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p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor.
Qi X, Tang J, Pramanik R, Schultz RM, Shirasawa S, Sasazuki T, Han J, Chen G. Qi X, et al. Among authors: chen g. J Biol Chem. 2004 May 21;279(21):22138-44. doi: 10.1074/jbc.M313964200. Epub 2004 Mar 22. J Biol Chem. 2004. PMID: 15037631 Free article.
Our previous work demonstrated the inhibitory activity of the p38 pathway in Ras proliferative signaling in experimental NIH 3T3 cells (Chen, G., Hitomi, M., Han, J., and Stacey, D. W. (2000) J. Biol. ...
Our previous work demonstrated the inhibitory activity of the p38 pathway in Ras proliferative signaling in experimental NIH 3T3 cells (C
Essential role of p38gamma in K-Ras transformation independent of phosphorylation.
Tang J, Qi X, Mercola D, Han J, Chen G. Tang J, et al. Among authors: chen g. J Biol Chem. 2005 Jun 24;280(25):23910-7. doi: 10.1074/jbc.M500699200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851477 Free PMC article.
Whereas the ERK MAPK pathway is required for Ras transformation, our previous works established that the p38 activity is inhibitory to Ras signaling in both experimental and ras-mutated cancer cells (Chen, G., Hitomi, M., Han, J., and Stacey, D. W. (2000) J. Biol. C …
Whereas the ERK MAPK pathway is required for Ras transformation, our previous works established that the p38 activity is inhibitory to Ras s …
Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity.
Li QP, Qi X, Pramanik R, Pohl NM, Loesch M, Chen G. Li QP, et al. Among authors: chen g. J Biol Chem. 2007 Jan 19;282(3):1544-51. doi: 10.1074/jbc.M604052200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121851 Free article.
., Schultz, R. M., Maitra, R. K., Han, J., DeLuca, H. F., and Chen, G. (2002) J. Biol. Chem. 277, 25884-25892) and VDR inhibits cell death in response to p38 MAPK activation (Qi, X., Tang, J., Pramanik, R., Schultz, R. M., Shirasawa, S., Sasazuki, T., Han, J., and …
., Schultz, R. M., Maitra, R. K., Han, J., DeLuca, H. F., and Chen, G. (2002) J. Biol. Chem. 277, 25884-25892) and VDR inhibit …
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