS) in HCC patients. ...CONCLUSIONS: This study demonstrated that data mining could efficiently reveal the roles of CELSR2 in HCC and its potential regulatory networks. The …
The increased mRNA expression of CELSR2 was significantly associated with overall survival (OS) in HCC patients. ...CONCLUSIONS: This …
151 results