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Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development.
iScience. 2020 Mar 27;23(3):100941. doi: 10.1016/j.isci.2020.100941. Epub 2020 Feb 27.
iScience. 2020.
PMID: 32169821
Free PMC article.
Inhibition of MEK and ATR is effective in a B-cell acute lymphoblastic leukemia model driven by Mll-Af4 and activated Ras.
Chu SH, Song EJ, Chabon JR, Minehart J, Matovina CN, Makofske JL, Frank ES, Ross K, Koche RP, Feng Z, Xu H, Krivtsov A, Nussenzweig A, Armstrong SA.
Chu SH, et al. Among authors: chabon jr.
Blood Adv. 2018 Oct 9;2(19):2478-2490. doi: 10.1182/bloodadvances.2018021592.
Blood Adv. 2018.
PMID: 30266823
Free PMC article.
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SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.
Mar BG, Chu SH, Kahn JD, Krivtsov AV, Koche R, Castellano CA, Kotlier JL, Zon RL, McConkey ME, Chabon J, Chappell R, Grauman PV, Hsieh JJ, Armstrong SA, Ebert BL.
Mar BG, et al.
Blood. 2017 Dec 14;130(24):2631-2641. doi: 10.1182/blood-2017-03-775569. Epub 2017 Oct 10.
Blood. 2017.
PMID: 29018079
Free PMC article.
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Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG.
Carmi Y, et al.
JCI Insight. 2016 Nov 3;1(18):e89020. doi: 10.1172/jci.insight.89020.
JCI Insight. 2016.
PMID: 27812544
Free PMC article.
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Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG.
Spitzer MH, et al.
Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19.
Cell. 2017.
PMID: 28111070
Free PMC article.
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