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Solvent System-Guided Extraction of Centaurium spicatum (L.) Fritch Provides Optimized Conditions for the Biological and Chemical Characteristics of the Herbal Extracts.
Božunović J, Ivanov M, Petrović J, Gašić U, Nakarada Đ, Milutinović M, Aničić N, Giba Z, Mišić D, Stojković D. Božunović J, et al. Pharmaceuticals (Basel). 2023 Feb 6;16(2):245. doi: 10.3390/ph16020245. Pharmaceuticals (Basel). 2023. PMID: 37259391 Free PMC article.
Spiked centaury (Centaurium spicatum) is a well-known medicinal plant from the Mediterranean region with various bioactivities, but there are no studies addressing the use of different solvent systems to improve its pharmacological potential. ...Moreover, the influe …
Spiked centaury (Centaurium spicatum) is a well-known medicinal plant from the Mediterranean region with various bioactivities …
Phytochemical and in silico studies for potential constituents from Centaurium spicatum as candidates against the SARS-CoV-2 main protease and RNA-dependent RNA polymerase.
Allam AE, Abouelela ME, Assaf HK, Sayed AM, Nafady AM, El-Shanawany MA, Takano F, Ohta T. Allam AE, et al. Nat Prod Res. 2022 Nov;36(22):5724-5731. doi: 10.1080/14786419.2021.2019732. Epub 2021 Dec 27. Nat Prod Res. 2022. PMID: 34961393
In the present study, a new secoiridoid glycoside lisianthoside II 1, along with seven known compounds 2-8, were isolated from Centaurium spicatum L. In-silico molecular docking and molecular dynamic simulation against SARS-CoV-2 Main protease (M(pro)) and RNA-depen …
In the present study, a new secoiridoid glycoside lisianthoside II 1, along with seven known compounds 2-8, were isolated from Centaurium …
Two new acetylated flavonoid glycosides from Centaurium spicatum L.
Allam AE, El-Shanawany MA, Backheet EY, Nafady AM, Takano F, Ohta T. Allam AE, et al. J Nat Med. 2012 Apr;66(2):388-93. doi: 10.1007/s11418-011-0594-y. Epub 2011 Oct 12. J Nat Med. 2012. PMID: 21989998
Two new acetylated flavonol glycosides, quercetin 3-O-[(2,4-diacetyl-alpha-L-rhamnopyranosyl)-(16)]-2,4-diacetyl-beta-D-galactopyranoside (1) and quercetin 3-O-[(2,4-diacetyl-alpha-L-rhamnopyranosyl)-(16)]-3,4-diacetyl-beta-D-galactopyranoside (2), in addition to two known acetyl …
Two new acetylated flavonol glycosides, quercetin 3-O-[(2,4-diacetyl-alpha-L-rhamnopyranosyl)-(16)]-2,4-diacetyl-beta-D-galactopyranoside (1 …
Unveiling the tyrosinase inhibitory potential of phenolics from Centaurium spicatum: Bridging in silico and in vitro perspectives.
Alruhaimi RS, Mahmoud AM, Elbagory I, Ahmeda AF, El-Bassuony AA, Lamsabhi AM, Kamel EM. Alruhaimi RS, et al. Bioorg Chem. 2024 Jun;147:107397. doi: 10.1016/j.bioorg.2024.107397. Epub 2024 Apr 25. Bioorg Chem. 2024. PMID: 38691905
Phenolics, abundant in plants, constitute a significant portion of phytoconstituents consumed in the human diet. The phytochemical screening of the aerial parts of Centaurium spicatum led to the isolation of five phenolics. The anti-tyrosinase activities of the isol …
Phenolics, abundant in plants, constitute a significant portion of phytoconstituents consumed in the human diet. The phytochemical screening …
Secoiridoids and Xanthones in the genus Centaurium.
van der Sluis WG, Labadie RP. van der Sluis WG, et al. Planta Med. 1981 Mar;41(3):221-31. doi: 10.1055/s-2007-971707. Planta Med. 1981. PMID: 17401846
Overground parts of Centaurium spicatum (L.) Fritsch (Gentianaceae) from two different habitats have been investigated on their content of Secoiridoid glucosides. ...The composition of sweroside (I), swertiamarin (II) and gentiopicrin (III) in C. spicatum is …
Overground parts of Centaurium spicatum (L.) Fritsch (Gentianaceae) from two different habitats have been investigated on thei …
Anticomplement and antioxidant activities of new acetylated flavonoid glycosides from Centaurium spicatum.
Shahat AA, Cos P, Hermans N, Apers S, De Bruyne T, Pieters L, Berghe DV, Vlietinck AJ. Shahat AA, et al. Planta Med. 2003 Dec;69(12):1153-6. doi: 10.1055/s-2003-818009. Planta Med. 2003. PMID: 14750035
In addition to the three acetylated flavonol glycosides, quercetin 3- O-[(2,3,4-triacetyl-alpha-rhamnopyranosyl)-(1-->6)]-beta-galactopyranoside, quercetin 3- O-[(2,3,4-triacetyl-alpha-rhamnopyranosyl)-(1-->6)]-3-acetyl-beta-galactopyranoside, and quercetin 3- O-[(2,3,4- tr …
In addition to the three acetylated flavonol glycosides, quercetin 3- O-[(2,3,4-triacetyl-alpha-rhamnopyranosyl)-(1-->6)]-beta-galactopyr …