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Did you mean cenp (2,274 results)?
CENPE contributes to pulmonary vascular remodeling in pulmonary hypertension.
Fang X, Xie M, Liu X, He Y. Fang X, et al. Biochem Biophys Res Commun. 2021 Jun 11;557:40-47. doi: 10.1016/j.bbrc.2021.04.010. Epub 2021 Apr 13. Biochem Biophys Res Commun. 2021. PMID: 33862458 Free article.
In addition, CENPE deficiency significantly inhibited the development of pulmonary vascular remodeling and right ventricular hypertrophy. ...Interestingly, we found that CENPE might exert its biological effect by targeting the transcription of CDK1 proteins....
In addition, CENPE deficiency significantly inhibited the development of pulmonary vascular remodeling and right ventricular hypertro …
CENPE Inhibition Leads to Mitotic Catastrophe and DNA Damage in Medulloblastoma Cells.
Iegiani G, Gai M, Di Cunto F, Pallavicini G. Iegiani G, et al. Cancers (Basel). 2021 Mar 1;13(5):1028. doi: 10.3390/cancers13051028. Cancers (Basel). 2021. PMID: 33804489 Free PMC article.
Since there is evidence that MB shares many molecular features with neural progenitors, we hypothesized that CENPE could be an effective target for MB treatment. In ONS-76 and DAOY cells, CENPE knockdown induced mitotic defects and apoptosis. ...GSK923295, induced e …
Since there is evidence that MB shares many molecular features with neural progenitors, we hypothesized that CENPE could be an effect …
CENPE promotes glioblastomas proliferation by directly binding to WEE1.
Ma C, Wang J, Zhou J, Liao K, Yang M, Li F, Zhang M. Ma C, et al. Transl Cancer Res. 2020 Feb;9(2):717-725. doi: 10.21037/tcr.2019.11.40. Transl Cancer Res. 2020. PMID: 35117417 Free PMC article.
Inhibition of CENPE expression resulted in proliferation inhibition of U251 and U87 cell. ...CONCLUSIONS: CENPE promotes GBM proliferation through WEE1 pathway and binding to WEE1....
Inhibition of CENPE expression resulted in proliferation inhibition of U251 and U87 cell. ...CONCLUSIONS: CENPE promotes GBM p …
Lin28A/CENPE Promoting the Proliferation and Chemoresistance of Acute Myeloid Leukemia.
Shi M, Niu J, Niu X, Guo H, Bai Y, Shi J, Li W, Sun K, Chen Y, Shao F. Shi M, et al. Front Oncol. 2021 Nov 12;11:763232. doi: 10.3389/fonc.2021.763232. eCollection 2021. Front Oncol. 2021. PMID: 34868981 Free PMC article.
RIP assay, RNA pull-down, and dual luciferase reporter analyses indicated that LIN28A bound specifically to the promoter region GGAGA of CENPE. In addition, the impacts of LIN28A on cell growth, apoptosis, cell cycle progression, and Ara-C chemoresistance were reverted by …
RIP assay, RNA pull-down, and dual luciferase reporter analyses indicated that LIN28A bound specifically to the promoter region GGAGA of …
Primary microcephaly gene CENPE is a novel biomarker and potential therapeutic target for non-WNT/non-SHH medulloblastoma.
Fang H, Zhang Y, Lin C, Sun Z, Wen W, Sheng H, Lin J. Fang H, et al. Front Immunol. 2023 Aug 1;14:1227143. doi: 10.3389/fimmu.2023.1227143. eCollection 2023. Front Immunol. 2023. PMID: 37593739 Free PMC article.
As a member of the centromere protein (CENP) family, centromeric protein E (CENPE) is a microtubule plus-end-directed kinetochore protein. Heterozygous mutations in CENPE can leads to primary microcephaly syndrome. It has been reported that CENPE is upregulat …
As a member of the centromere protein (CENP) family, centromeric protein E (CENPE) is a microtubule plus-end-directed kinetochore pro …
CENPE promotes lung adenocarcinoma proliferation and is directly regulated by FOXM1.
Shan L, Zhao M, Lu Y, Ning H, Yang S, Song Y, Chai W, Shi X. Shan L, et al. Int J Oncol. 2019 Jul;55(1):257-266. doi: 10.3892/ijo.2019.4805. Epub 2019 May 20. Int J Oncol. 2019. PMID: 31115500
Following knockdown of CENPE expression, the proliferation of lung cancer cells was inhibited. ...Overexpression of FOXM1 promoted the expression of CENPE and the proliferation of lung cancer cells. A chromatin immunoprecipitation assay identified that FOXM1 binds d …
Following knockdown of CENPE expression, the proliferation of lung cancer cells was inhibited. ...Overexpression of FOXM1 promoted th …
CENPE expression is associated with its DNA methylation status in esophageal adenocarcinoma and independently predicts unfavorable overall survival.
Zhu X, Luo X, Feng G, Huang H, He Y, Ma W, Zhang C, Zeng M, Liu H. Zhu X, et al. PLoS One. 2019 Feb 4;14(2):e0207341. doi: 10.1371/journal.pone.0207341. eCollection 2019. PLoS One. 2019. PMID: 30716092 Free PMC article.
Centrosome-associated protein E (CENPE) is a plus end-directed kinetochore motor protein, which plays a critical role in mitosis. ...The methylation status of cg27443373 and cg24651824 might play a critical role in modulating CENPE expression....
Centrosome-associated protein E (CENPE) is a plus end-directed kinetochore motor protein, which plays a critical role in mitosis. ... …
CENPE and LDHA were potential prognostic biomarkers of chromophobe renal cell carcinoma.
Wu HF, Liu H, Zhang ZW, Chen JM. Wu HF, et al. Eur J Med Res. 2023 Nov 4;28(1):481. doi: 10.1186/s40001-023-01449-0. Eur J Med Res. 2023. PMID: 37925501 Free PMC article.
CENPE was highly expressed while LDHA was lowly expressed in KICH samples, and the high expressions of 2 genes contributed to bad prognosis. The functions of CENPE and LDHA were mainly enriched in proliferation related pathways such as cell cycle and DNA replication …
CENPE was highly expressed while LDHA was lowly expressed in KICH samples, and the high expressions of 2 genes contributed to bad pro …
Expression of CENPE and its Prognostic Role in Non-small Cell Lung Cancer.
Hao X, Qu T. Hao X, et al. Open Med (Wars). 2019 Jun 17;14:497-502. doi: 10.1515/med-2019-0053. eCollection 2019. Open Med (Wars). 2019. PMID: 31259255 Free PMC article.
CENPE was highly expressed in NSCLC cell carcinoma compared with the control group (P < 0.05). Moreover, the expression of CENPE was correlated with the overall survival rate of CENPE. The overall survival rate of patients with high expression of CENPE …
CENPE was highly expressed in NSCLC cell carcinoma compared with the control group (P < 0.05). Moreover, the expression of CENP …
453 results