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Crystallographic Fragment Screen of Coxsackievirus A16 2A Protease identifies new opportunities for the development of broad-spectrum anti-enterovirals.
Lithgo RM, Tomlinson CWE, Fairhead M, Winokan M, Thompson W, Wild C, Aschenbrenner JC, Balcomb BH, Marples PG, Chandran AV, Golding M, Koekemoer L, Williams EP, Wang S, Ni X, MacLean E, Giroud C, Godoy AS, Xavier MA, Walsh M, Fearon D, von Delft F. Lithgo RM, et al. Among authors: chandran av. bioRxiv [Preprint]. 2024 Apr 29:2024.04.29.591684. doi: 10.1101/2024.04.29.591684. bioRxiv. 2024. PMID: 38746446 Free PMC article. Preprint.
Crystallographic fragment screening delivers diverse chemical scaffolds for Zika virus NS2B-NS3 protease inhibitor development.
Ni X, Godoy AS, Marples PG, Fairhead M, Balcomb BH, Ferla MP, Tomlinson CWE, Wang S, Giroud C, Aschenbrenner JC, Lithgo RM, Winokan M, Chandran AV, Thompson W, Xavier MA, Williams EP, Walsh M, Fearon D, Koekemoer L, von Delft F. Ni X, et al. Among authors: chandran av. bioRxiv [Preprint]. 2024 Apr 29:2024.04.29.591502. doi: 10.1101/2024.04.29.591502. bioRxiv. 2024. PMID: 38746305 Free PMC article. Preprint.
High-throughput crystallographic fragment screening of Zika virus NS3 Helicase.
Godoy AS, Mesquita NCMR, Noske GD, Gawriljuk VO, Lithgo RM, Balcomb BH, Aschenbrenner JC, Tomlinson CWE, Winokan M, Scheen J, Marples PG, Chandran AV, Ni X, Thompson W, Fairhead M, Fearon D, Koekemoer L, Xavier ME, Walsh M, Oliva G, von Delft F. Godoy AS, et al. Among authors: chandran av. bioRxiv [Preprint]. 2024 Apr 29:2024.04.27.591279. doi: 10.1101/2024.04.27.591279. bioRxiv. 2024. PMID: 38746241 Free PMC article. Preprint.
Blood RNA biomarkers for tuberculosis screening in people living with HIV before antiretroviral therapy initiation: a diagnostic accuracy study.
Mann T, Gupta RK, Reeve BWP, Ndlangalavu G, Chandran A, Krishna AP, Calderwood CJ, Tshivhula H, Palmer Z, Naidoo S, Mbu DL, Theron G, Noursadeghi M. Mann T, et al. Among authors: chandran a. Lancet Glob Health. 2024 May;12(5):e783-e792. doi: 10.1016/S2214-109X(24)00029-9. Epub 2024 Apr 4. Lancet Glob Health. 2024. PMID: 38583459 Free article.
Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood.
Mlodnicka A, Mansolf M, Chandran A, Aris IM, Calub CA, Ahmad S, Shapiro A, Cochran D, Restrepo B, Schmidt R, Hertz-Picciotto I, Bennett D, Gold DR, O'Shea TM, Leve L, Schweitzer JB; program collaborators for Environmental influences on Child Health Outcomes*. Mlodnicka A, et al. Among authors: chandran a. Dev Psychopathol. 2024 Mar 27:1-10. doi: 10.1017/S0954579424000695. Online ahead of print. Dev Psychopathol. 2024. PMID: 38532736
628 results