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Tailoring acyclovir prodrugs with enhanced antiviral activity: rational design, synthesis, human plasma stability and in vitro evaluation.
Amino Acids. 2018 Aug;50(8):1131-1143. doi: 10.1007/s00726-018-2590-y. Epub 2018 May 19.
Amino Acids. 2018.
PMID: 29779181
Modifications on the heterocyclic base of ganciclovir, penciclovir, acyclovir - syntheses and antiviral properties.
Chuchkov K, Chayrov R, Hinkov A, Todorov D, Shishkova K, Stankova IG.
Chuchkov K, et al.
Nucleosides Nucleotides Nucleic Acids. 2020;39(7):979-990. doi: 10.1080/15257770.2020.1725043. Epub 2020 Apr 20.
Nucleosides Nucleotides Nucleic Acids. 2020.
PMID: 32312162
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Synthetic Analogues of Aminoadamantane as Influenza Viral Inhibitors-In Vitro, In Silico and QSAR Studies.
Chayrov R, Parisis NA, Chatziathanasiadou MV, Vrontaki E, Moschovou K, Melagraki G, Sbirkova-Dimitrova H, Shivachev B, Schmidtke M, Mitrev Y, Sticha M, Mavromoustakos T, Tzakos AG, Stankova I.
Chayrov R, et al.
Molecules. 2020 Sep 1;25(17):3989. doi: 10.3390/molecules25173989.
Molecules. 2020.
PMID: 32883012
Free PMC article.
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Synthetic analogues of memantine as neuroprotective and influenza viral inhibitors: in vitro and physicochemical studies.
Tencheva A, Liu R, Volkova TV, Chayrov R, Mitrev Y, Štícha M, Li Y, Jiang H, Li Z, Stankova I, Perlovich GL.
Tencheva A, et al.
Amino Acids. 2020 Dec;52(11-12):1559-1580. doi: 10.1007/s00726-020-02914-4. Epub 2020 Nov 15.
Amino Acids. 2020.
PMID: 33191465
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Synthesis, Neuroprotective Effect and Physicochemical Studies of Novel Peptide and Nootropic Analogues of Alzheimer Disease Drug.
Chayrov R, Volkova T, Perlovich G, Zeng L, Li Z, Štícha M, Liu R, Stankova I.
Chayrov R, et al.
Pharmaceuticals (Basel). 2022 Sep 5;15(9):1108. doi: 10.3390/ph15091108.
Pharmaceuticals (Basel). 2022.
PMID: 36145329
Free PMC article.
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Tyrosinyl-amantadine: A New Amantadine Derivative With an Ameliorative Effect in a 6-OHDA Experimental Model of Parkinson's Disease in Rats.
Lazarova M, Tancheva L, Chayrov R, Tzvetanova E, Alexandrova A, Popatanasov A, Uzunova D, Stefanova M, Stankova I, Kalfin R.
Lazarova M, et al.
J Mol Neurosci. 2022 Apr;72(4):900-909. doi: 10.1007/s12031-021-01964-x. Epub 2022 Jan 28.
J Mol Neurosci. 2022.
PMID: 35091981
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