Charpentier TH - Search Results

1

The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography.

Charpentier TH, Thompson LE, Liriano MA, Varney KM, Wilder PT, Pozharski E, Toth EA, Weber DJ. Charpentier TH, et al. J Mol Biol. 2010 Mar 12;396(5):1227-43. doi: 10.1016/j.jmb.2009.12.057. Epub 2010 Jan 4. J Mol Biol. 2010. PMID: 20053360 Free PMC article.

2

Design of Inhibitors for S100B.

Markowitz J, Mackerell AD Jr, Carrier F, Charpentier TH, Weber DJ. Markowitz J, et al. Among authors: charpentier th. Curr Top Med Chem. 2005;5(12):1093-108. doi: 10.2174/156802605774370865. Curr Top Med Chem. 2005. PMID: 16248785 Review.

3

Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B.

Wilder PT, Lin J, Bair CL, Charpentier TH, Yang D, Liriano M, Varney KM, Lee A, Oppenheim AB, Adhya S, Carrier F, Weber DJ. Wilder PT, et al. Among authors: charpentier th. Biochim Biophys Acta. 2006 Nov;1763(11):1284-97. doi: 10.1016/j.bbamcr.2006.08.024. Epub 2006 Aug 25. Biochim Biophys Acta. 2006. PMID: 17010455 Free article.

4

Divalent metal ion complexes of S100B in the absence and presence of pentamidine.

Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, MacKerell AD Jr, Coop A, Toth EA, Weber DJ. Charpentier TH, et al. J Mol Biol. 2008 Sep 26;382(1):56-73. doi: 10.1016/j.jmb.2008.06.047. Epub 2008 Jun 24. J Mol Biol. 2008. PMID: 18602402 Free PMC article.

5

Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.

Charpentier TH, Wilder PT, Liriano MA, Varney KM, Zhong S, Coop A, Pozharski E, MacKerell AD Jr, Toth EA, Weber DJ. Charpentier TH, et al. Biochemistry. 2009 Jul 7;48(26):6202-12. doi: 10.1021/bi9005754. Biochemistry. 2009. PMID: 19469484 Free PMC article.

6

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.

Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ. Wilder PT, et al. Among authors: charpentier th. Int J High Throughput Screen. 2010 Jul 7;2010(1):109-126. doi: 10.2147/IJHTS.S8210. Int J High Throughput Screen. 2010. PMID: 21132089 Free PMC article.

7

Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.

Cavalier MC, Ansari MI, Pierce AD, Wilder PT, McKnight LE, Raman EP, Neau DB, Bezawada P, Alasady MJ, Charpentier TH, Varney KM, Toth EA, MacKerell AD Jr, Coop A, Weber DJ. Cavalier MC, et al. Among authors: charpentier th. J Med Chem. 2016 Jan 28;59(2):592-608. doi: 10.1021/acs.jmedchem.5b01369. Epub 2016 Jan 13. J Med Chem. 2016. PMID: 26727270 Free PMC article.

8

Hydrocarbon-stapled helices: a novel approach for blocking protein-protein interactions.

Wilder PT, Charpentier TH, Weber DJ. Wilder PT, et al. Among authors: charpentier th. ChemMedChem. 2007 Aug;2(8):1149-51. doi: 10.1002/cmdc.200700102. ChemMedChem. 2007. PMID: 17554748 No abstract available.

9

Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA.

Malashkevich VN, Varney KM, Garrett SC, Wilder PT, Knight D, Charpentier TH, Ramagopal UA, Almo SC, Weber DJ, Bresnick AR. Malashkevich VN, et al. Among authors: charpentier th. Biochemistry. 2008 May 6;47(18):5111-26. doi: 10.1021/bi702537s. Epub 2008 Apr 15. Biochemistry. 2008. PMID: 18410126 Free PMC article.

10

Getting a grip on calcium regulation.

Blaustein MP, Charpentier TH, Weber DJ. Blaustein MP, et al. Among authors: charpentier th. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18349-50. doi: 10.1073/pnas.0709008104. Epub 2007 Nov 14. Proc Natl Acad Sci U S A. 2007. PMID: 18003903 Free PMC article. No abstract available.

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