Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases.
Sparks JD, O'Dell C, Chamberlain JM, Sparks CE.
Sparks JD, et al.
Biochem Biophys Res Commun. 2013 Jun 14;435(4):616-20. doi: 10.1016/j.bbrc.2013.05.029. Epub 2013 May 15.
Biochem Biophys Res Commun. 2013.
PMID: 23685141
Free PMC article.
Thapsigargan, an inducer of endoplasmic reticulum (ER) stress, and a recently demonstrated autophagy inhibitor, blocked apo B secretion which contrasted with other autophagy inhibitors and mutant Vps34 results which were permissive with respect to apo B secretion. Pulse chase …
Thapsigargan, an inducer of endoplasmic reticulum (ER) stress, and a recently demonstrated autophagy inhibitor, blocked apo B secretion whic …