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KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress.
Issa N, Bjeije H, Wilson ER, Krishnan A, Dunuwille WMB, Parsons TM, Zhang CR, Han W, Young AL, Ren Z, Ge K, Wang ES, Weng AP, Cashen A, Spencer DH, Challen GA. Issa N, et al. Among authors: challen ga. Leukemia. 2023 Apr;37(4):728-740. doi: 10.1038/s41375-023-01853-9. Epub 2023 Feb 17. Leukemia. 2023. PMID: 36797416 Free PMC article.
Dnmt3a regulates T-cell development and suppresses T-ALL transformation.
Kramer AC, Kothari A, Wilson WC, Celik H, Nikitas J, Mallaney C, Ostrander EL, Eultgen E, Martens A, Valentine MC, Young AL, Druley TE, Figueroa ME, Zhang B, Challen GA. Kramer AC, et al. Among authors: challen ga. Leukemia. 2017 Nov;31(11):2479-2490. doi: 10.1038/leu.2017.89. Epub 2017 Mar 21. Leukemia. 2017. PMID: 28321121 Free PMC article.
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.
Maifrede S, Le BV, Nieborowska-Skorska M, Golovine K, Sullivan-Reed K, Dunuwille WMB, Nacson J, Hulse M, Keith K, Madzo J, Caruso LB, Gazze Z, Lian Z, Padella A, Chitrala KN, Bartholdy BA, Matlawska-Wasowska K, Di Marcantonio D, Simonetti G, Greiner G, Sykes SM, Valent P, Paietta EM, Tallman MS, Fernandez HF, Litzow MR, Minden MD, Huang J, Martinelli G, Vassiliou GS, Tempera I, Piwocka K, Johnson N, Challen GA, Skorski T. Maifrede S, et al. Among authors: challen ga. Cancer Res. 2021 Oct 1;81(19):5089-5101. doi: 10.1158/0008-5472.CAN-20-3761. Epub 2021 Jul 2. Cancer Res. 2021. PMID: 34215619 Free PMC article.
Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21.
Zhang CR, Ostrander EL, Kukhar O, Mallaney C, Sun J, Haussler E, Celik H, Koh WK, King KY, Gontarz P, Challen GA. Zhang CR, et al. Among authors: challen ga. Blood Cancer Discov. 2022 May 5;3(3):220-239. doi: 10.1158/2643-3230.BCD-21-0132. Blood Cancer Discov. 2022. PMID: 35394496 Free PMC article.
Effect of Clonal Hematopoiesis on Cardiovascular Disease in People Living with HIV.
Wiley B, Parsons TM, Burkart S, Young AL, Erlandson KM, Tassiopoulos KK, Wu K, Gurnett C, Presti RM, Bolton KL, Challen GA. Wiley B, et al. Among authors: challen ga. Exp Hematol. 2022 Oct;114:18-21. doi: 10.1016/j.exphem.2022.07.304. Epub 2022 Aug 6. Exp Hematol. 2022. PMID: 35940373 Free PMC article.
59 results